Version2.1 2021-01-13T17:56:08Z 10.1021/jm300687e Gaussian16 RevisionB.01 CFLINN 29-Dec-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE C[C@@H](c1nnc(n1c2ccc(cc2)Cl)SCC(=O)Nc3ccc(c(c3)[N+](=O)[O-])Cl)[NH+](C)C C03379702 RHF 6-31G(d) (6D,7F) C[C@@H](c1nnc(n1c2ccc(cc2)Cl)SCC(=O)Nc3ccc(c(c3)[N+](=O)[O-])Cl)[NH+](C)C C01[X(C20H21Cl2N6O3S1)] 153 C1 534 O=C(Nc1ccc(c(c1)[N+](=O)[O-])Cl)CSc1nnc(n1c1ccc(cc1)Cl)[C@@H]([NH+](C)C)C O=C(Nc1ccc(c(c1)[N+](=O)[O-])Cl)CSc1nnc(n1c1ccc(cc1)Cl)[C@@H]([NH+](C)C)C C[C@H]([NH+](C)C)c1nnc(SCC(=O)Nc2ccc(Cl)c(c2)[N+]([O-])=O)n1c3ccc(Cl)cc3 InChIKey=KXDMYRVHYYAXIB-LBPRGKRZSA-O InChI=1S/C20H20Cl2N6O3S/c1-12(26(2)3)19-24-25-20(27(19)15-7-4-13(21)5-8-15)32-11-18(29)23-14-6-9-16(22)17(10-14)28(30)31/h4-10,12H,11H2,1-3H3,(H,23,29)/p+1/t12-/m0/s1 InChI=1/C20H20Cl2N6O3S/c1-12(26(2)3)19-24-25-20(27(19)15-7-4-13(21)5-8-15)32-11-18(29)23-14-6-9-16(22)17(10-14)28(30)31/h4-10,12H,11H2,1-3H3,(H,23,29)/p+1/t12-/m0/s1/fC20H21Cl2N6O3S/h23,26H/q+1 C[C@@H](c1nnc(n1c2ccc(cc2)Cl)SCC(=O)Nc3ccc(c(c3)[N+](=O)[O-])Cl)[NH+](C)C C01[X(C20H21Cl2N6O3S1)] 153 C01 534 O=C(Nc1ccc(c(c1)[N+](=O)[O-])Cl)CSc1nnc(n1c1ccc(cc1)Cl)[C@@H]([NH+](C)C)C O=C(N[C]1[CH][CH][C]([C]([CH]1)[N]([O])[O])Cl)CS[C]1[N][N][C]([N@@]1[C]1[CH][CH][C]([CH][CH]1)Cl)[C@@H]([NH](C)C)C C[C@@H]([C]1[N][N][C](SCC(=O)N[C]2[CH][CH][C](Cl)[C]([CH]2)N([O])[O])N1[C]3[CH][CH][C](Cl)[CH][CH]3)[NH](C)C InChIKey=YZRQJGPTIMCVEF-LBPRGKRZSA-N InChI=1S/C20H21Cl2N6O3S/c1-12(26(2)3)19-24-25-20(27(19)15-7-4-13(21)5-8-15)32-11-18(29)23-14-6-9-16(22)17(10-14)28(30)31/h4-10,12,26H,11H2,1-3H3,(H,23,29)/t12-/m0/s1 InChI=1/C20H21Cl2N6O3S/c1-12(26(2)3)19-24-25-20(27(19)15-7-4-13(21)5-8-15)32-11-18(29)23-14-6-9-16(22)17(10-14)28(30)31/h4-10,12,26H,11H2,1-3H3,(H,23,29)/t12-/m0/s1/f/h23H 3462.1905095652 -2636.9936913 1-A 31853.5060 128 406 534 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298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 6 6 1 6 7 7 6 7 6 6 6 6 6 6 17 16 6 6 8 7 6 6 6 6 6 6 7 8 8 17 7 1 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 12.00000 1.00783 12.00000 14.00307 14.00307 12.00000 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 34.96885 31.97207 12.00000 12.00000 15.99491 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 14.00307 15.99491 15.99491 34.96885 14.00307 1.00783 12.00000 12.00000 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
9743.6412 51680.2292 59965.2499 0.99987 -0.01634 -0.00009 0.01634 0.99986 -0.00431 0.00016 0.00431 0.99999 1 0.00889 0.00168 0.00144 0.18522 0.03492 0.03010 8.72 19.39 28.18 47.94 51.53 56.04 67.15 72.36 87.92 99.50 116.70 126.03 146.98 165.66 178.09 197.05 211.93 250.66 269.75 297.49 319.11 329.39 367.96 399.96 405.93 425.67 438.78 444.71 464.21 510.29 529.25 543.88 576.25 596.01 601.53 648.61 664.21 667.93 684.67 695.78 737.14 752.80 772.14 794.75 798.24 824.12 852.64 920.40 954.54 966.82 998.02 1037.84 1058.16 1117.87 1126.47 1132.22 1153.34 1177.60 1186.26 1196.90 1248.67 1258.02 1275.34 1337.57 1360.13 1378.23 1385.21 1431.73 1459.94 1466.84 1470.89 1555.72 1560.54 1565.99 1576.80 1584.43 1596.94 1608.43 1613.91 1641.67 1655.61 1672.56 1706.13 1717.61 1721.51 1748.10 1761.26 1786.66 1827.84 1830.12 1862.42 1866.77 1867.77 1873.32 1898.35 1905.88 1972.40 1981.32 1987.32 2054.30 2061.01 2081.56 2141.09 2147.07 2160.29 2235.94 2242.68 2252.08 2261.81 2278.87 2286.17 2307.17 2320.54 2334.44 2338.50 2350.61 2367.83 2368.81 2370.02 2377.86 2399.06 2403.71 2409.04 2435.72 2478.42 2536.77 2545.97 2571.37 2589.69 2605.82 2696.28 2840.20 4656.91 4700.44 4701.24 4710.29 4731.75 4777.01 4779.64 4785.47 4835.64 4843.77 4866.23 4875.42 4876.41 4879.00 4904.03 4906.19 4911.51 4913.94 4990.33 5194.07 5555.64 0.438029 0.467078 0.468022 0.370978 -2636.555663 -2636.526613 -2636.525669 -2636.622714 3.254905D-04
MUNgauss RevisionA2.0 retrievium 13-Jan-2021 DUDE C[C@@H](c1nnc(n1c2ccc(cc2)Cl)SCC(=O)Nc3ccc(c(c3)[N+](=O)[O-])Cl)[NH+](C)C C03379702 RHF 6-31G(d) (6D,10F) C1 495.077291 |X|Y|Z| 69.913548 24.290284 162.403777
65.092361 21 6 7 16 16 4 1
|36.858105| |12.453026|36.858105| |8.853589|17.615551|0.500000| |7.607960|12.643018|0.246209|36.858105| |5.708734|7.816206|0.163572|14.925119|53.358707| |4.346281|5.312218|0.124722|8.912791|19.044140|53.358707| |4.382494|5.264594|0.130729|8.902154|12.166057|20.157828|36.858105| |5.775435|7.421755|0.187014|14.014458|11.947905|11.868688|13.899280|53.358707| |5.207070|6.015612|0.175968|7.564825|7.279822|7.255903|7.555210|18.081447|36.858105| |4.268557|5.137352|0.167362|5.756516|5.941913|5.850967|5.556385|10.641066|13.751067|36.858105| |3.593378|3.986427|0.129269|4.149831|4.546233|4.502499|4.071559|6.999594|7.953758|13.770351|36.858105| |3.494823|3.591196|0.111466|3.702253|4.125426|4.118857|3.702795|6.195232|6.923943|7.969307|13.751421|36.858105| |3.939394|3.840373|0.113406|4.061085|4.494688|4.524460|4.144138|6.997937|7.955846|6.858104|7.900038|13.751108|36.858105| |4.891758|4.840609|0.136748|5.529162|5.829168|5.897434|5.740349|10.632138|13.748668|7.912075|6.854589|7.966434|13.769850|36.858105| |2.758735|2.771641|0.085025|2.782502|3.238417|3.234049|2.782219|4.383430|4.251044|4.784661|7.064920|11.011944|7.063409|4.783565|448.794386| |3.250574|3.628496|0.095695|4.969771|6.731903|9.481472|10.872600|9.483401|5.958860|4.852805|3.897043|3.665730|4.078971|5.210203|22.708065|388.023441| |2.762779|3.051925|0.078859|4.021639|6.109384|8.984950|7.095296|6.450823|3.928886|3.411562|2.867871|2.717546|2.959106|3.564900|17.891457|74.585160|36.858105| |2.302156|2.483755|0.065568|3.085504|4.503138|5.888286|4.694146|4.881867|3.228742|2.915149|2.570058|2.480060|2.666806|3.055708|16.884019|50.100452|12.514843|36.858105| |2.217916|2.372042|0.063637|2.894349|4.063926|5.108745|4.284158|4.688291|3.266892|2.991390|2.701503|2.639681|2.826500|3.160266|18.113088|48.441594|8.014171|15.939344|73.516695| |2.061581|2.208926|0.058113|2.676024|3.983404|5.029214|3.744593|4.042726|2.667505|2.444642|2.183466|2.110767|2.250854|2.538410|14.685689|34.219260|7.929069|14.047770|14.931599|53.358707| |1.795045|1.901696|0.050515|2.238044|3.273958|3.949205|2.951892|3.343049|2.270402|2.118890|1.938123|1.890077|1.996917|2.194863|13.461877|26.080244|5.041582|7.649173|11.572990|18.382195|36.858105| |1.693625|1.781031|0.047813|2.069618|2.956711|3.499540|2.690742|3.127589|2.186542|2.061731|1.922323|1.893664|1.991067|2.145611|13.679502|24.232000|4.207877|6.278651|11.679709|10.478025|13.700030|36.858105| |1.509713|1.577509|0.042514|1.800039|2.560599|2.958310|2.251654|2.681173|1.891997|1.802490|1.702493|1.683913|1.757983|1.867491|12.379599|19.448149|3.234129|4.319678|7.987452|6.975299|7.949529|13.789076|36.858105| |1.423362|1.486547|0.039934|1.684355|2.418662|2.767715|2.063032|2.466560|1.724454|1.645026|1.549438|1.526754|1.590994|1.694037|11.251229|17.199413|2.898093|3.661739|6.402535|6.154696|6.792872|7.869623|13.745139|36.858105| |1.484205|1.557120|0.041536|1.774878|2.588340|2.981747|2.179459|2.573834|1.768466|1.677122|1.560744|1.527759|1.597018|1.721444|11.148372|17.881526|3.144745|3.905148|6.418246|7.081642|7.935803|6.905217|8.039716|13.746943|36.858105| |1.658170|1.751850|0.046424|2.031685|3.000737|3.540023|2.569778|2.960029|2.000677|1.878162|1.723137|1.677773|1.764600|1.931099|12.058337|21.373130|4.018049|5.173971|7.911025|10.889542|13.768334|7.970593|6.941691|7.897488|13.792758|36.858105| |1.385698|1.451167|0.038662|1.635955|2.396873|2.716059|1.954220|2.334387|1.599048|1.521838|1.417861|1.385493|1.443884|1.553441|10.159706|15.504732|2.682127|3.130468|5.116515|5.424283|5.153040|4.517371|5.092699|7.609186|13.035968|7.920416|53.358707| |1.416415|1.478963|0.039148|1.666882|2.465139|2.787067|1.976389|2.355646|1.598498|1.510657|1.400301|1.369144|1.434265|1.552882|9.999360|15.399531|2.692869|3.048761|4.878194|5.291588|4.691690|3.935907|4.151215|5.485435|8.414899|7.057554|21.683785|73.516695| |1.287784|1.349570|0.036157|1.508360|2.194758|2.459741|1.777046|2.147883|1.483113|1.424630|1.336009|1.303915|1.349148|1.439985|9.636854|14.013982|2.359990|2.719537|4.543022|4.517447|4.151094|3.877292|4.529600|6.635351|8.378413|5.616301|21.849965|15.989060|73.516695| |1.263381|1.311099|0.035383|1.462468|2.083431|2.337409|1.741261|2.124564|1.501266|1.443481|1.375636|1.361713|1.411103|1.483850|10.184969|14.196870|2.298079|2.763175|4.921583|4.367002|4.206880|4.783255|7.116541|11.034951|6.914784|4.726550|8.199649|8.053010|11.436993|448.794386| |7.487132|12.544376|0.252119|7.937786|9.753319|6.489640|4.288722|7.008983|4.201465|3.867365|3.146841|2.831993|2.947698|3.517136|18.480661|21.957618|2.783507|2.284439|3.821844|2.838484|1.806838|1.676202|1.496603|1.427773|1.508192|1.692750|1.936257|2.592327|2.358166|10.148835|53.358707| |6.603446|9.381069|0.184482|8.118800|12.274647|7.507538|4.586141|7.008861|3.983264|3.558990|2.895843|2.641624|2.795517|3.379468|17.312001|22.948869|3.006228|2.425033|3.990608|3.034539|1.914129|1.755127|1.561366|1.495321|1.592425|1.800227|2.048037|2.759232|2.481343|10.573237|25.567083|0.500000| |6.612253|7.489166|0.178936|5.087972|6.462008|4.826264|3.263647|5.165484|3.341711|3.135763|2.702571|2.501183|2.595322|2.973892|16.915850|17.903499|2.310740|1.954533|3.296300|2.464872|1.596820|1.491682|1.347905|1.293448|1.361945|1.511096|1.763023|2.365285|2.157466|9.294830|17.377502|0.257778|36.858105| |4.960845|7.646510|0.208339|6.282970|8.078677|5.955249|3.990348|6.284363|3.891675|3.874493|3.148365|2.727994|2.727882|3.162770|18.014367|21.188120|2.710574|2.247014|3.766399|2.802521|1.791522|1.663213|1.488343|1.422159|1.502207|1.682420|1.932037|2.572893|2.366385|10.119139|17.327417|0.260892|7.780730|36.858105| |17.612360|8.944053|0.212681|7.044555|7.006895|5.782919|4.581071|8.540535|6.218998|4.781848|4.078836|4.134677|4.932284|6.366056|25.351680|24.846087|2.855303|2.397051|4.165560|2.880687|1.843853|1.755579|1.559838|1.458668|1.510498|1.686287|1.905542|2.532878|2.311231|10.382995|7.505194|0.140291|4.846323|4.137908|0.500000| |17.614009|8.733709|0.213912|5.512927|6.043556|4.790873|3.539346|6.081215|4.286427|3.765431|3.322770|3.253338|3.556951|4.121472|21.390103|19.673649|2.392451|2.039478|3.516886|2.513479|1.629701|1.546955|1.391935|1.317301|1.369140|1.516066|1.749615|2.333662|2.134943|9.465831|9.038785|0.155114|7.111047|4.638131|0.303662|0.500000| |17.581730|8.767990|0.173067|6.881988|8.046140|6.106892|4.299353|7.094048|4.454253|3.625635|3.084522|3.039495|3.468127|4.301838|19.712698|22.706974|2.814102|2.332200|3.943445|2.872530|1.832595|1.714961|1.528861|1.448590|1.519586|1.702689|1.937612|2.604737|2.342012|10.305206|9.271900|0.190537|6.257855|4.490707|0.302157|0.298768|0.500000| |3.982602|5.124546|0.169653|5.783742|6.168047|6.015030|5.461706|9.774114|8.910245|17.723795|8.922903|5.658279|4.945198|5.635835|31.654863|32.977777|3.416949|2.896204|5.198931|3.341086|2.122865|2.047358|1.792208|1.645809|1.687820|1.893849|2.093276|2.713292|2.565587|11.580654|5.554187|0.103714|3.232434|4.376229|0.116833|0.098651|0.095188|0.500000| |3.116954|3.482135|0.113604|3.546659|4.016082|3.967835|3.463168|5.671005|5.650522|8.909898|17.757398|8.920472|5.635258|4.945658|53.957378|23.920075|2.586336|2.358824|4.411397|2.766606|1.825781|1.818967|1.625577|1.484513|1.491045|1.634204|1.851216|2.379997|2.292395|10.652325|3.919228|0.073373|2.515199|2.973362|0.095045|0.082059|0.075169|0.214571|0.500000| |3.538195|3.314172|0.095748|3.450134|3.953995|3.994389|3.542411|5.669668|5.652070|4.947545|5.635139|8.919845|17.758298|8.913234|53.934517|25.417594|2.706618|2.494209|4.725213|2.900119|1.914580|1.924802|1.713225|1.550482|1.547905|1.697785|1.907164|2.475078|2.329529|11.113580|3.568555|0.069735|2.367588|2.409384|0.122070|0.090540|0.088880|0.107450|0.124160|0.500000| |5.021123|4.641935|0.123066|5.398634|5.953045|6.103736|5.777801|9.763969|8.911100|5.636358|4.943523|5.656506|8.919829|17.729275|31.645582|37.131431|3.700483|3.150382|5.718726|3.577131|2.261944|2.197589|1.908461|1.734479|1.769104|1.991750|2.172533|2.853557|2.614895|12.164019|4.678842|0.094272|2.941463|2.999737|0.184727|0.114961|0.129606|0.124064|0.107419|0.214565|0.500000| |2.864588|3.090265|0.078002|4.059249|6.388237|9.416810|6.711846|6.231430|3.713290|3.143151|2.660458|2.565787|2.849237|3.465437|16.988251|56.251221|17.614472|8.833767|10.981774|9.644362|4.703715|3.868994|3.052265|2.795428|3.076988|3.926588|3.633566|4.878129|4.134743|17.948150|3.861999|0.086755|2.372912|2.687452|0.081769|0.068456|0.083171|0.086367|0.066390|0.073427|0.103661|0.500000| |2.705822|3.077022|0.079720|4.051558|6.381718|9.414262|6.694553|6.215375|3.710871|3.337556|2.777202|2.567809|2.726976|3.249253|17.004961|56.245179|17.614468|8.837287|11.000511|9.627313|4.702545|3.852391|3.043597|2.796217|3.087185|3.942434|3.655928|4.806693|4.231066|17.920883|3.934404|0.087322|2.374776|2.892548|0.076049|0.065481|0.076254|0.096317|0.070657|0.068776|0.091522|0.302346|0.500000| |2.103567|2.263221|0.058942|2.750038|4.207037|5.342848|3.783679|4.050808|2.609286|2.381200|2.106679|2.025181|2.161049|2.458960|14.052306|32.079660|7.763969|9.472231|10.872315|26.042342|9.334804|5.736371|4.293897|4.067369|4.938287|7.685288|5.485451|7.312087|5.899388|23.930097|2.952595|0.065222|1.880208|2.139112|0.059285|0.052249|0.060378|0.066962|0.054501|0.056694|0.071034|0.212512|0.211645|0.500000| |1.767118|1.857108|0.050105|2.166056|3.050409|3.621963|2.862413|3.335813|2.368047|2.232514|2.092732|2.072486|2.182178|2.340062|14.939118|26.878517|4.430844|6.839966|15.071095|9.471992|8.892757|17.829673|8.966463|5.636153|4.977684|5.661244|4.905793|5.753603|5.680734|31.859494|2.348320|0.049886|1.529808|1.709224|0.051346|0.044733|0.049383|0.061055|0.054796|0.058600|0.066307|0.110156|0.109268|0.142661|0.500000| |1.444784|1.502971|0.040734|1.700707|2.392145|2.734066|2.101951|2.540818|1.819482|1.744544|1.667814|1.660181|1.726276|1.810567|12.346065|18.127109|2.886908|3.748288|7.233520|5.646722|5.660197|8.969678|17.758376|8.982277|5.701485|4.990952|5.617146|6.129605|6.878532|55.032377|1.933124|0.040908|1.285125|1.412606|0.041634|0.037160|0.040469|0.047962|0.044403|0.047005|0.051203|0.075581|0.075238|0.098170|0.217180|0.500000| |1.695536|1.797163|0.047306|2.087337|3.133444|3.696121|2.613902|2.995323|1.993558|1.864879|1.696813|1.644065|1.731143|1.909751|11.759416|21.028714|4.046716|4.818045|7.081541|9.970294|8.877305|5.646253|4.991671|5.657318|9.020463|17.759591|10.180484|14.067855|9.411000|31.430656|2.389824|0.052299|1.566226|1.744683|0.047503|0.043012|0.048665|0.052526|0.044663|0.046117|0.054858|0.112991|0.113762|0.233884|0.123905|0.108239|0.500000| |6.265672|6.873871|0.188617|4.560760|5.514799|4.299253|3.018295|4.875436|3.314549|3.202873|2.818463|2.600972|2.652232|2.967563|17.744430|16.967316|2.153704|1.846382|3.150939|2.319660|1.513682|1.426812|1.293709|1.237925|1.295025|1.428657|1.673993|2.234812|2.056787|8.936397|12.291753|0.180227|17.645656|6.935137|0.133084|0.208455|0.151232|0.091377|0.073559|0.067121|0.079994|0.060741|0.061175|0.048730|0.040816|0.034436|0.040876|0.500000| |4.857392|5.527208|0.137829|4.265361|5.761391|4.437847|2.946893|4.481344|2.897404|2.765953|2.408320|2.223000|2.284642|2.584732|15.284786|16.503645|2.184688|1.861120|3.122910|2.375877|1.546619|1.439535|1.306791|1.262045|1.333944|1.476451|1.738516|2.338089|2.132481|9.093607|12.379692|0.220429|17.654770|7.380904|0.106259|0.141345|0.133532|0.080421|0.063193|0.058300|0.071105|0.062286|0.063099|0.050637|0.040758|0.034551|0.042719|0.299685|0.500000| |7.310795|6.759351|0.153767|4.816042|6.211219|4.709344|3.179566|4.975318|3.223588|2.937143|2.561743|2.432516|2.581198|2.968717|16.527908|17.574661|2.281546|1.934767|3.260426|2.446678|1.587175|1.482604|1.341096|1.287987|1.356429|1.503963|1.757206|2.365946|2.144907|9.264530|12.249396|0.224358|17.696010|5.635644|0.143978|0.224559|0.214305|0.081979|0.065591|0.066361|0.083684|0.066071|0.064279|0.051891|0.042200|0.035521|0.043321|0.298787|0.300706|0.500000| |4.705218|6.838621|0.218444|5.281363|6.374704|5.007589|3.530507|5.697414|3.786885|3.950595|3.295394|2.820826|2.752687|3.104013|18.813890|19.522879|2.453737|2.077318|3.535028|2.585813|1.671527|1.569339|1.412142|1.346261|1.411219|1.567645|1.814526|2.404787|2.233715|9.641590|12.314100|0.181566|7.149067|17.642849|0.111537|0.129031|0.113540|0.124549|0.088085|0.067394|0.080221|0.066987|0.071916|0.054272|0.044987|0.037462|0.044838|0.210135|0.183951|0.143631|0.500000| |4.587099|7.176941|0.197055|7.174470|9.432674|7.081669|4.727736|7.319388|4.344577|4.371543|3.411220|2.887448|2.873798|3.383191|18.748920|24.399730|3.095189|2.518166|4.197434|3.107092|1.962353|1.813180|1.608494|1.530258|1.619570|1.828623|2.069534|2.747046|2.528595|10.800480|12.276108|0.223569|5.635099|17.695066|0.111591|0.114207|0.116245|0.143699|0.089106|0.069605|0.088138|0.083712|0.093512|0.065869|0.051885|0.042259|0.052652|0.142519|0.147877|0.126078|0.297923|0.500000| 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