Version2.1 2021-01-07T10:47:44Z 10.1021/jm300687e Gaussian16 RevisionB.01 PWARBURT 23-Dec-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE C[C@@H]1CN(C[C@@H](O1)C)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(s3)CN(CC4)C(=O)OC C12373942 RHF 6-31G(d) (6D,7F) C[C@@H]1CN(C[C@@H](O1)C)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(s3)CN(CC4)C(=O)OC C01[X(C21H26N4O6S2)] 171 C1 555 COC(=O)N1CCc2c(C1)sc(n2)NC(=O)c1ccc(cc1)S(=O)(=O)N1C[C@H](C)O[C@@H](C1)C COC(=O)N1CCc2c(C1)sc(n2)NC(=O)c1ccc(cc1)S(=O)(=O)N1C[C@H](C)O[C@@H](C1)C COC(=O)N1CCc2nc(NC(=O)c3ccc(cc3)[S](=O)(=O)N4C[C@H](C)O[C@H](C)C4)sc2C1 InChIKey=NNJRXNJEUBBKEZ-OKILXGFUSA-N InChI=1S/C21H26N4O6S2/c1-13-10-25(11-14(2)31-13)33(28,29)16-6-4-15(5-7-16)19(26)23-20-22-17-8-9-24(21(27)30-3)12-18(17)32-20/h4-7,13-14H,8-12H2,1-3H3,(H,22,23,26)/t13-,14+ InChI=1/C21H26N4O6S2/c1-13-10-25(11-14(2)31-13)33(28,29)16-6-4-15(5-7-16)19(26)23-20-22-17-8-9-24(21(27)30-3)12-18(17)32-20/h4-7,13-14H,8-12H2,1-3H3,(H,22,23,26)/t13-,14+/f/h23H C[C@@H]1CN(C[C@@H](O1)C)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(s3)CN(CC4)C(=O)OC C01[X(C21H26N4O6S2)] 171 C01 555 COC(=O)N1CCc2c(C1)sc(n2)NC(=O)c1ccc(cc1)S(=O)(=O)N1C[C@H](C)O[C@@H](C1)C COC(=O)N1CC[C]2=C(C1)S[C](=[N]2)NC(=O)[C]1[CH][CH][C]([CH][CH]1)S(=O)(=O)N1C[C@H](C)O[C@@H](C1)C COC(=O)N1CCc2nc(NC(=O)[C]3[CH][CH][C]([CH][CH]3)[S](=O)(=O)N4C[C@H](C)O[C@H](C)C4)sc2C1 InChIKey=NNJRXNJEUBBKEZ-OKILXGFUSA-N InChI=1S/C21H26N4O6S2/c1-13-10-25(11-14(2)31-13)33(28,29)16-6-4-15(5-7-16)19(26)23-20-22-17-8-9-24(21(27)30-3)12-18(17)32-20/h4-7,13-14H,8-12H2,1-3H3,(H,22,23,26)/t13-,14+ InChI=1/C21H26N4O6S2/c1-13-10-25(11-14(2)31-13)33(28,29)16-6-4-15(5-7-16)19(26)23-20-22-17-8-9-24(21(27)30-3)12-18(17)32-20/h4-7,13-14H,8-12H2,1-3H3,(H,22,23,26)/t13-,14+/f/h23H 3610.3178332063 -2272.3390025 1-A 36686.2667 130 425 555 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MUNgauss RevisionA2.0 retrievium 07-Jan-2021 DUDE C[C@@H]1CN(C[C@@H](O1)C)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(s3)CN(CC4)C(=O)OC C12373942 RHF 6-31G(d) (6D,10F) C1 494.129378 |X|Y|Z| 34.090997 41.338727 183.889060
63.755486 24 6 7 8 16 17 4 1 2
|36.858105| |12.553212|36.858105| |8.870801|17.492537|0.500000| |7.546953|12.498478|0.248253|36.858105| |5.025357|7.846240|0.197834|12.992061|53.358707| |4.506207|6.692081|0.164210|7.790719|17.625972|36.858105| |5.208377|8.082798|0.203030|6.707828|10.691390|12.507942|36.858105| |4.796367|7.316444|0.222700|5.930569|9.715301|8.941855|17.492319|0.500000| |8.080105|13.582205|0.259685|7.946503|9.356240|7.935224|13.566249|0.259646|73.516695| |4.055423|5.209888|0.133245|4.511090|6.841593|7.553236|12.553809|0.246410|14.360708|36.858105| |3.694938|4.827027|0.128119|7.216306|15.730748|7.184080|4.822910|0.128122|7.704976|3.688589|388.023441| |3.047112|3.891871|0.106109|5.009383|10.485337|6.733124|4.528243|0.122936|6.726726|3.690368|94.720884|73.516695| |3.564516|4.296890|0.108620|6.495058|10.205445|5.529499|3.991773|0.102124|6.854633|3.227645|94.529369|13.673035|73.516695| |3.465882|4.319540|0.124920|5.821000|9.707936|4.782841|3.858631|0.110632|6.466100|3.010018|76.316870|12.978331|13.082581|36.858105| |3.213737|4.020278|0.124274|4.800083|8.067756|4.387074|3.780168|0.115284|6.154860|2.974511|49.479709|10.961021|8.762780|13.709659|36.858105| |2.855980|3.371850|0.105258|3.807247|5.788237|3.366288|3.066302|0.093580|5.162568|2.505513|33.697403|7.688617|6.805782|7.975811|13.822585|36.858105| |2.714623|3.064947|0.092872|3.508534|5.014584|2.928194|2.668804|0.079014|4.643626|2.217262|29.887059|6.576371|6.587042|6.906916|7.931473|13.674355|36.858105| |2.861471|3.192345|0.093161|3.853636|5.347118|3.040095|2.698145|0.077531|4.775714|2.233700|33.666636|6.950092|7.936854|7.976812|6.857696|7.915991|13.744012|36.858105| |3.231390|3.737409|0.105865|4.916623|7.009796|3.736797|3.152535|0.088724|5.541072|2.550456|49.563591|9.093801|11.755652|13.792432|7.891572|6.852999|7.922546|13.725108|36.858105| |2.349267|2.565080|0.077724|2.809627|3.926617|2.403912|2.255963|0.066882|3.959041|1.924806|22.457954|5.133125|5.119844|4.474304|5.081004|7.714452|12.692378|7.509696|5.010277|36.858105| |2.279903|2.480254|0.076410|2.627345|3.668396|2.291555|2.201765|0.066185|3.858845|1.891502|20.198641|4.699460|4.549351|3.838454|4.550657|6.747478|8.067180|5.326866|4.023577|15.917780|73.516695| |2.110211|2.258496|0.066860|2.488815|3.439733|2.138957|1.996355|0.058199|3.525685|1.730368|19.983704|4.593775|4.743271|3.778962|3.974727|5.242856|7.841270|6.538902|4.449207|13.970575|15.092304|53.358707| |1.869083|1.968725|0.058077|2.124936|2.915819|1.856977|1.757274|0.051143|3.114275|1.547653|16.595319|3.877464|3.980545|2.966792|3.119472|3.909647|5.064799|4.458236|3.372148|7.766293|11.982442|18.725846|36.858105| |1.720425|1.796237|0.052288|1.945757|2.660389|1.710989|1.612982|0.046483|2.864976|1.434025|15.240737|3.576853|3.732098|2.642881|2.699034|3.222360|4.041017|3.843614|3.029250|5.317353|8.281026|11.277961|14.948104|53.358707| |1.564084|1.619635|0.047157|1.727167|2.354730|1.537003|1.465124|0.042254|2.606243|1.315854|13.264203|3.142542|3.245520|2.239583|2.305644|2.705101|3.219819|3.037967|2.498455|4.111046|6.958372|7.423587|8.729881|18.771422|36.858105| |1.560196|1.615525|0.047464|1.699230|2.317444|1.519149|1.463757|0.042528|2.602517|1.316025|12.853400|3.056206|3.104245|2.169223|2.280724|2.705575|3.142221|2.861072|2.368809|4.118527|7.493236|6.854815|7.905435|11.257522|14.255991|36.858105| |1.767270|1.850682|0.055201|1.942715|2.661008|1.723078|1.664388|0.048900|2.950721|1.478083|14.687343|3.472851|3.476840|2.557452|2.770209|3.447598|4.061155|3.456391|2.771133|5.965567|11.885090|9.368819|10.953754|10.097841|7.517224|10.929581|388.023441| |1.416406|1.457255|0.042739|1.514907|2.062889|1.370175|1.331523|0.038663|2.369300|1.209078|11.309119|2.709109|2.734400|1.865433|1.961818|2.276289|2.550414|2.344281|2.002861|3.176394|5.924358|4.931063|4.884584|6.931033|7.539995|12.673030|47.155994|36.858105| |1.311131|1.344912|0.039105|1.404208|1.912356|1.277102|1.235887|0.035651|2.198964|1.128866|10.543770|2.534496|2.575657|1.714969|1.778373|2.024827|2.262353|2.132206|1.848041|2.718753|4.910791|4.270415|4.062079|6.262736|6.891123|7.931503|33.254914|13.094375|53.358707| |1.330887|1.358730|0.039247|1.429372|1.935032|1.286960|1.238853|0.035520|2.214190|1.129614|10.734724|2.561926|2.653461|1.743691|1.778625|2.009494|2.282294|2.205483|1.908586|2.705150|4.733592|4.372647|4.132428|6.904343|7.729669|6.903203|30.246286|7.671119|17.792867|36.858105| |1.420742|1.461153|0.042149|1.556957|2.117758|1.396619|1.330783|0.038112|2.370851|1.206141|11.927934|2.840209|2.956026|1.963190|1.990833|2.266892|2.635374|2.566031|2.182055|3.155961|5.333653|5.396051|5.297409|10.302771|12.713845|7.667915|33.959560|6.322783|10.556654|12.470649|36.858105| |1.203839|1.234294|0.035819|1.282721|1.752106|1.180728|1.145842|0.033028|2.033831|1.054204|9.625285|2.331425|2.350532|1.544436|1.603074|1.802914|1.975958|1.866483|1.645754|2.319060|4.214104|3.542856|3.204686|4.799411|4.710183|5.224279|25.938711|7.722647|19.139215|7.852133|5.361937|36.858105| |1.135930|1.161880|0.033547|1.209228|1.650658|1.116769|1.082055|0.031062|1.921514|0.999548|9.082666|2.203875|2.231596|1.443262|1.486150|1.652349|1.805207|1.727572|1.538837|2.077893|3.729632|3.169967|2.793648|4.241292|3.989921|4.115626|21.563046|5.315476|11.457291|6.882094|4.839947|15.909671|73.516695| |1.189080|1.222117|0.035623|1.261624|1.728913|1.169778|1.141071|0.033032|2.019883|1.052037|9.437670|2.296653|2.286816|1.512131|1.586276|1.787410|1.930409|1.798810|1.592744|2.267890|4.210724|3.375910|3.007027|4.297336|4.022307|4.751678|25.542548|7.193246|11.636142|5.316530|4.154245|14.340486|15.259491|73.516695| |1.095650|1.125173|0.032712|1.157715|1.589498|1.083842|1.059471|0.030624|1.872241|0.983283|8.652179|2.117553|2.098438|1.369626|1.434479|1.596921|1.702207|1.595050|1.431856|1.958124|3.626922|2.870869|2.473649|3.513448|3.129012|3.521109|20.344249|4.689053|7.342591|4.005675|3.280998|8.165991|12.921983|23.907782|36.858105| |17.568695|8.851817|0.173503|6.861085|6.345783|4.350263|4.810755|0.117047|12.903371|3.954960|25.274162|5.236367|6.385341|3.204712|2.902946|2.574959|2.479780|2.660109|3.035851|2.154922|3.686068|2.679863|1.752924|2.220960|1.485780|1.472237|11.709996|1.340155|1.701490|1.274850|1.361425|1.150906|1.939559|2.014670|1.047293|0.500000| |17.586948|8.889959|0.213635|5.508533|5.679438|3.962513|4.864683|0.128457|13.050526|4.010504|22.425482|4.813514|5.335236|3.002430|2.882813|2.612257|2.466645|2.540558|2.794141|2.182232|3.827824|2.668679|1.758758|2.203351|1.486187|1.493714|12.013063|1.367532|1.720884|1.276924|1.352617|1.165700|1.955079|2.055902|1.068919|0.301321|0.500000| |17.551341|8.826939|0.212398|6.835770|6.252429|3.898155|4.240943|0.113208|10.233649|3.362149|25.559154|5.191237|6.258172|3.571526|3.290797|2.999750|2.924838|3.115331|3.456843|2.539728|4.362835|3.106167|2.015004|2.516629|1.674801|1.669430|13.497666|1.507980|1.893659|1.417419|1.514775|1.270171|2.126089|2.223968|1.147183|0.300027|0.300659|0.500000| |6.986309|8.833703|0.174210|17.542449|12.289888|6.938381|5.806131|0.134949|12.499225|4.297460|45.363902|8.169245|12.110285|4.853279|3.942897|3.230896|3.071559|3.447985|4.377632|2.514413|4.160034|3.110443|1.973522|2.496114|1.634206|1.596890|12.777790|1.430147|1.819636|1.368519|1.489274|1.224886|2.063477|2.134219|1.105190|0.208721|0.142055|0.172755|0.500000| |6.784727|8.879625|0.218197|17.604076|12.401672|5.649108|5.018511|0.133334|10.187827|3.636204|49.062135|8.275224|11.476335|6.753530|5.306480|4.311377|4.115221|4.686440|6.097260|3.214608|5.252753|3.848726|2.374363|2.938118|1.895023|1.858047|15.234092|1.639560|2.059513|1.546694|1.694418|1.371598|2.291544|2.389607|1.225700|0.165995|0.139870|0.200732|0.300936|0.500000| |4.307096|5.814493|0.134931|6.950606|12.255736|17.514222|8.863426|0.174455|12.543369|7.001336|45.057075|10.499350|10.053507|4.161909|3.685853|2.930031|2.636658|2.797599|3.439521|2.194152|3.696611|2.708529|1.740926|2.207759|1.460979|1.435933|11.439723|1.299313|1.659580|1.234718|1.338901|1.129750|1.907927|1.983419|1.036340|0.122984|0.104569|0.102949|0.203961|0.141832|0.500000| |3.634219|5.012061|0.132962|5.663353|12.430895|17.673220|8.848676|0.217305|10.167937|6.760659|48.989420|14.226014|8.999117|4.668959|4.476462|3.401942|2.898028|2.951274|3.578140|2.387183|4.057649|2.888636|1.845154|2.313702|1.528507|1.512008|12.195784|1.365008|1.733088|1.278084|1.388979|1.180460|1.984943|2.084027|1.088291|0.097117|0.091641|0.090232|0.142082|0.127144|0.300366|0.500000| |3.362278|4.242126|0.113203|3.903221|6.255825|6.847175|8.830567|0.212395|10.232502|17.554857|25.508233|6.758225|5.490008|2.931311|2.948405|2.480259|2.173026|2.168112|2.462741|1.891925|3.311790|2.316153|1.524583|1.923916|1.298555|1.299377|10.368815|1.195316|1.520666|1.114683|1.191114|1.046064|1.763890|1.859440|0.979646|0.090788|0.092007|0.080380|0.102819|0.090277|0.172917|0.199976|0.500000| |4.010731|4.868304|0.128577|3.966844|5.681926|5.511155|8.889018|0.213657|13.049843|17.585585|22.402931|5.535782|4.973576|2.700236|2.712297|2.344088|2.085769|2.081863|2.330009|1.838533|3.245877|2.249746|1.490169|1.877975|1.273982|1.280956|10.226602|1.183143|1.501174|1.100665|1.168456|1.031984|1.738634|1.835911|0.966753|0.107039|0.116220|0.092020|0.104348|0.091749|0.142325|0.139475|0.300560|0.500000| |3.955239|4.810469|0.117029|4.351446|6.342753|6.863323|8.851699|0.173500|12.900570|17.568395|25.218376|6.240153|5.771608|2.833517|2.722292|2.309044|2.083678|2.133963|2.450868|1.813586|3.144252|2.245771|1.479881|1.880446|1.268319|1.262073|9.994748|1.160733|1.482658|1.094867|1.169319|1.018198|1.721966|1.800640|0.947943|0.112866|0.107077|0.090779|0.122577|0.097084|0.209256|0.165607|0.300092|0.301329|0.500000| |3.185285|4.105616|0.128901|4.687174|8.484215|4.908642|4.251575|0.135011|6.555292|3.322300|47.279154|11.888944|8.044606|8.901341|17.752989|8.926920|5.639027|4.946919|5.632211|4.138601|6.975615|4.531560|2.725818|3.247439|2.082806|2.080592|17.777362|1.820632|2.252584|1.642942|1.817665|1.506973|2.489417|2.669818|1.368764|0.079735|0.080679|0.087948|0.106538|0.133898|0.109895|0.146264|0.093324|0.083478|0.082448|0.500000| |2.632590|3.075346|0.097374|3.312405|5.013295|3.065195|2.883126|0.089660|4.816740|2.402084|27.800830|6.664920|5.697503|5.656159|8.922527|17.760311|8.932774|5.649229|4.945140|7.243344|13.356859|6.641550|3.843588|4.255087|2.688386|2.759645|25.590304|2.344645|2.804090|2.008767|2.239704|1.842987|2.983285|3.288707|1.653572|0.065744|0.068387|0.076184|0.078837|0.101048|0.074075|0.087202|0.066663|0.063234|0.060967|0.214164|0.500000| |2.651343|2.854648|0.082041|3.384144|4.542681|2.664918|2.396474|0.068104|4.306635|2.021019|27.885679|5.865248|6.988386|5.677416|4.945477|5.623875|8.870039|17.729867|8.965597|6.859918|8.689947|9.700203|4.886288|5.927936|3.341579|3.055535|25.530449|2.469259|3.081994|2.390185|2.826224|1.960933|3.234208|3.315987|1.644270|0.069377|0.065738|0.081019|0.086811|0.113222|0.069558|0.071500|0.054345|0.052696|0.054182|0.107446|0.123989|0.500000| |3.220392|3.620748|0.098471|4.891883|6.643744|3.624328|3.025220|0.082730|5.415107|2.482120|47.409997|8.529433|13.819290|8.943793|5.633302|4.945398|5.634386|8.878674|17.764744|4.071873|5.968940|5.232347|3.036769|3.838040|2.348666|2.201946|17.787039|1.879514|2.391745|1.834614|2.093802|1.570881|2.631821|2.686929|1.364640|0.086489|0.076480|0.095733|0.128947|0.166932|0.096362|0.094817|0.066123|0.062787|0.067562|0.124172|0.107455|0.215556|0.500000| |2.099264|2.248022|0.065588|2.526504|3.498688|2.167031|1.992304|0.057455|3.516595|1.728365|20.893018|4.778158|5.065714|3.942972|3.948619|4.933943|7.404585|7.288621|4.874937|9.274260|10.840620|26.037148|9.538577|10.744178|5.054328|4.375779|37.398244|3.253139|3.997237|3.092337|3.905105|2.462996|3.987729|4.119269|1.992662|0.054960|0.053737|0.062915|0.065162|0.079869|0.056478|0.059711|0.047221|0.045568|0.046088|0.091053|0.122040|0.243271|0.119350|0.500000| |1.428087|1.457814|0.042807|1.504080|2.031129|1.350079|1.321052|0.038364|2.365191|1.199937|11.019526|2.625033|2.667684|1.810156|1.899981|2.193454|2.446822|2.259258|1.940726|3.017222|5.696116|4.569166|4.358058|5.992932|5.961751|8.889545|42.403598|17.494925|12.330844|6.498478|5.173557|6.411584|8.380775|11.115776|4.341872|0.037470|0.038445|0.042388|0.039441|0.045257|0.035576|0.037188|0.032836|0.032743|0.032000|0.049089|0.062722|0.066105|0.050730|0.083572|0.500000| |1.381089|1.428664|0.042043|1.478891|2.028608|1.354705|1.319747|0.038474|2.335185|1.202065|11.094067|2.680641|2.661479|1.823960|1.940773|2.253895|2.475050|2.241818|1.930975|3.068199|5.854925|4.612520|4.400112|5.963450|5.852652|8.924576|44.000857|17.672378|12.496007|5.663359|4.982537|7.302187|8.919096|14.867532|5.292749|0.036239|0.037167|0.040621|0.038683|0.044206|0.035587|0.037667|0.033134|0.032715|0.031964|0.050464|0.065472|0.064490|0.050070|0.084158|0.302917|0.500000| |1.364167|1.382302|0.039918|1.449015|1.944409|1.290547|1.247332|0.035729|2.243684|1.135655|10.711577|2.537001|2.655781|1.739063|1.766545|1.991887|2.270325|2.208320|1.910975|2.683541|4.709221|4.299145|4.009416|6.500232|6.788803|6.374132|29.647670|6.987783|12.451160|17.514810|8.862074|6.201892|9.833907|8.230634|3.589083|0.036275|0.036391|0.040561|0.038560|0.043698|0.034420|0.035420|0.031007|0.030805|0.030598|0.045256|0.055106|0.066889|0.051191|0.084044|0.190913|0.141296|0.500000| |1.245300|1.269276|0.036505|1.334682|1.808624|1.210273|1.164551|0.033285|2.079864|1.067556|10.036160|2.405694|2.491817|1.610392|1.634572|1.823744|2.048480|1.997966|1.755035|2.372454|4.138545|3.773201|3.413469|5.601820|5.597177|5.026756|24.536468|5.646290|12.569388|17.701042|8.795487|7.741631|14.743506|8.976515|4.050051|0.033283|0.033232|0.036700|0.035673|0.039905|0.032381|0.033426|0.029299|0.028899|0.028820|0.042178|0.050555|0.059913|0.047208|0.075377|0.138938|0.128272|0.301899|0.500000| |1.361443|1.408189|0.040541|1.504697|2.064663|1.368504|1.298642|0.037164|2.299353|1.181499|11.709046|2.816111|2.899455|1.914256|1.943476|2.198582|2.524323|2.455933|2.111918|2.972666|5.008626|5.017200|4.716572|8.818310|8.937267|6.171637|29.998387|5.369112|9.165576|8.814114|17.534591|5.226038|8.736602|7.256105|3.311744|0.036334|0.036003|0.040068|0.040057|0.045214|0.036488|0.038012|0.032546|0.031728|0.031837|0.049533|0.060476|0.074276|0.056345|0.102703|0.120382|0.127858|0.173922|0.217618|0.500000| |1.442614|1.475842|0.042320|1.581050|2.136080|1.404817|1.334317|0.038010|2.388509|1.208202|12.068991|2.852575|3.026164|1.978266|1.974429|2.223895|2.609181|2.611262|2.228610|3.051295|5.049214|5.246296|4.880548|9.569343|8.950087|5.817958|29.466562|4.854869|7.664366|8.835850|17.555326|4.277038|7.220263|6.088489|2.818412|0.038564|0.038008|0.042860|0.042244|0.047950|0.037584|0.038645|0.033044|0.032463|0.032663|0.049852|0.060158|0.081480|0.060168|0.109096|0.119537|0.109830|0.219889|0.204891|0.302567|0.500000| |1.091937|1.123068|0.032747|1.150199|1.582166|1.081778|1.061459|0.030772|1.872574|0.986590|8.572429|2.103691|2.068651|1.355454|1.428942|1.591419|1.680233|1.562642|1.406759|1.930682|3.619382|2.786729|2.375714|3.299794|2.875493|3.294080|19.896989|4.297087|6.136090|3.422583|2.909088|5.951994|9.233053|16.949752|17.656082|0.028931|0.029681|0.031697|0.030428|0.033746|0.028669|0.030215|0.027337|0.027000|0.026360|0.038060|0.046121|0.044407|0.037112|0.053387|0.113054|0.140650|0.087259|0.093754|0.081115|0.070162|0.500000| |1.067527|1.099466|0.031888|1.135487|1.565162|1.069206|1.041199|0.030048|1.834329|0.968014|8.563396|2.104876|2.079711|1.351295|1.412326|1.566157|1.666843|1.567394|1.411905|1.903749|3.494100|2.802426|2.397041|3.440233|3.029583|3.298653|19.171697|4.156427|6.686332|3.821962|3.237325|7.225940|12.864341|16.433416|17.642698|0.028411|0.028880|0.030969|0.030167|0.033327|0.028441|0.029900|0.026849|0.026381|0.025954|0.037470|0.044944|0.044856|0.037447|0.054527|0.103802|0.128483|0.092815|0.110310|0.093958|0.077360|0.298593|0.500000| |1.060856|1.083926|0.031432|1.113248|1.521538|1.039042|1.017539|0.029338|1.804499|0.946142|8.257421|2.015348|2.011340|1.300450|1.354276|1.498518|1.598675|1.510582|1.362090|1.823929|3.362569|2.671898|2.283263|3.259705|2.882353|3.185749|18.507003|4.172667|6.660886|3.851737|3.081521|7.227931|12.940071|16.435432|17.644287|0.028225|0.028784|0.030878|0.029606|0.032722|0.027670|0.028905|0.026136|0.025875|0.025390|0.035906|0.042885|0.043403|0.036239|0.051797|0.112391|0.123415|0.098689|0.111263|0.085187|0.075155|0.298551|0.300359|0.500000|
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