Version2.4 2021-04-30T16:25:51Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 02-Nov-2018 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE C[C@]1(CC[NH2+]C1)C(=O)Nc2cccc(c2)S(=O)(=O)N C62888645 RHF 6-31G(d) (6D,7F) C[C@]1(CC[NH2+]C1)C(=O)Nc2cccc(c2)S(=O)(=O)N C01[X(C12H18N3O3S1)] 105 C1 325 O=C([C@@]1(C)C[NH2+]CC1)Nc1cccc(c1)S(=O)(=O)N O=C([C@@]1(C)C[NH2+]CC1)Nc1cccc(c1)S(=O)(=O)N C[C@]1(CC[NH2+]C1)C(=O)Nc2cccc(c2)[S](N)(=O)=O InChIKey=ARDVFETYKLRLEJ-GFCCVEGCSA-O InChI=1S/C12H17N3O3S/c1-12(5-6-14-8-12)11(16)15-9-3-2-4-10(7-9)19(13,17)18/h2-4,7,14H,5-6,8H2,1H3,(H,15,16)(H2,13,17,18)/p+1/t12-/m1/s1 InChI=1/C12H17N3O3S/c1-12(5-6-14-8-12)11(16)15-9-3-2-4-10(7-9)19(13,17)18/h2-4,7,14H,5-6,8H2,1H3,(H,15,16)(H2,13,17,18)/p+1/t12-/m1/s1/fC12H18N3O3S/h14-15H,13H2/q+1 C[C@]1(CC[NH2+]C1)C(=O)Nc2cccc(c2)S(=O)(=O)N C01[X(C12H18N3O3S1)] 105 C01 325 O=C([C@@]1(C)C[NH2+]CC1)Nc1cccc(c1)S(=O)(=O)N O=[C]([NH][C]1[CH][CH][CH][C]([CH]1)S(=O)(=O)N)[C@@]1(C)C[NH2]CC1 C[C@]1(CC[NH2]C1)C(=O)N[C]2[CH][CH][CH][C]([CH]2)[S](N)(=O)=O InChIKey=PLKSUGIDKJIWRL-GFCCVEGCSA-N InChI=1S/C12H18N3O3S/c1-12(5-6-14-8-12)11(16)15-9-3-2-4-10(7-9)19(13,17)18/h2-4,7H,5-6,8,14H2,1H3,(H,15,16)(H2,13,17,18)/t12-/m1/s1 InChI=1/C12H18N3O3S/c1-12(5-6-14-8-12)11(16)15-9-3-2-4-10(7-9)19(13,17)18/h2-4,7H,5-6,8,14H2,1H3,(H,15,16)(H2,13,17,18)/t12-/m1/s1/f/h15H,13H2 1655.2664738962 -1250.0902075 1-A 7090.0207 75 250 325 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -92.28764 -20.67784 -20.63198 -20.62772 -15.84613 -15.73852 -15.67608 -11.50379 -11.45400 -11.44933 -11.42405 -11.40084 -11.39436 -11.37639 -11.36148 -11.35282 -11.35212 -11.34729 -11.34104 -9.25946 -6.94585 -6.94556 -6.94436 -1.55632 -1.55099 -1.48868 -1.43117 -1.39236 -1.30058 -1.27941 -1.26259 -1.19374 -1.14927 -1.13510 -1.10945 -1.03750 -1.01369 -1.00089 -0.97365 -0.94021 -0.91895 -0.90832 -0.89377 -0.85583 -0.83461 -0.80482 -0.80203 -0.79263 -0.78350 -0.77217 -0.76088 -0.75873 -0.75076 -0.74229 -0.72090 -0.72033 -0.71137 -0.70466 -0.70238 -0.69381 -0.66947 -0.66157 -0.64521 -0.63861 -0.62867 -0.62525 -0.60944 -0.57716 -0.56730 -0.56048 -0.55204 -0.54136 -0.53139 -0.45097 -0.43752 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| 0.00739 0.02578 0.03210 0.05998 0.07055 0.07674 0.11278 0.12692 0.12975 0.13315 0.13796 0.15207 0.15313 0.15774 0.16342 0.18286 0.18975 0.19786 0.20815 0.20903 0.21652 0.21936 0.23221 0.23277 0.23881 0.24748 0.25891 0.26267 0.27409 0.28168 0.29135 0.30231 0.32124 0.35387 0.35955 0.36580 0.38137 0.40823 0.42317 0.46528 0.48017 0.48618 0.50314 0.54998 0.55149 0.56221 0.57020 0.58743 0.60387 0.61614 0.62631 0.64356 0.65171 0.66861 0.68426 0.69206 0.70249 0.70802 0.71775 0.73058 0.73515 0.74418 0.75040 0.75633 0.75801 0.76915 0.77492 0.78572 0.79399 0.80902 0.81800 0.82804 0.84060 0.86619 0.87019 0.87732 0.88659 0.92132 0.92405 0.94004 0.94396 0.94547 0.95707 0.96525 0.97594 0.98144 0.98553 0.99113 0.99591 1.00691 1.00950 1.01234 1.01779 1.02182 1.02833 1.03517 1.04699 1.05069 1.05419 1.07067 1.07682 1.08414 1.09208 1.10353 1.11382 1.12311 1.12924 1.13326 1.14907 1.16428 1.18424 1.20464 1.22150 1.24338 1.25030 1.25170 1.28935 1.29631 1.30883 1.31789 1.33886 1.35611 1.38588 1.39603 1.41728 1.43549 1.43907 1.46141 1.47048 1.48112 1.51462 1.53703 1.54278 1.59082 1.59852 1.60714 1.62162 1.63664 1.64287 1.65127 1.65410 1.68381 1.71095 1.74195 1.75841 1.80243 1.82025 1.84557 1.86429 1.88084 1.89918 1.93505 1.93724 1.95856 1.97262 1.97828 1.98124 1.98967 2.00495 2.01799 2.03513 2.04458 2.05099 2.06172 2.06549 2.09954 2.10239 2.11184 2.12762 2.13413 2.14607 2.16565 2.18126 2.19910 2.20681 2.21195 2.22341 2.22454 2.27990 2.28807 2.29046 2.31163 2.31972 2.33974 2.35852 2.36649 2.36864 2.37457 2.39145 2.41498 2.42486 2.43450 2.43705 2.46775 2.49966 2.51360 2.52593 2.52835 2.53285 2.55597 2.59257 2.59628 2.62795 2.63030 2.68300 2.69995 2.72494 2.74603 2.76860 2.78273 2.82436 2.83499 2.84021 2.86893 2.88729 2.89941 2.92119 2.96154 2.98507 3.01265 3.03130 3.03721 3.06798 3.08042 3.11791 3.17506 3.22902 3.29458 3.33690 3.50084 3.70668 4.03088 4.19325 4.21101 4.35805 4.36299 4.38169 4.42436 4.46720 4.47634 4.49699 4.52438 4.56544 4.64858 4.65690 4.72840 4.75708 4.82897 5.02081 5.10733
12.10652
-16.6278 1.0307 2.1874 16.8027 |XX|YY|ZZ|XY|XZ|YZ| -21.1094 -96.6604 -110.9239 23.9528 19.6936 -0.7385
|XX|YY|ZZ|XY|XZ|YZ| 55.1219 -20.4292 -34.6927 23.9528 19.6936 -0.7385
|XXX|YYY|ZZZ|XYY|XXY|XXZ|XZZ|YZZ|YYZ|XYZ| -221.3926 5.8312 3.8782 -61.5594 -82.7593 18.1245 -36.0546 -21.5183 -11.0585 -50.0094
|XXXX|YYYY|ZZZZ|XXXY|XXXZ|YYYX|YYYZ|ZZZX|ZZZY|XXYY|XXZZ|YYZZ|XXYZ|YYXZ|ZZXY| -4764.7917 -1456.6821 -462.0644 284.7000 532.8302 170.8839 9.6133 114.1736 9.7485 -1152.6304 -1103.8407 -330.4619 -39.2800 32.6769 12.1198
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284.10689 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| 15.3775 20.5282 32.9824 62.9733 68.1055 103.0494 134.1209 176.8468 201.9385 212.5320 231.5481 255.6848 291.1489 303.0681 324.6412 337.1554 344.2871 387.4589 390.7017 421.3024 443.7627 481.5867 504.2907 551.4672 562.8196 580.4203 614.2015 622.8064 655.1272 670.5695 702.3569 745.4735 761.0377 779.9653 855.4313 870.5637 892.7936 905.8275 920.9722 945.9146 963.7303 996.5342 1011.0502 1021.4110 1047.5002 1058.3756 1065.8020 1086.4902 1092.0464 1123.0210 1131.1676 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298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 6 6 6 6 7 1 1 6 6 8 7 6 6 6 6 6 6 16 8 8 7 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 12.00000 12.00000 12.00000 14.00307 1.00783 1.00783 12.00000 12.00000 15.99491 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 31.97207 15.99491 15.99491 14.00307 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
2659.4926 10449.9396 12014.3408 0.99996 0.00848 0.00055 -0.00847 0.99996 -0.00249 -0.00057 0.00249 1.00000 1 0.03257 0.00829 0.00721 0.67860 0.17270 0.15022 22.12 29.54 47.45 90.60 97.99 148.27 192.97 254.44 290.54 305.79 333.15 367.87 418.90 436.05 467.09 485.09 495.35 557.47 562.13 606.16 638.48 692.90 725.56 793.44 809.77 835.10 883.70 896.08 942.58 964.80 1010.53 1072.57 1094.96 1122.20 1230.77 1252.55 1284.53 1303.28 1325.07 1360.96 1386.59 1433.79 1454.68 1469.58 1507.12 1522.77 1533.45 1563.22 1571.21 1615.78 1627.50 1683.94 1721.32 1744.48 1751.57 1776.56 1779.52 1815.06 1829.31 1883.07 1910.27 1932.75 1972.11 1995.09 2028.26 2070.69 2086.34 2108.51 2131.22 2136.03 2204.49 2234.24 2270.34 2287.19 2297.22 2359.03 2363.07 2368.95 2372.30 2384.16 2395.68 2476.58 2542.86 2546.03 2585.95 2601.70 2733.36 4632.94 4687.58 4724.93 4734.32 4741.33 4752.82 4759.68 4826.69 4847.32 4850.88 4886.61 4911.05 4959.31 5217.59 5386.78 5402.76 5566.78 5605.12 0.332528 0.349763 0.350707 0.284508 -1249.757679 -1249.740445 -1249.739501 -1249.805699 2.220292D-04
MUNgauss RevisionA2.1 retrievium 30-Apr-2021 DUDE C[C@]1(CC[NH2+]C1)C(=O)Nc2cccc(c2)S(=O)(=O)N C62888645 RHF 6-31G(d) (6D,10F) C1 284.106888 |X|Y|Z| 73.695049 35.396598 20.145735
37.456540 13 6 7 11 2
|36.858105| |12.440639|36.858105| |7.427700|12.270836|36.858105| |5.014081|7.697482|12.384139|36.858105| |5.085206|7.997746|7.875694|12.596817|53.358707| |4.580094|7.065568|6.519818|9.229326|25.598411|0.500000| |4.225400|5.811075|5.888135|9.000638|25.732592|0.321373|0.500000| |7.513785|12.401805|7.972044|7.850145|17.323098|0.260740|0.251539|36.858105| |7.341023|12.366594|7.628321|6.114949|8.888046|0.199204|0.135791|7.683207|36.858105| |5.187197|8.045163|6.304423|6.269351|9.908810|0.269212|0.150524|7.032746|15.730199|73.516695| |6.606376|7.701810|5.644873|4.446069|6.106760|0.133282|0.101215|5.203196|14.246842|15.096253|53.358707| |4.437685|4.969393|4.130069|3.571027|4.924878|0.111053|0.084986|3.910851|7.786255|12.041875|18.133317|36.858105| |3.838284|3.958795|3.288722|2.893129|4.073940|0.090249|0.072570|3.299279|5.383314|8.587790|10.691589|13.789442|36.858105| |3.002434|3.115802|2.719631|2.476308|3.465644|0.077023|0.063073|2.711955|4.015435|6.865688|7.005452|7.939626|13.720164|36.858105| |2.703735|2.901905|2.634790|2.458390|3.388747|0.076196|0.061907|2.554124|3.742551|6.720067|6.168873|6.868557|7.938699|13.802260|36.858105| |2.899879|3.248565|3.022168|2.842933|3.842860|0.087748|0.069233|2.815935|4.348831|8.071574|7.015378|8.000086|6.922793|7.983859|13.719384|36.858105| |3.617730|4.224671|3.861642|3.525741|4.715243|0.108657|0.082234|3.479015|6.230381|11.310922|10.612069|13.737559|7.928779|6.854550|7.888295|13.809839|36.858105| |2.401676|2.712007|2.655254|2.605208|3.459345|0.078831|0.063662|2.433759|3.408582|6.571496|5.028496|4.752962|4.209811|4.732663|6.936504|10.736769|7.011732|388.023441| |2.508424|2.914638|2.972563|2.976572|3.829536|0.087579|0.070080|2.606121|3.631413|7.152564|5.120805|4.500842|3.724944|3.838129|4.934473|7.387834|6.689954|94.648883|73.516695| |2.155206|2.417300|2.333336|2.336699|3.190011|0.073037|0.059699|2.242665|2.981920|5.852046|4.289368|3.942217|3.708626|4.304925|6.104815|7.320931|5.174818|94.906501|13.580481|73.516695| |2.153117|2.348205|2.327222|2.240531|2.931604|0.065014|0.054503|2.094753|2.827185|5.206816|4.261808|3.893879|3.660773|4.233933|5.922215|7.080887|5.096183|82.497110|13.503578|13.782229|53.358707| |17.572112|8.756302|6.801095|4.477616|5.756492|0.108814|0.099185|5.476290|6.509025|8.250269|9.212394|4.591989|3.970022|3.098899|2.786240|2.988013|3.733060|17.491084|4.561953|3.861583|3.056754|0.500000| |17.567375|8.738615|5.420601|4.141916|6.107357|0.116949|0.106520|6.639109|6.720937|8.745169|8.849765|4.528579|4.136299|3.181556|2.780957|2.900401|3.553825|16.793816|4.283482|3.821190|2.880745|0.300465|0.500000| |17.582941|8.819450|6.751641|4.820414|6.596571|0.116070|0.117188|7.021979|5.417379|7.556101|6.563077|3.548586|3.154675|2.566427|2.344138|2.499867|3.025086|15.167090|3.979274|3.439485|2.630775|0.304241|0.301943|0.500000| |6.216959|8.636660|17.610200|8.744158|7.976302|0.150192|0.128551|5.715895|7.274354|10.690524|8.158538|4.480178|3.464805|2.876540|2.828855|3.318525|4.326020|20.756872|5.923908|4.436609|3.503429|0.180206|0.132279|0.151122|0.500000| |7.302759|8.804706|17.592773|8.805788|8.484917|0.140415|0.144045|6.711886|5.578515|8.357604|6.227144|3.476540|2.895687|2.429559|2.337591|2.620429|3.230548|16.574495|4.579275|3.678918|2.848320|0.190445|0.144551|0.214511|0.303103|0.500000| |4.182445|6.075256|8.644177|17.679088|12.314213|0.242131|0.197635|5.892929|5.773732|11.491252|5.902537|3.658802|2.916372|2.538892|2.584719|3.068215|3.810274|20.542907|6.078989|4.561729|3.324209|0.108250|0.099551|0.108755|0.222284|0.177165|0.500000| |4.326345|5.803051|8.682881|17.657539|12.256681|0.185096|0.233517|6.291022|4.595258|8.262729|4.897263|2.980991|2.495772|2.174700|2.160860|2.458989|2.951375|16.347472|4.641638|3.707936|2.744112|0.108796|0.100547|0.122932|0.185167|0.226768|0.300859|0.500000| |7.117871|8.776059|6.945762|6.749081|12.353157|0.182839|0.226846|17.621636|5.547066|8.966842|5.745396|3.279633|2.860109|2.394024|2.252299|2.446743|2.942649|15.284213|4.077239|3.541143|2.569633|0.144565|0.172474|0.220038|0.139373|0.190618|0.139024|0.172465|0.500000| |6.325076|8.578217|5.656309|5.700616|12.269298|0.234523|0.207575|17.653524|7.119221|12.360492|6.887979|3.955784|3.438052|2.825405|2.627311|2.845034|3.458866|17.293367|4.531966|4.056611|2.828356|0.132010|0.179089|0.159971|0.125684|0.136311|0.132584|0.132677|0.299382|0.500000| |7.757578|7.326731|5.412186|4.059252|5.466204|0.113902|0.092667|4.841413|9.448000|10.869724|26.086988|9.182134|7.066291|4.724412|4.034848|4.355581|5.943552|22.971895|5.799279|4.945723|3.900669|0.248263|0.214652|0.150379|0.159082|0.129390|0.106860|0.094248|0.114793|0.128791|0.500000| |4.107688|3.984209|3.208675|2.783626|3.972742|0.086244|0.071254|3.339402|5.089610|7.806503|9.831671|8.927542|17.711919|8.907385|5.648901|4.977430|5.642049|24.188885|5.501600|5.483805|4.152883|0.117512|0.129317|0.093349|0.091707|0.080085|0.076094|0.067392|0.081584|0.097891|0.203491|0.500000| |2.717174|2.748475|2.405903|2.201903|3.099088|0.068107|0.057174|2.441317|3.384264|5.776250|5.687466|5.652952|8.920357|17.741932|8.937288|5.663770|4.944350|27.774138|5.708762|6.628548|5.003338|0.077695|0.081022|0.065583|0.069847|0.060755|0.062150|0.054475|0.060843|0.071112|0.111165|0.215309|0.500000| |2.347338|2.497439|2.303994|2.180659|3.004021|0.067136|0.055674|2.244496|3.102062|5.626915|4.914192|4.952410|5.642936|8.917211|17.750924|8.894448|5.629435|46.955296|8.026717|11.601529|8.547287|0.067019|0.066999|0.057536|0.068311|0.057532|0.063758|0.054000|0.055708|0.064172|0.091554|0.124120|0.214728|0.500000| |3.652030|4.486009|4.362034|4.072146|5.231059|0.121774|0.090092|3.679620|6.535432|12.594133|9.662835|8.873905|5.638507|4.949104|5.637246|8.960452|17.801804|47.874556|14.086489|8.681417|6.573427|0.104141|0.096129|0.085785|0.140393|0.098633|0.127804|0.092943|0.085868|0.098645|0.151484|0.123959|0.107491|0.124225|0.500000| |1.946473|2.110500|2.088416|2.033533|2.684437|0.059414|0.050434|1.915027|2.500516|4.633468|3.710496|3.315805|3.202294|3.742558|5.067553|5.539283|4.138557|61.233018|10.739507|13.746617|25.886488|0.056000|0.053432|0.048980|0.063316|0.052608|0.061322|0.051318|0.048265|0.053073|0.069866|0.075795|0.093635|0.160045|0.109541|0.500000| |2.149309|2.341516|2.370776|2.272578|2.915866|0.064069|0.054197|2.072389|2.774503|5.056355|4.158399|3.671583|3.370384|3.722998|4.838508|5.881873|4.744692|60.706303|13.282088|10.359865|25.905291|0.062831|0.057991|0.053836|0.073847|0.059467|0.069128|0.057070|0.052156|0.056410|0.078497|0.079326|0.090409|0.135709|0.131259|0.317267|0.500000|
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