Version2.0 2020-07-31T03:54:34Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 13-Jul-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE CCOC(=O)Nc1cc2c(c(n1)N)nc(n2N)SCc3ccc4c(c3)OCO4 C27731881 RHF 6-31G(d) (6D,7F) CCOC(=O)Nc1cc2c(c(n1)N)nc(n2N)SCc3ccc4c(c3)OCO4 C01[X(C17H18N6O4S1)] 132 C1 460 CCOC(=O)Nc1nc(N)c2c(c1)n(N)c(n2)SCc1ccc2c(c1)OCO2 CCOC(=O)Nc1nc(N)c2c(c1)n(N)c(n2)SCc1ccc2c(c1)OCO2 CCOC(=O)Nc1cc2n(N)c(SCc3ccc4OCOc4c3)nc2c(N)n1 InChIKey=VBZBSNAAAJMNDK-UHFFFAOYSA-N InChI=1S/C17H18N6O4S/c1-2-25-17(24)21-13-6-10-14(15(18)20-13)22-16(23(10)19)28-7-9-3-4-11-12(5-9)27-8-26-11/h3-6H,2,7-8,19H2,1H3,(H3,18,20,21,24) InChI=1/C17H18N6O4S/c1-2-25-17(24)21-13-6-10-14(15(18)20-13)22-16(23(10)19)28-7-9-3-4-11-12(5-9)27-8-26-11/h3-6H,2,7-8,19H2,1H3,(H3,18,20,21,24)/f/h21H,18H2 CCOC(=O)Nc1cc2c(c(n1)N)nc(n2N)SCc3ccc4c(c3)OCO4 C01[X(C17H18N6O4S1)] 132 C01 460 CCOC(=O)Nc1nc(N)c2c(c1)n(N)c(n2)SCc1ccc2c(c1)OCO2 CCOC(=O)N[C]1[CH][C]2[C]([C]([N]1)N)N=C(N2N)SC[C]1[CH][CH][C]2[C]([CH]1)OCO2 CCOC(=O)N[C]1[CH][C]2[C](N=C(SC[C]3[CH][CH][C]4OCO[C]4[CH]3)N2N)[C](N)[N]1 InChIKey=VBZBSNAAAJMNDK-UHFFFAOYSA-N InChI=1S/C17H18N6O4S/c1-2-25-17(24)21-13-6-10-14(15(18)20-13)22-16(23(10)19)28-7-9-3-4-11-12(5-9)27-8-26-11/h3-6H,2,7-8,19H2,1H3,(H3,18,20,21,24) InChI=1/C17H18N6O4S/c1-2-25-17(24)21-13-6-10-14(15(18)20-13)22-16(23(10)19)28-7-9-3-4-11-12(5-9)27-8-26-11/h3-6H,2,7-8,19H2,1H3,(H3,18,20,21,24)/f/h21H,18H2 2552.6520789602 -1677.8905503 1-A 23861.9936 105 355 460 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -91.95621 -20.60674 -20.60648 -20.59863 -20.52416 -15.65522 -15.62206 -15.59361 -15.56232 -15.55502 -15.53717 -11.39616 -11.35359 -11.33504 -11.32060 -11.31619 -11.29921 -11.29792 -11.28648 -11.28284 -11.26427 -11.25033 -11.24243 -11.24204 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11.02324
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511.8053 524.7659 560.4261 616.0807 645.5833 660.4298 670.3760 689.9751 733.2740 752.3075 761.3537 766.7464 788.4378 801.2172 830.4240 839.7052 841.5334 854.9782 868.7109 871.8317 885.7522 890.2594 899.2283 927.4056 938.8091 991.0877 994.0265 997.8733 1008.6297 1017.2576 1057.6257 1074.7463 1116.5750 1134.5532 1180.4232 1185.5678 1193.5346 1204.3792 1221.1353 1244.8734 1246.4568 1266.6456 1272.2280 1299.8619 1300.1051 1318.2201 1332.5786 1347.0415 1357.1882 1370.3681 1407.9150 1412.6494 1415.4992 1425.3450 1433.7397 1456.9687 1479.5210 1515.5125 1540.4671 1580.2236 1585.5657 1589.7713 1609.9045 1616.7512 1630.4373 1632.2684 1636.3731 1643.6910 1673.2272 1676.9915 1697.0719 1713.6415 1720.2192 1792.8324 1807.9944 1816.5657 1825.5391 1830.3574 1861.8302 2014.7086 3214.4155 3248.8918 3262.0070 3281.1813 3281.3160 3283.5635 3317.4091 3333.9036 3337.6466 3372.1242 3390.7198 3393.2269 3403.7676 3736.0058 3820.7706 3835.7704 3893.6001 3942.4351 6.4824 4.8898 4.7995 5.8955 5.3500 5.1096 4.1299 2.9421 3.6092 4.3555 5.1358 4.4377 3.7116 6.5676 5.2260 5.6357 5.5280 5.3262 5.5174 3.1647 1.5227 4.9517 4.1580 2.8843 5.1297 1.2902 6.9083 4.0868 3.6902 4.1960 2.2730 3.1290 2.8028 2.8665 1.3184 1.1171 5.9133 6.2483 6.9045 5.6504 5.0349 5.8117 4.7760 7.0049 6.9931 5.4957 5.7759 7.3518 4.1371 5.1455 1.9274 6.0232 3.2235 6.8928 1.5120 4.8699 6.5001 5.1792 1.4704 1.6512 2.2136 1.5136 1.8088 2.9471 1.3455 3.3778 3.5868 7.3605 4.5428 4.2775 3.8751 2.5995 1.7673 1.6574 2.2039 1.4695 3.1652 1.6631 1.6140 1.8431 1.8133 1.1800 5.0672 3.1787 4.9947 1.6816 3.0762 1.0886 1.4176 1.1561 4.4215 6.3655 1.2640 1.6175 1.4555 3.7958 3.0498 5.1810 1.0413 1.1569 4.0531 1.0548 1.1377 3.2118 3.3298 1.1365 4.2668 2.0081 6.0677 7.0521 2.1590 7.1434 1.1319 10.8449 1.0361 1.0636 1.0636 1.1035 1.0594 1.0995 1.1105 1.1091 1.1100 1.0910 1.0935 1.0937 1.0955 1.0466 1.0471 1.1004 1.0780 1.1034 0.0005 0.0009 0.0015 0.0025 0.0033 0.0094 0.0114 0.0116 0.0155 0.0263 0.0359 0.0396 0.0423 0.1067 0.1098 0.1447 0.1495 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34.0662 8.6390 6.1622 95.4249 3.4854 27.7590 50.4745 180.7960 139.9128 19.0830 4.8007 3.3400 0.6753 2.0228 3.9083 40.5023 3.3762 10.4428 8.3519 1.8431 3.2964 30.9144 7.9588 19.8075 9.7672 67.8905 11.6434 30.9710 3.8330 14.8087 10.6901 24.7680 3.7609 42.1577 18.0634 129.7197 25.2468 1.2820 16.2904 5.5144 63.0510 80.5748 144.1523 2.5141 66.8763 22.1903 39.1372 9.4463 18.3282 52.1115 64.2802 55.6234 50.1968 213.8810 2.5810 298.6628 641.4619 82.1467 158.5981 270.0776 1.2417 10.9554 2.9454 216.9420 61.7691 3.3056 10.9323 14.1830 78.4244 81.3047 195.0397 3.9688 31.8394 175.4342 1.9757 99.7115 402.3230 484.8661 0.2796 230.7538 44.4763 438.3995 5.4250 553.9892 1.0937 48.8949 411.9217 26.7081 137.6747 9.3308 21.4855 9.4557 42.7110 54.8185 63.9885 2.2360 10.5176 10.7442 3.4552 7.1573 7.0366 71.0682 11.6477 55.1451 55.6212 0.3377 6.5362 1.7854 1.3527 1.0343 0.8915 1.0057 0.2799 0.5933 0.4306 0.0769 0.4471 0.7411 2.0490 0.5395 1.3117 0.1947 0.7598 1.6054 0.6848 0.1032 0.8355 1.1417 0.7775 2.1170 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MUNgauss RevisionA2.0 retrievium 31-Jul-2020 DUDE CCOC(=O)Nc1cc2c(c(n1)N)nc(n2N)SCc3ccc4c(c3)OCO4 C27731881 RHF 6-31G(d) (6D,10F) C1 402.111025 |X|Y|Z| 149.042542 32.871815 23.827607
48.873276 20 6 7 8 16 14 3 2 1
|36.858105| |12.581878|36.858105| |8.050896|13.390021|73.516695| |5.270853|8.118111|25.411759|36.858105| |4.610501|7.178654|15.211110|16.054331|73.516695| |4.202415|5.419035|15.484864|13.942889|14.773535|53.358707| |3.221596|3.966495|9.537462|7.666052|11.461646|18.505664|36.858105| |2.796184|3.254479|7.492585|5.233191|8.034173|10.878245|13.765402|36.858105| |2.344209|2.690314|5.846354|3.985294|6.588414|7.170672|8.185846|13.672566|36.858105| |2.220559|2.579274|5.450364|3.779297|6.602299|6.334692|7.074400|7.846054|13.829656|36.858105| |2.445844|2.930165|6.196373|4.518764|8.239795|7.308183|8.319233|6.847674|8.003840|13.620155|36.858105| |2.943779|3.664479|8.154265|6.538102|11.621577|11.149449|14.387265|7.925917|7.014475|8.075595|14.448269|53.358707| |2.236424|2.661367|5.378437|3.789847|7.257678|5.613421|5.414593|4.600351|5.235911|7.916640|14.007664|11.290257|53.358707| 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|1.165830|1.257250|2.420763|1.485169|2.647522|2.187443|1.817102|1.969333|2.290572|2.406659|2.113560|2.538638|2.865743|3.948737|3.101097|3.566493|3.466295|29.295681|5.075209|8.050628|6.992959|7.940174|13.784294|36.858105| |1.270087|1.380621|2.677685|1.660238|2.963300|2.464702|2.082504|2.275204|2.716075|2.895541|2.483656|2.924915|3.352057|4.948612|3.919015|4.303234|4.078822|39.136751|7.558767|13.550735|7.888576|6.741043|7.926154|13.968583|36.858105| |1.102762|1.185204|2.266316|1.382958|2.471961|2.019385|1.658155|1.785918|2.039145|2.122303|1.893839|2.307100|2.569385|3.383922|2.637061|3.127946|3.077649|23.654523|3.834633|5.184548|4.687072|5.401989|8.539282|14.034591|7.763433|73.516695| |1.031336|1.101336|2.099318|1.271481|2.265219|1.852085|1.506668|1.616921|1.823621|1.884431|1.697830|2.089205|2.305408|2.956532|2.299547|2.776809|2.761236|20.257348|3.198460|4.212323|4.226671|5.361461|8.603607|8.602077|5.363861|24.055594|36.858105| |1.038332|1.108103|2.117753|1.282632|2.278883|1.875199|1.529393|1.640511|1.858546|1.930352|1.736284|2.127467|2.365801|3.050591|2.367519|2.833896|2.803042|21.054789|3.405591|4.662464|5.196776|7.750897|14.038593|8.537589|5.398882|14.925452|13.528834|73.516695| |17.572303|8.850190|12.897478|4.895114|7.453398|5.594282|3.171260|2.763472|2.323303|2.200965|2.419642|3.950921|3.016019|2.583223|1.834389|2.754415|2.636087|11.229175|1.474528|1.323152|1.260775|1.155407|1.114046|1.155879|1.257393|1.938087|1.022676|1.838176|0.500000| |17.569702|8.847536|12.888274|4.891179|7.447350|5.603815|3.167909|2.830369|2.354180|2.190212|2.365112|3.838933|2.909322|2.575662|1.850596|2.809237|2.724329|11.361269|1.476217|1.327148|1.255333|1.152668|1.119306|1.168855|1.272378|1.969286|1.035986|1.849798|0.300826|0.500000| |17.555299|8.895558|10.221796|4.275184|7.106447|4.714246|2.779959|2.440030|2.093928|2.008628|2.209646|3.546496|2.800766|2.385459|1.689775|2.507899|2.401219|10.443565|1.383474|1.248753|1.184997|1.091469|1.060113|1.104576|1.198319|1.864786|0.982964|1.756788|0.300702|0.300730|0.500000| |8.814900|17.624716|16.536724|7.286128|12.926833|6.716564|3.792475|3.061953|2.592758|2.550880|2.961975|5.024304|3.755741|2.934896|2.021841|2.986658|2.760692|12.129959|1.621469|1.437329|1.354603|1.232645|1.190947|1.245416|1.366841|2.084427|1.090484|1.955614|0.211181|0.172986|0.211679|0.500000| |8.813809|17.619474|16.527451|7.277459|12.903108|6.735381|3.787826|3.153871|2.636126|2.534737|2.864705|4.802233|3.557154|2.924331|2.043773|3.056984|2.862338|12.297466|1.623888|1.442572|1.348022|1.229444|1.197440|1.261707|1.386175|2.123336|1.106655|1.969697|0.172998|0.211134|0.211635|0.302538|0.500000| |4.358537|5.207173|15.129900|9.523063|10.891368|26.089245|9.276895|7.444159|4.868265|4.107750|4.426155|8.173456|4.756302|4.345193|3.116054|5.124713|4.726290|17.496042|2.177089|1.869944|1.742960|1.551194|1.483136|1.558283|1.744793|2.561739|1.328440|2.393246|0.121061|0.122925|0.097718|0.126956|0.129136|0.500000| |2.858776|3.233495|7.482937|4.875480|7.253646|9.850012|8.827234|17.752355|8.737326|5.578662|4.943082|7.694152|4.974500|5.814940|4.543665|8.849517|8.325164|24.013409|2.754568|2.308683|2.108795|1.845555|1.763910|1.875149|2.140545|3.047162|1.561495|2.807105|0.078447|0.082395|0.068799|0.082434|0.087042|0.218402|0.500000| |2.013152|2.355925|4.687920|3.210343|6.112046|4.728260|4.438252|4.050482|4.830611|7.362375|9.435976|8.188670|26.060440|9.517574|4.767374|5.601240|4.317661|25.480382|3.953748|3.064209|2.716511|2.282986|2.150722|2.309814|2.738784|3.652835|1.826797|3.335655|0.055298|0.053844|0.051890|0.067417|0.064855|0.084072|0.091760|0.500000| |2.343188|2.834116|5.617789|3.995327|8.029348|5.593276|5.061791|4.103620|4.354214|5.842593|9.512540|10.591810|26.042557|6.510939|3.689175|4.780919|3.836356|20.221928|2.961461|2.421224|2.201889|1.904771|1.808361|1.922842|2.215781|3.104069|1.575537|2.861481|0.064165|0.061450|0.060239|0.083207|0.077570|0.095395|0.093061|0.312669|0.500000| |2.003853|2.190574|4.582023|2.866278|4.724724|4.755676|4.176662|5.918707|6.850845|4.855356|3.740788|4.862322|4.124878|6.376733|6.204836|13.211624|25.912489|36.606662|3.547729|2.985387|2.637666|2.286869|2.213466|2.406743|2.804931|3.872103|1.950424|3.470382|0.054792|0.057730|0.050365|0.057320|0.060697|0.098566|0.179407|0.082764|0.075242|0.500000| |1.993980|2.155897|4.549454|2.809947|4.552919|4.756075|4.167600|5.900689|6.847425|4.850792|3.736224|4.858214|4.127071|6.368127|6.195968|13.213443|25.914324|36.568022|3.543556|2.978421|2.735104|2.349623|2.208687|2.330287|2.684237|3.692923|1.893962|3.447502|0.055590|0.057020|0.049893|0.056901|0.058436|0.100877|0.177566|0.081915|0.074612|0.322455|0.500000| |1.505193|1.659613|3.288397|2.083802|3.696634|3.177703|2.812747|3.067481|3.935803|4.619923|3.743710|4.098030|5.104943|9.306313|6.643898|6.182185|5.165049|56.474954|17.651778|8.851175|7.185006|4.718436|4.008401|4.238177|5.620333|5.864184|2.864103|5.548294|0.041841|0.041413|0.038993|0.046090|0.045528|0.061633|0.076289|0.119708|0.087828|0.091787|0.095962|0.500000| |1.514768|1.682626|3.314928|2.117825|3.811181|3.193423|2.832463|3.088066|3.964523|4.667460|3.779275|4.127965|5.141380|9.452504|6.711227|6.219929|5.183222|56.514449|17.643352|8.843406|5.695292|4.197876|3.997800|4.739371|7.074773|6.674910|3.062473|5.606266|0.041613|0.041836|0.039356|0.046503|0.046818|0.061335|0.076812|0.123682|0.089542|0.096345|0.092026|0.303151|0.500000| |1.290931|1.394135|2.726458|1.680159|2.955671|2.527193|2.137982|2.323161|2.777183|2.990421|2.576047|3.022364|3.502697|5.100006|3.956511|4.345017|4.057380|37.150514|7.061426|8.957437|17.719227|8.914539|5.722060|5.014147|5.625988|6.591323|3.449209|7.409056|0.036082|0.035660|0.033677|0.038658|0.038147|0.050104|0.060294|0.078241|0.063413|0.073387|0.078653|0.218194|0.145284|0.500000| |1.109604|1.184912|2.284041|1.386347|2.445802|2.049360|1.686179|1.812477|2.079490|2.180266|1.944634|2.357791|2.654881|3.500699|2.711118|3.185538|3.106612|24.359837|4.074024|5.588851|8.795340|17.747153|8.934461|5.640261|4.885411|7.763760|4.651003|12.156033|0.030952|0.030751|0.029187|0.032810|0.032575|0.040929|0.048059|0.058457|0.049517|0.058257|0.060755|0.111931|0.096819|0.213247|0.500000| |1.309664|1.430190|2.772368|1.727329|3.098278|2.557873|2.167843|2.370036|2.833303|3.021617|2.587476|3.043907|3.476194|5.141700|4.057064|4.473263|4.212525|38.751993|6.950176|8.781024|5.609963|4.884634|5.638539|8.950977|17.735678|12.211842|4.663016|7.770801|0.035831|0.036502|0.034326|0.039235|0.040120|0.050067|0.061827|0.079149|0.063967|0.082010|0.075668|0.141637|0.208376|0.123541|0.106400|0.500000| |0.988412|1.054697|2.000091|1.209224|2.162397|1.749836|1.415993|1.506420|1.685322|1.749054|1.595204|1.970844|2.182373|2.716207|2.082330|2.531234|2.503243|17.797961|2.826137|3.576761|3.586486|4.410670|6.308603|6.307520|4.412902|16.596446|17.667320|16.595618|0.027204|0.027541|0.026249|0.029067|0.029479|0.034812|0.040389|0.048017|0.041710|0.049379|0.047877|0.071463|0.076619|0.083809|0.110839|0.111110|0.500000| |1.016960|1.081885|2.063153|1.244385|2.207926|1.815228|1.470173|1.586340|1.778457|1.812962|1.629837|2.020985|2.192366|2.816708|2.218640|2.721069|2.751116|19.566306|2.948069|3.761502|3.772793|4.645828|6.682492|6.681764|4.647806|16.566604|17.588994|16.566008|0.028009|0.028466|0.026916|0.029661|0.030203|0.036338|0.042889|0.047871|0.041686|0.054245|0.052563|0.073370|0.077964|0.087642|0.115556|0.115853|0.297185|0.500000|
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