Version2.0 2020-07-31T04:58:05Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 25-Jul-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE COc1cc(cc(c1OC)OC)[C@H]2[C@@H]3C(=NN=C3OC(=C2C#N)N)C(F)(F)F C01062035 RHF 6-31G(d) (6D,7F) COc1cc(cc(c1OC)OC)[C@H]2[C@@H]3C(=NN=C3OC(=C2C#N)N)C(F)(F)F C01[X(C17H15F3N4O4)] 123 C1 450 N#CC1=C(N)OC2=NN=C([C@H]2[C@@H]1c1cc(OC)c(c(c1)OC)OC)C(F)(F)F N#CC1=C(N)OC2=NN=C([C@H]2[C@@H]1c1cc(OC)c(c(c1)OC)OC)C(F)(F)F COc1cc(cc(OC)c1OC)[C@H]2[C@H]3C(=NN=C3C(F)(F)F)OC(=C2C#N)N InChIKey=LFVOPHIQVFZMGJ-VXGBXAGGSA-N InChI=1S/C17H15F3N4O4/c1-25-9-4-7(5-10(26-2)13(9)27-3)11-8(6-21)15(22)28-16-12(11)14(23-24-16)17(18,19)20/h4-5,11-12H,22H2,1-3H3/t11-,12-/m1/s1 InChI=1/C17H15F3N4O4/c1-25-9-4-7(5-10(26-2)13(9)27-3)11-8(6-21)15(22)28-16-12(11)14(23-24-16)17(18,19)20/h4-5,11-12H,22H2,1-3H3/t11-,12-/m1/s1 COc1cc(cc(c1OC)OC)[C@H]2[C@@H]3C(=NN=C3OC(=C2C#N)N)C(F)(F)F C01[X(C17H15F3N4O4)] 123 C01 450 N#CC1=C(N)OC2=NN=C([C@H]2[C@@H]1c1cc(OC)c(c(c1)OC)OC)C(F)(F)F N#CC1=C(N)OC2=NN=C([C@H]2[C@@H]1[C]1[CH][C]([C]([C]([CH]1)OC)OC)OC)C(F)(F)F CO[C]1[CH][C]([CH][C](OC)[C]1OC)[C@H]2[C@H]3C(=NN=C3C(F)(F)F)OC(=C2C#N)N InChIKey=LFVOPHIQVFZMGJ-VXGBXAGGSA-N InChI=1S/C17H15F3N4O4/c1-25-9-4-7(5-10(26-2)13(9)27-3)11-8(6-21)15(22)28-16-12(11)14(23-24-16)17(18,19)20/h4-5,11-12H,22H2,1-3H3/t11-,12-/m1/s1 InChI=1/C17H15F3N4O4/c1-25-9-4-7(5-10(26-2)13(9)27-3)11-8(6-21)15(22)28-16-12(11)14(23-24-16)17(18,19)20/h4-5,11-12H,22H2,1-3H3/t11-,12-/m1/s1 2801.4978276900 -1467.9405159 1-A 9922.1503 102 348 450 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -26.35690 -26.35656 -26.35453 -20.68341 -20.59535 -20.59378 -20.56521 -15.64044 -15.62301 -15.61910 -15.57430 -11.52883 -11.41233 -11.38326 -11.32304 -11.30863 -11.30705 -11.30318 -11.30222 -11.28770 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28.2589 66.2752 67.2797 53.4858 0.7133 52.8903 45.2757 39.8050 0.0881 45.6951 4.9642 2.0748 281.2867 38.0169 28.0330 25.2546 41.6886 212.7734 66.1444 46.7378 183.2295 328.4425 147.7520 49.9571 81.8906 85.5033 504.5888 174.4451 33.3497 238.8495 33.8908 1.3299 29.5555 4.7677 5.9238 4.8883 2.4536 26.3723 18.3391 198.6767 259.5102 231.3398 25.0670 591.5226 0.9202 225.5894 75.2712 47.6573 45.9974 55.2848 12.7443 2.5675 45.2213 48.0483 43.9953 54.7850 40.3008 43.9447 6.6674 4.6161 129.3877 77.2546 1.5885 1.9793 2.0535 0.0475 0.4535 0.2257 0.7952 1.5762 0.9118 0.8645 0.6150 0.2094 0.1430 0.6138 2.3495 0.9852 2.6207 1.5420 0.3055 0.6531 2.5266 0.3582 0.6017 1.6112 1.0535 2.2770 0.5497 5.5470 1.5347 2.4623 5.0393 2.0899 0.3054 0.5471 2.1148 0.8450 3.5604 4.4109 2.9036 1.4783 3.4164 1.6195 5.9335 0.7104 1.0266 1.0561 2.1932 1.0162 3.4681 5.5330 6.5665 1.5977 3.1997 12.4534 9.0535 0.9108 0.9015 10.2162 3.0668 6.2550 1.9800 0.6229 16.8828 3.0846 2.6266 12.6997 15.0330 1.8731 15.1836 4.1707 1.9214 2.4848 5.7437 4.9488 2.1834 3.0307 1.0336 6.0649 1.1835 2.5080 4.3888 0.6626 1.7267 3.0178 9.0960 10.3917 8.6718 6.9466 2.1527 1.1374 4.1354 7.4619 7.4642 4.1112 22.1995 19.4575 21.4710 18.1676 10.9577 14.9898 10.8356 26.2872 3.9518 77.6085 24.3363 16.3877 41.6488 146.0617 77.2456 88.7345 103.1071 62.8611 13.4371 36.0295 38.5547 33.6304 147.7683 132.8017 143.5555 40.5708 48.1663 122.0417 59.7426 0.7499 0.7500 0.7467 0.7461 0.7489 0.7336 0.7491 0.7228 0.7323 0.7230 0.4885 0.3377 0.7473 0.4217 0.6488 0.5430 0.4279 0.7037 0.7411 0.6247 0.5174 0.2694 0.6959 0.7499 0.7061 0.2324 0.7139 0.1441 0.2521 0.6767 0.2111 0.6274 0.6836 0.3033 0.2441 0.6878 0.6413 0.6006 0.7343 0.2463 0.2407 0.6389 0.2203 0.2770 0.2374 0.3795 0.7035 0.1634 0.4731 0.7493 0.1725 0.1282 0.5906 0.0491 0.2943 0.2896 0.6908 0.1604 0.5920 0.2669 0.6058 0.6974 0.7212 0.6702 0.6891 0.3175 0.7461 0.4807 0.1478 0.7167 0.4628 0.7440 0.7460 0.7114 0.6415 0.3893 0.7498 0.3883 0.7150 0.6098 0.6208 0.2287 0.3590 0.4821 0.3734 0.6541 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0.2432 0.4340 0.0464 0.0421 0.0126 0.3078 0.6354 0.8173 0.8537 0.8562 0.6735 0.8013 0.4859 0.3522 0.3597 0.2947 0.7875
298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 6 8 6 6 6 6 6 6 8 6 8 6 6 1 6 1 6 7 7 6 8 6 6 6 7 7 6 9 9 9 1 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 15.99491 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 15.99491 12.00000 15.99491 12.00000 12.00000 1.00783 12.00000 1.00783 12.00000 14.00307 14.00307 12.00000 15.99491 12.00000 12.00000 12.00000 14.00307 14.00307 12.00000 18.99840 18.99840 18.99840 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
8182.6568 12143.4505 16044.4713 0.99922 0.03927 -0.00425 -0.03906 0.99841 0.04068 0.00584 -0.04048 0.99916 1 0.01059 0.00713 0.00540 0.22056 0.14862 0.11248 24.75 35.55 53.77 73.60 76.97 102.85 113.75 118.84 130.85 149.80 164.13 214.94 231.81 236.63 253.66 272.07 299.47 333.82 338.30 352.09 404.95 414.41 450.92 458.74 469.49 497.18 544.03 566.61 574.13 581.17 625.67 673.34 696.79 713.72 736.69 758.20 813.15 821.86 836.04 857.98 873.44 923.71 936.68 972.18 991.05 1012.02 1054.57 1092.84 1102.75 1134.45 1154.13 1179.05 1213.62 1253.27 1293.99 1361.84 1368.57 1450.87 1491.37 1495.31 1542.22 1608.43 1660.31 1695.16 1714.96 1720.25 1785.46 1797.74 1848.17 1855.36 1857.18 1861.68 1862.14 1878.32 1897.81 1910.33 1920.85 1925.48 1946.96 1954.16 1963.99 2015.70 2019.45 2023.70 2080.63 2139.46 2169.79 2199.46 2226.02 2269.63 2307.93 2334.43 2359.34 2366.72 2372.25 2376.64 2377.61 2379.76 2388.35 2389.37 2454.79 2562.26 2581.08 2584.77 2644.70 2701.11 2714.56 3703.68 4616.31 4620.26 4628.87 4636.32 4661.47 4709.68 4713.61 4724.58 4777.60 4795.02 4795.40 4892.18 4915.78 5493.81 5665.14 0.340471 0.365098 0.366042 0.283824 -1467.600045 -1467.575418 -1467.574473 -1467.656692 2.757639D-04
MUNgauss RevisionA2.0 retrievium 31-Jul-2020 DUDE COc1cc(cc(c1OC)OC)[C@H]2[C@@H]3C(=NN=C3OC(=C2C#N)N)C(F)(F)F C01062035 RHF 6-31G(d) (6D,10F) C1 396.104540 |X|Y|Z| 73.455887 56.708183 36.201652
53.227194 15 6 7 8 12 2 1
|36.858105| |13.601121|73.516695| |8.018674|25.229695|36.858105| |6.747818|14.018182|13.669775|36.858105| |4.532075|9.263480|7.929009|13.790057|36.858105| |3.799063|8.223252|6.856988|7.927996|13.717922|36.858105| |3.986787|9.412984|7.922797|6.863500|7.931952|13.730905|36.858105| |5.268580|14.634963|13.723936|7.903354|6.853486|7.898486|13.663437|36.858105| |4.697864|12.745523|8.013862|5.223462|4.610599|5.225554|8.003180|14.081058|73.516695| |4.170717|10.411330|5.967275|4.292350|3.859904|4.295860|5.960714|8.154648|24.069838|36.858105| |3.218479|7.316746|5.300157|4.628521|5.207639|7.896216|14.188796|8.226142|12.763981|5.857926|73.516695| |2.667053|5.724445|3.989967|3.799723|4.522092|6.739113|8.021280|5.270006|8.376862|4.151484|24.194028|36.858105| |3.691515|6.878361|5.019707|7.595608|12.495602|7.531647|5.008521|4.426098|5.987466|2.966391|6.853658|3.666266|36.858105| |3.981817|6.986765|4.844437|7.497915|8.966124|5.614160|4.209860|4.015600|5.579865|2.784632|5.877474|3.092596|17.554948|0.500000| |3.120295|5.796850|4.037783|5.374169|7.476429|6.009128|4.290470|3.744062|5.285892|2.756729|6.255786|3.463698|12.332407|0.246193|36.858105| |2.945403|5.664175|3.996823|4.993772|7.153697|6.846939|4.779652|3.934622|5.556576|2.925288|7.113669|4.050961|8.810626|0.174770|17.529727|0.500000| |3.117917|5.601918|3.709733|4.739466|5.522171|4.510344|3.597304|3.347713|4.877940|2.637665|5.364123|2.900278|7.135793|0.190565|12.661027|0.248780|36.858105| |2.652042|4.682884|2.997719|3.676615|4.158410|3.561068|2.934690|2.746516|4.131229|2.248880|4.534062|2.505576|5.376255|0.150129|8.279351|0.179733|15.142994|53.358707| |2.409799|4.288484|2.763239|3.383007|3.977550|3.485092|2.819400|2.578618|3.890628|2.083868|4.413701|2.506703|5.479497|0.148038|8.199907|0.178126|8.694628|18.371292|53.358707| |2.584569|4.691426|3.118528|3.921473|4.963870|4.318761|3.310034|2.934561|4.329668|2.274495|5.097579|2.923931|7.624748|0.184639|12.794971|0.250709|8.634630|12.117017|20.687801|36.858105| |2.357455|4.307370|2.850069|3.494533|4.432724|4.060761|3.136419|2.740516|4.093827|2.123097|4.943764|2.921349|6.455669|0.154737|7.731284|0.186518|5.428174|7.545653|11.388772|14.259390|73.516695| |2.516983|4.647074|3.126959|3.876986|5.090271|4.667500|3.504815|3.017625|4.450710|2.247147|5.450453|3.228130|7.483874|0.171023|6.843224|0.170094|4.626514|5.938598|7.587637|8.324997|25.075060|36.858105| |3.031468|5.658305|3.959064|5.224343|7.484858|6.220609|4.351724|3.727873|5.280707|2.593106|6.378082|3.627742|12.459599|0.247016|7.734936|0.185051|4.962295|5.857008|6.716271|7.079770|14.267409|14.122324|36.858105| |3.049101|5.739082|3.967738|4.953196|6.400190|5.735601|4.346971|3.789850|5.452869|2.594796|6.464540|3.653182|7.451465|0.178424|5.014415|0.129418|3.705195|4.465876|4.925020|4.631113|9.318797|8.072225|13.317522|36.858105| |2.928647|5.518097|3.702036|4.331178|5.093582|4.824527|4.004875|3.592879|5.341614|2.509527|6.156554|3.468397|5.292952|0.135580|3.877238|0.102621|3.055588|3.744058|4.060596|3.632628|7.223160|5.659952|7.417479|16.729040|53.358707| |2.195623|4.053037|2.663390|3.148255|3.906516|3.790949|3.023966|2.623458|3.986190|2.017248|4.898054|2.973853|4.983362|0.122043|4.645339|0.123203|3.509966|4.657773|5.818222|5.528396|15.327197|14.113836|7.885920|6.792850|7.449359|53.358707| |3.535410|6.317676|4.077710|4.983325|5.167756|4.278713|3.662545|3.592892|5.281320|2.946437|5.431423|2.823197|5.492289|0.152998|7.096675|0.174724|12.685779|10.784508|7.146808|5.161704|6.822993|3.514445|3.898076|3.163858|3.688922|3.837194|36.858105| |3.031177|5.317464|3.270285|3.763093|3.813906|3.333902|2.975444|2.950126|4.529040|2.588256|4.598145|2.424412|4.050907|0.114705|5.074580|0.130316|8.157459|9.748025|6.391762|4.264075|5.841828|2.953380|3.141821|2.624661|3.128715|3.340506|14.553651|97.533100| |4.441381|7.497983|4.698008|5.943242|5.417676|4.188967|3.675345|3.825957|5.589200|3.067804|5.319597|2.690335|5.512385|0.169574|5.880623|0.139630|8.192689|8.071826|5.984535|4.424637|6.169148|3.330368|3.841745|3.233275|3.817153|3.669296|14.385574|20.137609|97.533100| |3.584225|6.814722|4.531402|5.198384|5.493202|4.929006|4.345988|4.194117|6.105210|3.496404|6.432097|3.278148|5.140238|0.132416|6.381515|0.184191|8.220313|7.695369|5.862000|4.500509|6.286776|3.334807|3.740522|3.110853|3.663757|3.699416|14.415508|20.096411|20.087394|97.533100| |17.562461|16.429229|7.019113|6.755005|4.599377|3.744583|3.786216|4.753664|7.351226|3.863658|5.436522|2.575669|3.875512|0.118650|3.370409|0.087025|3.514452|4.027153|3.558719|2.762707|4.373167|2.572573|3.072109|2.975488|3.797140|3.014368|4.167444|8.004881|12.612321|9.256948|0.500000| |17.566029|16.437906|7.049197|6.745868|4.596233|3.752369|3.802832|4.784279|7.440167|3.590054|5.459561|2.597293|3.858514|0.118973|3.137146|0.080861|3.063960|3.588035|3.326039|2.640404|4.341110|2.651394|3.233680|3.338113|4.420142|3.156010|3.326828|6.401954|9.327191|7.381738|0.298637|0.500000| |17.650947|17.018861|5.892100|4.916088|3.629489|3.190110|3.414695|4.429202|7.629213|3.967182|5.121848|2.409967|3.053188|0.090463|2.660615|0.070566|2.684535|3.179435|2.902559|2.258850|3.697661|2.204647|2.592219|2.626904|3.489287|2.664017|3.039938|6.073021|8.330476|6.963525|0.299944|0.300108|0.500000| |7.536434|12.580603|8.884874|17.785178|8.957707|5.651328|4.952358|5.632619|7.498242|3.631771|6.529427|3.141801|7.089342|0.233549|5.113626|0.124348|4.816874|5.185448|4.704858|3.890471|6.083191|3.727653|4.901123|4.596748|5.506509|4.126876|5.109428|8.789408|15.179568|10.960780|0.227737|0.225250|0.146940|0.500000| |3.140814|6.524705|4.947525|5.649487|8.917940|17.764196|8.905664|5.627937|7.500903|3.630981|12.594076|7.517445|6.995622|0.140999|6.180588|0.213493|4.398854|4.874807|4.967796|4.660106|8.127778|5.319950|6.684826|5.907235|6.617196|5.906261|3.946990|7.099932|8.321400|10.062683|0.086788|0.087022|0.075206|0.124438|0.500000| |3.668113|8.629336|4.676468|3.534520|3.212269|3.536665|4.672393|5.913046|16.902348|17.631469|8.633227|3.661039|2.561939|0.067486|2.389049|0.069967|2.294737|2.714994|2.538006|2.019614|3.389536|2.017286|2.295769|2.327331|3.112387|2.503377|2.532023|5.111147|5.927921|6.590783|0.093367|0.089279|0.100961|0.085826|0.085830|0.500000| |3.570951|8.409995|5.186501|4.033998|3.849902|4.489814|6.263282|7.208289|16.439484|17.573731|11.962050|4.740814|2.989388|0.076407|2.860407|0.086560|2.725879|3.157977|2.926810|2.352267|3.895859|2.298864|2.621407|2.578614|3.355267|2.807086|3.032263|6.004512|6.855305|8.348557|0.095227|0.087334|0.093059|0.094308|0.108072|0.299686|0.500000| |4.794022|11.968603|6.270685|4.484406|3.850566|4.037229|5.182443|7.213025|16.440392|17.575892|8.410919|3.550246|2.991867|0.079551|2.802407|0.081275|2.761555|3.189306|2.901953|2.299211|3.756617|2.211241|2.551905|2.514661|3.278836|2.678035|3.192680|6.337597|7.649321|8.535512|0.125967|0.108940|0.127954|0.108118|0.094255|0.299672|0.298574|0.500000| |2.411003|5.127573|3.419556|3.191792|3.624014|4.912457|5.893771|4.433510|7.659526|3.947293|17.018131|17.650695|3.036020|0.073171|2.909358|0.092680|2.513813|3.012647|3.010242|2.525349|4.503761|2.759397|3.024996|3.078907|4.073771|3.543502|2.475998|4.894636|5.329197|6.416246|0.064445|0.065002|0.061667|0.075252|0.146670|0.100756|0.126265|0.092476|0.500000| |2.612386|5.509225|3.841926|3.785539|4.615539|6.761709|7.116190|4.835747|7.528262|3.600779|16.448924|17.569169|3.841842|0.089367|3.503176|0.111562|2.853751|3.387435|3.467347|3.018755|5.534606|3.570569|4.032998|4.240155|5.570160|4.565880|2.704062|5.212651|5.857027|6.839840|0.069626|0.072255|0.065314|0.087669|0.223346|0.089671|0.108581|0.087485|0.299879|0.500000| |2.560064|5.389459|3.750020|3.710402|4.553702|6.710095|6.955798|4.702665|7.300287|3.810367|16.425548|17.553597|3.828187|0.088219|3.826497|0.130489|3.182969|3.731330|3.731016|3.210656|5.639255|3.408585|3.734954|3.562817|4.454963|4.212380|3.062914|5.911835|6.360447|8.146354|0.070175|0.068913|0.064073|0.086146|0.227975|0.092484|0.123433|0.093735|0.300209|0.298648|0.500000| |2.007205|3.668403|2.369579|2.766801|3.330783|3.221227|2.639755|2.327152|3.588277|1.841339|4.330656|2.624025|4.195881|0.106542|4.143499|0.109504|3.291742|4.538857|5.823603|5.223053|14.590093|9.503335|5.865307|5.084930|5.895986|26.036733|2.644281|5.292382|5.650118|5.675503|0.056593|0.058635|0.050137|0.075109|0.100822|0.046914|0.052356|0.050144|0.064910|0.080668|0.076377|0.500000| |2.198514|4.063300|2.656731|3.100493|3.769847|3.684570|3.001820|2.624230|4.014078|2.006970|4.884287|2.954583|4.569543|0.114355|4.014001|0.106974|3.113469|4.075620|4.871787|4.455720|10.841615|9.429055|7.192540|7.644794|9.055168|26.035907|2.586080|5.076576|5.682652|5.656237|0.060775|0.065153|0.054600|0.082812|0.114965|0.051128|0.056539|0.054072|0.072285|0.094392|0.083200|0.312502|0.500000|
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