Version2.4 2021-05-26T08:30:42Z 10.1021/jm300687e Gaussian16 RevisionB.01 CFLINN 01-Jan-2021 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE COc1cccc(c1)C(=O)C2=C(C(=O)N([C@H]2c3cccc(c3)Br)CCCn4ccnc4)[O-] C09045737 RHF 6-31G(d) (6D,7F) COc1cccc(c1)C(=O)C2=C(C(=O)N([C@H]2c3cccc(c3)Br)CCCn4ccnc4)[O-] C01[X(C24H21Br1N3O4)] 153 C1 537 COc1cccc(c1)C(=O)C1=C([O-])C(=O)N([C@H]1c1cccc(c1)Br)CCCn1cncc1 COc1cccc(c1)C(=O)C1=C([O-])C(=O)N([C@H]1c1cccc(c1)Br)CCCn1cncc1 COc1cccc(c1)C(=O)C2=C([O-])C(=O)N(CCCn3ccnc3)[C@H]2c4cccc(Br)c4 InChIKey=YGDPKXYTBSAIQP-NRFANRHFSA-M InChI=1S/C24H22BrN3O4/c1-32-19-8-3-6-17(14-19)22(29)20-21(16-5-2-7-18(25)13-16)28(24(31)23(20)30)11-4-10-27-12-9-26-15-27/h2-3,5-9,12-15,21,30H,4,10-11H2,1H3/p-1/t21-/m0/s1 InChI=1/C24H22BrN3O4/c1-32-19-8-3-6-17(14-19)22(29)20-21(16-5-2-7-18(25)13-16)28(24(31)23(20)30)11-4-10-27-12-9-26-15-27/h2-3,5-9,12-15,21,30H,4,10-11H2,1H3/p-1/t21-/m0/s1/fC24H21BrN3O4/h30h/q-1 COc1cccc(c1)C(=O)C2=C(C(=O)N([C@H]2c3cccc(c3)Br)CCCn4ccnc4)[O-] C01[X(C24H21Br1N3O4)] 153 C01 537 COc1cccc(c1)C(=O)C1=C([O-])C(=O)N([C@H]1c1cccc(c1)Br)CCCn1cncc1 CO[C]1[CH][CH][CH][C]([CH]1)[C]([C]1[C](=O)C(=O)N([C@H]1[C]1[CH][CH][CH][C]([CH]1)Br)CCC[N]1[CH][N][CH]=C1)=O CO[C]1[CH][CH][CH][C]([CH]1)C(=O)[C]2[C@H]([C]3[CH][CH][CH][C](Br)[CH]3)N(CCCN4[CH][N]C=C4)C(=O)C2=O InChIKey=TVPDYPQTYSJPBE-NRFANRHFSA-N InChI=1S/C24H21BrN3O4/c1-32-19-8-3-6-17(14-19)22(29)20-21(16-5-2-7-18(25)13-16)28(24(31)23(20)30)11-4-10-27-12-9-26-15-27/h2-3,5-9,12-15,21H,4,10-11H2,1H3/t21-/m0/s1 InChI=1/C24H21BrN3O4/c1-32-19-8-3-6-17(14-19)22(29)20-21(16-5-2-7-18(25)13-16)28(24(31)23(20)30)11-4-10-27-12-9-26-15-27/h2-3,5-9,12-15,21H,4,10-11H2,1H3/t21-/m0/s1 3639.5774396723 -3953.7760732 1-A 18167.4741 127 410 537 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9.95412
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11719.8800 25691.4403 30037.0865 0.99987 0.01580 -0.00397 -0.01596 0.99892 -0.04358 0.00328 0.04363 0.99904 1 0.00739 0.00337 0.00288 0.15399 0.07025 0.06008 17.86 20.98 23.05 31.91 38.39 51.70 74.55 83.31 90.05 94.72 101.75 132.73 150.76 172.23 218.02 230.46 252.74 275.68 288.81 335.37 348.74 358.78 380.28 420.21 430.86 447.64 465.99 490.61 501.34 520.05 524.06 557.36 571.87 660.75 696.69 708.14 726.47 782.67 836.41 881.48 888.54 921.78 963.06 978.84 993.19 1047.80 1051.56 1052.48 1093.37 1118.74 1135.63 1146.79 1162.40 1206.27 1215.65 1221.58 1271.44 1283.80 1287.98 1321.26 1339.09 1367.08 1376.14 1385.86 1426.81 1435.44 1437.29 1458.66 1484.71 1505.76 1556.97 1557.92 1568.80 1573.37 1588.41 1608.47 1622.68 1654.58 1671.34 1696.63 1722.36 1727.77 1728.25 1731.02 1748.38 1763.67 1764.88 1775.51 1817.29 1853.88 1863.12 1873.46 1890.38 1890.95 1920.37 1944.62 1967.28 1977.59 1993.76 2037.96 2055.90 2063.11 2065.67 2074.87 2077.29 2138.37 2152.29 2193.56 2197.33 2210.50 2240.13 2268.62 2291.59 2303.90 2306.71 2348.26 2353.86 2357.64 2361.75 2375.04 2381.61 2384.16 2393.89 2437.88 2481.20 2552.34 2554.70 2580.91 2605.11 2617.10 2803.57 2826.90 4558.21 4595.66 4614.34 4632.00 4661.20 4672.76 4675.48 4699.71 4749.96 4758.98 4811.38 4824.36 4853.93 4863.99 4881.72 4888.90 4898.49 4906.82 4939.55 4943.26 4986.72 0.441991 0.469323 0.470267 0.376922 -3953.334083 -3953.306751 -3953.305806 -3953.399152 3.130840D-04
MUNgauss RevisionA2.1 retrievium 26-May-2021 DUDE COc1cccc(c1)C(=O)C2=C(C(=O)N([C@H]2c3cccc(c3)Br)CCCn4ccnc4)[O-] C09045737 RHF 6-31G(d) (6D,10F) C1 494.071542 |X|Y|Z| 109.168481 64.577919 45.605307
68.506571 26 6 7 23 3
|36.858105| |13.685250|73.516695| |8.019637|24.957929|36.858105| |6.753246|13.979374|13.746713|36.858105| |4.525617|9.242927|7.966669|13.698298|36.858105| |3.797957|8.205665|6.869596|7.899041|13.814793|36.858105| |3.983973|9.385510|7.907016|6.821598|7.932775|13.650191|36.858105| |5.267946|14.554760|13.703418|7.918235|6.911225|7.953813|13.790089|36.858105| |3.115642|7.013304|5.017814|4.413024|4.997759|7.465757|12.485814|7.601701|36.858105| |2.974659|6.668916|4.503404|3.865175|4.154222|5.555016|8.199493|6.552473|15.720364|73.516695| |2.664014|5.736140|3.943137|3.673624|4.255038|6.040838|7.512549|5.250987|13.327380|14.368030|36.858105| |2.238595|4.684970|3.076073|2.902446|3.290384|4.300882|4.930482|3.861324|7.556118|11.404901|13.455015|36.858105| |2.035158|4.156504|2.691198|2.608807|2.961727|3.697908|3.941703|3.209958|5.081849|7.652851|8.089161|12.367018|36.858105| |1.803727|3.623609|2.301480|2.247488|2.520629|3.033570|3.168900|2.673543|3.905884|6.225683|5.409259|7.710722|15.860461|73.516695| |2.201666|4.496618|2.949240|2.893658|3.318151|4.138493|4.302853|3.480505|5.126035|7.251431|8.184069|8.156743|14.055309|14.964941|53.358707| |2.642981|5.556413|3.807803|3.698929|4.339801|5.820933|6.264330|4.694172|7.284459|9.065873|12.537826|7.906481|8.081368|9.668827|17.776447|36.858105| |2.709437|5.597957|3.929965|4.052682|5.075056|6.900598|6.323391|4.614434|6.340665|8.079161|8.689952|6.057041|6.271137|8.278215|12.518501|17.504060|0.500000| |2.886473|6.117186|4.077056|3.810991|4.143106|5.042607|5.712507|4.917049|5.841738|7.834761|7.370847|5.345103|5.446902|7.418469|10.553938|12.435493|0.250400|36.858105| |3.144921|6.485682|4.311886|4.208352|4.483687|4.975037|5.147257|4.728408|4.598213|6.447988|5.129137|3.946574|4.059059|5.917904|7.429509|7.504153|0.207241|13.758899|36.858105| |3.201396|6.437069|3.982226|3.784474|3.739754|3.883001|4.099271|4.142005|3.680669|5.486062|3.899329|3.191054|3.263085|4.967292|5.564807|4.982192|0.134241|7.886195|13.706696|36.858105| |2.974074|6.031794|3.559241|3.229521|3.128251|3.304111|3.663147|3.814306|3.477017|5.362519|3.669798|3.110047|3.154936|4.866310|5.167547|4.395935|0.111291|6.799021|7.928850|13.811125|36.858105| |2.758185|5.748053|3.435197|3.047514|3.014108|3.335448|3.868832|3.928767|3.949833|6.107247|4.302080|3.687359|3.704816|5.621460|5.977119|5.008100|0.117346|7.950145|6.953604|8.020839|13.731660|36.858105| |2.720977|5.780390|3.634938|3.249631|3.355158|3.938701|4.694516|4.410006|5.138188|7.515918|6.125308|5.003631|4.991844|7.098809|8.422710|7.494936|0.155887|13.653195|7.969837|6.877017|7.883073|13.844414|36.858105| |2.375992|4.847045|2.764209|2.440524|2.379289|2.591311|2.992812|3.110584|3.155715|5.231548|3.337694|3.091185|3.073434|4.905228|4.560254|3.540452|0.084901|4.582183|4.099306|4.610319|6.695468|9.986617|6.688187|2539.412838| |2.012202|4.003590|2.576781|2.587808|2.939452|3.453535|3.425682|2.899949|3.762401|5.572352|5.117230|5.120879|7.812018|12.102302|17.994875|7.459092|0.191638|6.067542|5.046876|3.956218|3.613614|3.955645|5.005784|104.760269|36.858105| |1.858350|3.669871|2.294294|2.261975|2.475327|2.818063|2.881278|2.556651|3.156944|4.862390|4.055818|4.185433|5.933304|10.337034|10.446670|5.283035|0.130476|5.154689|4.399162|3.793638|3.694854|4.127937|4.913745|114.734057|12.447206|36.858105| |1.690827|3.272167|2.021740|2.025904|2.204086|2.430694|2.423428|2.189812|2.567143|4.028597|3.125321|3.186040|4.173340|7.615902|6.795812|3.901818|0.103680|3.885023|3.648328|3.303900|3.175873|3.337800|3.677501|96.525732|7.563413|12.478174|36.858105| |1.565361|3.009885|1.826032|1.811064|1.931034|2.100317|2.124088|1.964950|2.246627|3.601610|2.656007|2.725785|3.400437|6.296958|5.215768|3.161600|0.083011|3.269095|3.102061|2.963142|2.971037|3.123877|3.277539|95.956808|4.973400|7.640952|13.110210|53.358707| |1.586210|3.040270|1.821085|1.790384|1.876536|2.017645|2.062528|1.946675|2.156127|3.474959|2.495689|2.509602|3.001166|5.392600|4.614644|2.945985|0.076894|3.205775|3.107305|3.113282|3.225546|3.343831|3.327860|105.592976|4.114123|5.896392|7.535022|18.915340|36.858105| |1.436688|2.736233|1.622983|1.592572|1.658405|1.772204|1.814997|1.727231|1.901887|3.116080|2.165746|2.206790|2.586242|4.736735|3.823336|2.470973|0.064746|2.643697|2.558525|2.584599|2.707179|2.812994|2.774801|93.580233|3.275439|4.372549|5.305501|11.937662|14.090003|36.858105| |1.349112|2.568110|1.530191|1.509217|1.584713|1.700872|1.731476|1.632453|1.830146|3.013601|2.093688|2.175728|2.581526|4.871394|3.724399|2.359010|0.062138|2.436831|2.330065|2.296861|2.365386|2.480524|2.518164|82.128068|3.214202|4.220530|5.291208|11.774744|8.530063|13.921660|53.358707| |1.413622|2.703646|1.629264|1.615900|1.717750|1.860563|1.881315|1.747978|2.000055|3.260531|2.331366|2.440801|2.994359|5.734906|4.360113|2.670976|0.070486|2.700865|2.556090|2.454789|2.479707|2.615381|2.732498|83.596874|3.942034|5.401092|7.601584|19.252801|8.780838|9.031573|20.056064|36.858105| |2.075787|4.310235|2.768903|2.598358|2.889889|3.651399|4.173150|3.425496|6.172604|11.041684|7.883548|15.785139|7.974934|11.699380|7.493815|5.284518|0.123126|4.057870|3.186052|2.692317|2.671782|3.136653|3.998488|94.937980|3.989764|3.465019|2.754480|3.304164|2.247174|2.021012|2.739594|2.230817|73.516695| |17.538354|16.452244|7.038785|6.758848|4.592290|3.746853|3.789371|4.772568|2.974624|5.105955|2.534208|2.149774|1.949424|3.087649|2.843882|2.487115|0.071647|2.632917|2.834242|2.814620|2.599686|2.445797|2.457553|72.303794|1.913025|1.754182|1.604245|2.016609|1.490268|1.355028|1.744292|1.345606|3.574030|0.500000| |17.537103|16.451810|7.030962|6.758148|4.585899|3.744793|3.787796|4.760663|2.963680|4.910863|2.608958|2.189758|2.028573|3.199981|3.032949|2.671553|0.077020|2.966424|3.358624|3.492859|3.157307|2.830697|2.756230|81.461669|2.067005|1.910437|1.752146|2.204676|1.647226|1.485532|1.890306|1.455394|3.572136|0.299274|0.500000| |17.623843|17.026480|5.873952|4.913510|3.623005|3.186214|3.408629|4.416034|2.797219|4.844076|2.419656|2.071488|1.889433|3.002508|2.757600|2.387970|0.066997|2.623259|2.819784|2.935433|2.818187|2.626476|2.543033|79.567328|1.860286|1.743717|1.592490|2.028250|1.519819|1.386158|1.768639|1.352387|3.450435|0.299992|0.300033|0.500000| |7.480717|12.472816|8.855925|17.749914|8.922111|5.642163|4.927966|5.622945|3.534421|5.665583|3.055592|2.501424|2.295027|3.577749|3.448874|3.121220|0.094804|3.245853|3.651134|3.425102|2.940270|2.721794|2.826623|75.843341|2.324695|2.061098|1.880239|2.307512|1.683827|1.507001|1.943178|1.520435|4.033079|0.225126|0.225379|0.146168|0.500000| |3.919209|7.450787|5.663849|8.935718|17.691242|8.938414|5.638970|4.969967|4.070865|6.178150|3.670794|2.963811|2.748377|4.236980|4.182755|3.839533|0.127658|3.611604|3.966846|3.359769|2.803593|2.675544|2.945023|73.002426|2.811827|2.361392|2.146259|2.553159|1.812681|1.606774|2.100660|1.676025|4.672951|0.113438|0.113145|0.089109|0.216679|0.500000| |3.138012|6.511067|4.951215|5.627519|8.924811|17.727461|8.893394|5.655957|6.918499|9.225048|6.374971|4.685251|4.095847|5.949186|6.199929|6.215758|0.221762|4.821271|4.610529|3.546298|3.036241|3.104041|3.728872|83.048503|3.783780|2.973290|2.563285|2.965827|2.056827|1.804291|2.381638|1.934525|6.976969|0.086851|0.086724|0.075095|0.124185|0.215120|0.500000| |4.874785|13.454865|8.948216|5.651876|4.974831|5.648409|8.927876|17.749790|7.074438|12.214034|4.959774|3.804513|3.122295|4.662857|4.499815|4.290043|0.111522|4.622448|4.272120|3.915652|3.839024|4.106571|4.520615|115.334253|2.746903|2.487474|2.120395|2.626907|1.927523|1.721438|2.208822|1.725151|6.149625|0.120200|0.119599|0.121175|0.123986|0.107867|0.124179|0.500000| |3.164357|6.371437|4.363423|4.599192|5.192157|5.580747|5.168091|4.572130|4.389298|6.143299|4.818264|3.726867|3.848432|5.675184|6.987285|6.985910|0.231314|8.944066|17.711963|8.920441|5.650073|4.993437|5.658731|113.276429|4.923407|4.060061|3.508354|3.989154|2.874854|2.389720|3.007664|2.441085|5.390932|0.080743|0.095179|0.077392|0.111278|0.131369|0.146419|0.109815|0.500000| |3.261253|6.277040|3.800920|3.747662|3.631606|3.577413|3.624650|3.725344|3.179413|4.835437|3.293384|2.751383|2.815369|4.378169|4.688043|4.071476|0.114957|5.625808|8.897695|17.705395|8.952060|5.679327|4.953221|130.345492|3.436925|3.297996|3.013731|3.722455|2.887431|2.430674|2.943661|2.293080|4.208056|0.079564|0.102296|0.082972|0.097753|0.092981|0.090811|0.096614|0.215357|0.500000| |2.863342|5.641974|3.199984|2.912703|2.766328|2.849105|3.119106|3.321292|2.954917|4.692215|3.056947|2.664330|2.697982|4.263169|4.282589|3.523392|0.091089|4.916055|5.630872|8.889243|17.749457|8.897749|5.629422|220.470217|3.056849|3.188802|2.848085|3.741681|3.055224|2.623113|3.089442|2.332106|4.170734|0.069228|0.084973|0.077038|0.075508|0.069808|0.072914|0.094034|0.124004|0.214308|0.500000| |2.497306|5.300188|3.305317|2.944140|3.061094|3.652144|4.425691|4.090192|5.332450|8.109370|6.612363|5.890033|5.687397|8.021001|8.664479|6.972788|0.140713|8.899264|5.662494|4.957501|5.625544|8.934782|17.758596|219.502239|4.857361|4.858635|3.556239|4.368945|3.206385|2.729234|3.429310|2.735043|8.403631|0.063470|0.069077|0.065432|0.071339|0.075081|0.098016|0.120009|0.124347|0.107587|0.124054|0.500000| |2.131185|4.210004|2.731014|2.798333|3.207476|3.694348|3.541119|3.009147|3.673079|5.368996|4.760954|4.390511|5.800151|8.885051|12.616195|7.347824|0.215227|6.464023|5.987690|4.512943|3.878449|4.017494|4.913745|102.558091|17.551777|8.835713|6.913667|6.308137|3.989957|3.146784|4.114840|3.632005|6.181609|0.056161|0.061619|0.054297|0.070063|0.086126|0.111915|0.077660|0.171813|0.110215|0.090425|0.123990|0.500000| |1.858696|3.661102|2.348792|2.388532|2.736141|3.189167|3.094280|2.615590|3.403699|5.161241|4.497650|4.753252|7.281965|12.912978|12.566357|5.835809|0.160422|4.624008|4.027490|3.267465|3.000707|3.234693|3.943609|89.784925|17.542322|8.864427|6.976208|6.330085|3.713867|3.067427|4.256771|3.900797|6.867988|0.049629|0.052855|0.047804|0.060121|0.074071|0.099442|0.068698|0.113326|0.081378|0.072398|0.109134|0.302085|0.500000| |1.754389|3.472370|2.155763|2.104643|2.291082|2.623160|2.724330|2.423988|3.075364|4.845826|3.956025|4.366787|6.409278|12.417893|9.538175|4.743393|0.114528|4.469794|3.720757|3.270494|3.286441|3.783193|4.512327|111.799789|8.885775|17.594186|8.864927|9.422028|5.352134|4.281789|5.878605|5.519663|6.604962|0.046167|0.049616|0.046004|0.053272|0.060533|0.076967|0.066417|0.095302|0.079432|0.080105|0.132797|0.173968|0.212949|0.500000| |1.973114|3.918324|2.431837|2.362202|2.539446|2.872737|3.001402|2.716310|3.253298|4.994209|4.106338|4.057489|5.297658|8.686135|9.483728|5.415225|0.129541|6.012684|5.073126|4.505871|4.547982|5.222919|6.121201|139.489535|8.856941|17.566759|8.848278|9.458997|6.361537|4.537461|5.555501|4.863702|5.960493|0.051165|0.056519|0.051581|0.059676|0.066432|0.082038|0.074108|0.122540|0.105308|0.106758|0.161256|0.212400|0.173920|0.302496|0.500000| |1.754339|3.370793|2.086816|2.116288|2.304870|2.503694|2.455071|2.227735|2.529796|3.937852|3.027958|2.976520|3.750963|6.577274|6.321322|3.868610|0.106622|3.957732|3.935233|3.584269|3.328185|3.351154|3.615774|94.235410|6.935506|8.812396|17.548568|12.542513|6.833324|4.806244|6.209790|5.935775|4.554537|0.046177|0.050997|0.045710|0.054867|0.062846|0.073062|0.059295|0.107493|0.092604|0.082993|0.093678|0.208542|0.173718|0.173431|0.210136|0.500000| |1.594244|3.072688|1.902533|1.921676|2.108842|2.327047|2.292910|2.056200|2.440807|3.861716|2.962171|3.089375|4.082567|7.808392|6.318557|3.591675|0.097360|3.404329|3.191766|2.862899|2.731688|2.867797|3.185939|84.479058|6.891295|8.837972|17.582462|12.641581|5.683920|4.549414|6.737855|7.358181|4.821039|0.042365|0.045719|0.041681|0.049677|0.057597|0.069163|0.055124|0.087449|0.073520|0.068625|0.087195|0.170170|0.209127|0.213072|0.173527|0.303349|0.500000| |1.714703|3.292434|1.969505|1.929429|2.008986|2.151231|2.208028|2.099764|2.280873|3.645673|2.627549|2.577506|3.033845|5.280274|4.800661|3.158628|0.082247|3.595080|3.561481|3.674367|3.851572|3.906122|3.760464|119.903654|4.215637|5.862274|6.740561|12.116830|17.819781|8.598928|7.895332|5.972837|4.056513|0.044420|0.049748|0.045594|0.050357|0.053617|0.060290|0.057718|0.089733|0.094120|0.101373|0.097438|0.117616|0.101753|0.139971|0.195322|0.188189|0.138385|0.500000| |1.393975|2.642775|1.552592|1.517440|1.564917|1.659751|1.706726|1.643204|1.778275|2.935745|1.994356|2.019895|2.312623|4.199621|3.392161|2.244927|0.058900|2.428611|2.372246|2.445754|2.600555|2.678678|2.579969|91.978568|2.821905|3.606426|4.135724|8.053483|8.731210|17.795116|12.154641|6.091999|3.316723|0.036458|0.040040|0.037578|0.040072|0.042073|0.046587|0.045729|0.061392|0.064465|0.071493|0.070395|0.076141|0.073353|0.098556|0.106229|0.108047|0.100816|0.193870|0.500000| |1.363166|2.605525|1.576269|1.570845|1.681885|1.827626|1.836278|1.693029|1.962952|3.211458|2.293402|2.437898|3.016937|5.944813|4.289766|2.596122|0.069033|2.548464|2.397042|2.265897|2.262815|2.392304|2.542248|76.183898|3.876317|5.010787|6.819981|12.259539|5.966232|6.040303|12.329160|17.778738|3.995220|0.036247|0.038863|0.036161|0.041048|0.045800|0.053285|0.046276|0.064425|0.058942|0.058877|0.071379|0.097682|0.111866|0.147362|0.119440|0.148007|0.216916|0.127018|0.128020|0.500000|
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