Version2.0
2020-08-01T02:10:57Z
10.1021/jm300687e
Gaussian16
RevisionB.01
SBUNGAY
11-Jul-2020
#N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2)
DUDE Cc1ccc(cc1)c2nc(no2)NC(=O)[C@H](C)Oc3cc(ccc3C(C)C)C C21800585
RHF
6-31G(d)
(6D,7F)
Cc1ccc(cc1)c2nc(no2)NC(=O)[C@H](C)Oc3cc(ccc3C(C)C)C
C01[X(C22H25N3O3)]
153
C1
470
Cc1ccc(cc1)c1onc(n1)NC(=O)[C@@H](Oc1cc(C)ccc1C(C)C)C
Cc1ccc(cc1)c1onc(n1)NC(=O)[C@@H](Oc1cc(C)ccc1C(C)C)C
CC(C)c1ccc(C)cc1O[C@@H](C)C(=O)Nc2noc(n2)c3ccc(C)cc3
InChIKey=SDGUPVQNRDVJCB-INIZCTEOSA-N
InChI=1S/C22H25N3O3/c1-13(2)18-11-8-15(4)12-19(18)27-16(5)20(26)23-22-24-21(28-25-22)17-9-6-14(3)7-10-17/h6-13,16H,1-5H3,(H,23,25,26)/t16-/m0/s1
InChI=1/C22H25N3O3/c1-13(2)18-11-8-15(4)12-19(18)27-16(5)20(26)23-22-24-21(28-25-22)17-9-6-14(3)7-10-17/h6-13,16H,1-5H3,(H,23,25,26)/t16-/m0/s1/f/h23H
Cc1ccc(cc1)c2nc(no2)NC(=O)[C@H](C)Oc3cc(ccc3C(C)C)C
C01[X(C22H25N3O3)]
153
C01
470
Cc1ccc(cc1)c1onc(n1)NC(=O)[C@@H](Oc1cc(C)ccc1C(C)C)C
C[C]1[CH][CH][C]([CH][CH]1)[C]1[N][C]([N]O1)NC(=O)[C@@H](O[C]1[CH][C]([CH][CH][C]1C(C)C)C)C
C[C]1[CH][CH][C]([CH][CH]1)[C]2[N][C]([N]O2)NC(=O)[C@H](C)O[C]3[CH][C](C)[CH][CH][C]3C(C)C
InChIKey=SDGUPVQNRDVJCB-INIZCTEOSA-N
InChI=1S/C22H25N3O3/c1-13(2)18-11-8-15(4)12-19(18)27-16(5)20(26)23-22-24-21(28-25-22)17-9-6-14(3)7-10-17/h6-13,16H,1-5H3,(H,23,25,26)/t16-/m0/s1
InChI=1/C22H25N3O3/c1-13(2)18-11-8-15(4)12-19(18)27-16(5)20(26)23-22-24-21(28-25-22)17-9-6-14(3)7-10-17/h6-13,16H,1-5H3,(H,23,25,26)/t16-/m0/s1/f/h23H
2471.1657214978
-1235.5877726
1-A
17400.2445
101
369
470
|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|
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|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|
0.08069 0.12894 0.14671 0.15353 0.16111 0.20381 0.22111 0.23189 0.24356 0.25055 0.25725 0.26307 0.26751 0.27429 0.27741 0.28399 0.29718 0.30364 0.30912 0.31302 0.31602 0.31700 0.31952 0.32301 0.32471 0.32976 0.33073 0.34710 0.35287 0.36532 0.36699 0.37146 0.37925 0.38717 0.38865 0.39163 0.39562 0.40028 0.40624 0.41122 0.42437 0.43119 0.45558 0.46037 0.46592 0.47566 0.48098 0.48761 0.49250 0.50805 0.52166 0.53471 0.54317 0.54678 0.55861 0.56936 0.59417 0.60270 0.65004 0.66697 0.67479 0.68649 0.69686 0.71400 0.71700 0.72128 0.72298 0.72915 0.73052 0.73297 0.73837 0.74060 0.74691 0.75674 0.76626 0.76826 0.77241 0.77474 0.79662 0.80041 0.80287 0.80671 0.81062 0.81118 0.81315 0.82095 0.82428 0.83375 0.84391 0.84930 0.86828 0.86909 0.88216 0.88490 0.88859 0.89988 0.90975 0.91523 0.92178 0.93365 0.93490 0.94540 0.94664 0.94963 0.95702 0.96701 0.97588 0.97948 0.98575 0.98997 0.99798 1.00533 1.00999 1.01731 1.02389 1.03265 1.03963 1.04894 1.05884 1.06678 1.08015 1.08709 1.09339 1.10110 1.10791 1.11052 1.11809 1.11844 1.12162 1.12658 1.13161 1.13672 1.14196 1.14702 1.14857 1.15207 1.15803 1.16526 1.17347 1.17608 1.18304 1.18881 1.19673 1.20066 1.20492 1.20797 1.22048 1.22990 1.23403 1.24242 1.24526 1.25284 1.25707 1.26504 1.26757 1.27176 1.27600 1.28324 1.28716 1.29812 1.30753 1.31907 1.33955 1.35556 1.35912 1.36606 1.39683 1.40380 1.41207 1.42503 1.43569 1.44116 1.45461 1.47658 1.48402 1.49038 1.49387 1.49822 1.50388 1.52215 1.53507 1.54250 1.56327 1.58129 1.58727 1.60643 1.62402 1.63625 1.63852 1.64593 1.66368 1.67472 1.67870 1.68924 1.69384 1.70892 1.71465 1.71677 1.73539 1.74413 1.74664 1.75354 1.76202 1.77562 1.77627 1.78289 1.80078 1.81481 1.82163 1.83491 1.85593 1.87323 1.89281 1.92448 1.94369 1.94680 1.96511 1.99322 2.04780 2.06558 2.07167 2.07865 2.08360 2.09447 2.10564 2.11104 2.11932 2.12299 2.13291 2.14233 2.16132 2.16783 2.18102 2.18551 2.19036 2.19915 2.20139 2.20841 2.22967 2.23384 2.23687 2.24447 2.25138 2.26541 2.27806 2.27913 2.29991 2.31248 2.31793 2.33146 2.35016 2.35965 2.36358 2.36544 2.37791 2.39395 2.40594 2.42146 2.43118 2.43779 2.43970 2.45487 2.46221 2.46606 2.47637 2.48309 2.48678 2.52255 2.52867 2.54753 2.54901 2.55989 2.57231 2.58043 2.58531 2.59238 2.60556 2.60895 2.62370 2.63188 2.63248 2.63418 2.64757 2.65252 2.66333 2.66665 2.66831 2.69482 2.70387 2.70497 2.71898 2.73142 2.74075 2.74929 2.77114 2.78145 2.78488 2.80835 2.81515 2.86748 2.88919 2.89459 2.91027 2.91635 2.93356 2.96570 2.96944 2.97825 2.98604 3.00204 3.02863 3.04015 3.04212 3.07203 3.07770 3.08941 3.10847 3.11620 3.13333 3.15009 3.17072 3.17713 3.19005 3.21894 3.23375 3.24209 3.25836 3.27169 3.27427 3.31348 3.36582 3.38222 3.42587 3.47129 3.48371 3.54327 3.61509 3.62321 3.77082 3.84525 3.84749 4.29114 4.48702 4.51659 4.53031 4.53100 4.54300 4.54773 4.56964 4.58678 4.63351 4.64832 4.66059 4.69468 4.71327 4.73379 4.74137 4.74326 4.77253 4.79850 4.84459 4.89701 4.90940 4.93875 5.05173 5.08567 5.13841 5.16826 5.25754
10.48528
4.6492 4.2932 2.5105
6.8080
|XX|YY|ZZ|XY|XZ|YZ|
-137.6124 -166.3513 -155.8330 -0.0749 -2.6178 -0.0185
|XX|YY|ZZ|XY|XZ|YZ|
15.6532 -13.0858 -2.5674 -0.0749 -2.6178 -0.0185
|XXX|YYY|ZZZ|XYY|XXY|XXZ|XZZ|YZZ|YYZ|XYZ|
359.5366 19.3151 25.7705 -8.8005 34.8648 -54.8866 -17.5953 -3.3442 9.2257 23.2777
|XXXX|YYYY|ZZZZ|XXXY|XXXZ|YYYX|YYYZ|ZZZX|ZZZY|XXYY|XXZZ|YYZZ|XXYZ|YYXZ|ZZXY|
-17578.9220 -2638.4548 -1729.9639 270.6263 -197.3579 -35.6352 -16.7074 -54.3181 -12.4285 -3590.7829 -3466.1635 -716.9026 87.2622 7.7149 -30.7938
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379.18959
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153
|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|
6.2218 12.2412 13.4500 25.1651 30.6061 34.7978 53.0213 54.2562 69.7126 80.1734 90.9739 93.1759 110.0917 146.0921 189.7936 193.2583 198.5250 225.7989 233.1595 255.1508 257.4873 271.3197 282.5873 294.5431 315.5881 340.6467 345.2639 359.4764 391.1371 405.6111 414.2179 436.5027 443.1087 454.4951 455.7847 518.7080 543.6161 554.8846 561.3090 569.7527 617.2213 638.9510 664.8405 682.1580 699.0536 745.7844 768.6267 788.2169 804.9714 805.9588 824.8877 847.4099 860.3159 872.7152 876.4382 930.7047 940.8915 957.2937 960.2279 974.7074 994.8470 1016.6115 1017.7378 1043.7382 1044.7766 1068.0348 1084.5934 1090.6707 1095.3269 1102.4956 1105.9457 1114.1706 1121.4994 1154.8041 1168.3209 1169.4670 1172.7405 1173.2987 1203.8294 1206.4743 1222.3737 1227.4297 1248.7435 1251.2270 1283.0525 1293.2111 1308.5483 1314.1675 1320.2997 1323.3295 1329.9687 1334.2227 1397.6269 1426.8717 1438.5365 1464.2238 1485.3891 1487.0658 1515.8706 1523.8814 1553.0142 1557.7310 1565.3700 1566.2484 1568.8245 1570.2483 1577.4809 1578.0931 1629.2357 1631.6717 1632.9237 1633.9590 1637.5320 1639.4950 1641.0250 1643.4397 1649.3369 1652.3449 1674.6527 1686.5694 1715.0920 1756.6154 1770.9930 1776.6213 1821.5917 1822.4660 1855.7965 2028.9314 3194.1757 3200.6579 3203.2962 3206.9962 3219.9792 3226.4655 3249.5093 3253.0581 3255.8342 3262.8858 3264.3930 3277.6935 3288.8013 3292.2565 3293.2193 3314.3503 3316.7507 3351.8107 3362.7137 3363.5844 3369.6258 3378.8516 3402.8812 3404.1060 3883.5710
5.2440 1.0952 3.1760 4.3349 1.0403 5.2310 2.9302 4.8932 6.4880 5.9412 3.2868 5.1156 3.4911 5.5912 4.3368 3.0144 5.0879 5.0426 2.4001 1.1741 1.0959 1.6325 1.7056 4.4811 3.0351 4.4608 4.0369 4.5011 4.2588 4.7686 5.0983 4.3443 5.8064 2.9347 2.8257 3.9761 6.9585 2.8212 2.8823 1.2369 3.1196 4.1563 5.2048 4.5762 6.9594 3.5127 4.3815 3.7821 4.8164 4.0894 5.7788 4.4333 5.0086 5.3617 5.0627 1.3367 1.6749 1.2507 2.4818 2.0344 1.8192 1.6283 2.0337 1.5441 5.8483 2.6399 9.9253 1.3627 1.5143 1.3507 1.8471 1.3588 2.7915 2.7472 4.4115 1.6106 1.6263 1.5607 2.1885 1.8101 2.3639 2.1826 4.8608 3.1203 2.7326 2.0084 1.2899 1.9201 2.4099 2.1784 3.4372 1.6701 4.0443 1.6362 3.6009 1.4673 1.4660 1.3145 1.4475 3.3398 1.2654 1.3124 1.4137 1.2718 1.3962 1.3913 1.7829 2.5421 1.0474 1.0554 1.0477 1.0522 1.1058 1.0511 1.1073 1.0729 1.0536 1.0709 2.5546 2.6360 2.6411 5.6781 6.0997 7.3200 5.5393 5.8853 6.1721 10.8720 1.0362 1.0397 1.0386 1.0387 1.0530 1.0676 1.1030 1.1007 1.0987 1.1008 1.1028 1.1036 1.1030 1.1006 1.1021 1.1050 1.0870 1.0894 1.0911 1.0911 1.0909 1.0942 1.0946 1.0948 1.0786
0.0001 0.0001 0.0003 0.0016 0.0006 0.0037 0.0049 0.0085 0.0186 0.0225 0.0160 0.0262 0.0249 0.0703 0.0920 0.0663 0.1181 0.1515 0.0769 0.0450 0.0428 0.0708 0.0802 0.2291 0.1781 0.3050 0.2835 0.3427 0.3839 0.4622 0.5154 0.4877 0.6717 0.3572 0.3459 0.6303 1.2116 0.5118 0.5350 0.2366 0.7002 0.9998 1.3555 1.2547 2.0038 1.1511 1.5251 1.3844 1.8388 1.5651 2.3167 1.8757 2.1842 2.4060 2.2913 0.6822 0.8736 0.6753 1.3482 1.1388 1.0608 0.9915 1.2411 0.9911 3.7612 1.7742 6.8790 0.9550 1.0704 0.9673 1.3311 0.9938 2.0686 2.1585 3.5478 1.2978 1.3178 1.2659 1.8686 1.5523 2.0811 1.9373 4.4658 2.8782 2.6505 1.9790 1.3013 1.9538 2.4751 2.2476 3.5821 1.7516 4.6546 1.9628 4.3904 1.8535 1.9057 1.7127 1.9597 4.5695 1.7982 1.8762 2.0409 1.8382 2.0247 2.0212 2.6139 3.7301 1.6380 1.6556 1.6459 1.6551 1.7470 1.6647 1.7569 1.7074 1.6887 1.7227 4.2211 4.4178 4.5773 10.3230 11.2717 13.6128 10.8295 11.5170 12.5240 26.3690 6.2291 6.2751 6.2791 6.2941 6.4328 6.5481 6.8624 6.8630 6.8621 6.9047 6.9240 6.9852 7.0288 7.0285 7.0426 7.1515 7.0455 7.2113 7.2691 7.2733 7.2982 7.3602 7.4678 7.4749 9.5845
0.8817 0.1257 0.3294 0.0683 0.1907 0.0499 0.4239 2.1718 3.1132 0.4050 0.9217 0.6496 0.1846 0.9334 1.2844 0.8593 0.6388 3.9235 0.7749 0.1321 0.4510 2.0975 2.9994 0.4445 0.9713 3.1290 3.5231 5.8706 5.8116 7.9498 2.1672 0.1221 4.3794 0.0458 1.6292 1.4635 1.5119 1.1369 23.9336 91.1207 5.5608 1.9631 1.1825 4.2920 0.3236 0.6346 0.2658 29.1386 4.9804 4.9951 0.4799 4.0357 6.4072 30.7349 79.9080 30.1309 12.2710 0.0233 0.5565 1.9557 8.8236 6.0756 3.8221 1.7510 51.9555 5.7254 11.7599 1.4443 1.0343 0.6475 10.6702 0.0296 5.8518 46.3450 5.7739 5.2088 22.6311 6.8443 17.3887 0.1509 9.5870 3.8523 138.3254 23.8010 130.4864 139.8551 23.3398 0.5885 19.0149 22.6181 7.8799 0.7168 151.0953 37.0190 14.6487 10.6007 16.5147 0.7348 30.3929 163.8877 2.3659 3.4051 1.4585 11.2129 24.3165 5.8261 52.6749 58.2615 6.2293 7.7049 1.4684 7.3851 20.3567 3.8021 19.3283 1.9102 1.4727 1.0392 387.6883 60.1903 1013.7188 45.1472 25.7839 17.7604 63.2507 22.4248 186.6321 214.1686 35.9126 47.0960 43.9411 34.1873 21.5215 30.2542 0.4697 80.5563 33.1169 25.2487 47.0716 24.8881 21.6824 27.5216 36.9713 14.7992 22.7884 16.2336 17.2724 25.4883 17.8126 22.6564 4.9775 1.0924 54.7464
3.4043 0.6336 3.9444 6.3026 0.4754 2.3932 0.7725 0.6658 0.2482 0.3248 1.3946 0.8286 0.9185 0.3114 3.4893 0.2408 0.4982 1.7102 0.9997 0.3690 0.2667 0.6428 0.5730 0.8681 1.3119 2.3918 1.1491 0.5749 4.1873 0.3468 0.5568 1.3191 2.7276 0.0256 2.1157 6.3359 0.2564 0.0607 0.6545 0.3022 0.7459 2.4795 3.3858 2.5717 8.0195 1.1784 0.2942 3.6047 8.4042 14.5478 1.7544 8.1519 4.9765 16.1426 6.1426 1.3496 0.1909 2.6818 9.3359 4.3491 4.0931 3.7071 5.9872 8.8858 3.9427 6.6510 39.0147 0.7667 4.4354 4.1363 4.3076 0.2509 4.7517 3.9548 5.4915 2.3335 6.0464 0.0486 3.0947 2.9751 3.6372 7.3238 9.9061 4.6629 20.7067 2.7973 13.7521 0.5258 3.0763 1.1039 7.1080 3.7792 17.2380 0.5502 17.6699 1.1164 9.3317 6.3194 6.5869 47.9271 2.0864 1.6132 14.5362 10.4068 4.5089 6.7778 6.0374 28.7076 17.4601 22.1758 20.8114 17.3914 27.9738 5.2755 12.8075 15.6889 38.7897 2.0812 42.0238 2.5491 115.4649 106.0353 8.4408 102.4523 514.3508 45.0406 14.0355 17.1798 34.1538 134.8579 199.1707 214.0122 54.4915 99.9157 7.5709 158.0671 89.2797 107.9287 80.8839 69.2343 70.1273 72.2397 83.2761 57.6519 42.1131 73.5097 86.4755 52.1642 89.1077 121.3553 35.4443 105.0723 31.7145
0.7437 0.7431 0.7487 0.7492 0.7469 0.7477 0.7292 0.7301 0.7377 0.7134 0.7476 0.7498 0.6180 0.6403 0.6698 0.6330 0.2561 0.3718 0.7495 0.5333 0.7200 0.3196 0.3723 0.6843 0.3212 0.5481 0.4998 0.7255 0.2621 0.3885 0.4851 0.6406 0.6965 0.6362 0.0190 0.4293 0.6143 0.6210 0.7072 0.7399 0.7403 0.5992 0.4870 0.7500 0.7490 0.3037 0.7211 0.6662 0.1739 0.1099 0.2610 0.0657 0.1943 0.0922 0.2326 0.7119 0.6575 0.7500 0.4952 0.3374 0.6086 0.1527 0.0615 0.7026 0.3025 0.7043 0.1742 0.7425 0.6836 0.7393 0.7326 0.7498 0.1784 0.6806 0.4056 0.6217 0.1316 0.5002 0.6513 0.7259 0.1389 0.7248 0.3539 0.6733 0.1066 0.6264 0.1704 0.7456 0.5384 0.6653 0.1758 0.4157 0.0978 0.7362 0.6695 0.6454 0.7366 0.7474 0.7362 0.3310 0.7372 0.4962 0.5016 0.5030 0.5992 0.5870 0.3953 0.3772 0.7440 0.7449 0.7429 0.7499 0.5914 0.7411 0.7479 0.7155 0.7038 0.5813 0.3201 0.4720 0.3788 0.2856 0.5113 0.2491 0.3885 0.7453 0.5730 0.2248 0.0227 0.0502 0.0222 0.0546 0.1495 0.0243 0.7488 0.6861 0.7016 0.7401 0.7264 0.7337 0.7500 0.7196 0.7117 0.6817 0.0984 0.5005 0.3951 0.2433 0.3756 0.1806 0.2683 0.1768 0.1307
0.8530 0.8526 0.8563 0.8566 0.8551 0.8557 0.8434 0.8440 0.8491 0.8328 0.8555 0.8570 0.7639 0.7807 0.8022 0.7753 0.4077 0.5421 0.8568 0.6956 0.8372 0.4844 0.5426 0.8125 0.4862 0.7081 0.6664 0.8409 0.4154 0.5596 0.6532 0.7809 0.8211 0.7776 0.0372 0.6008 0.7611 0.7662 0.8285 0.8505 0.8508 0.7494 0.6550 0.8571 0.8565 0.4659 0.8379 0.7997 0.2963 0.1980 0.4140 0.1233 0.3254 0.1689 0.3774 0.8317 0.7934 0.8571 0.6624 0.5046 0.7567 0.2650 0.1158 0.8253 0.4644 0.8265 0.2968 0.8522 0.8121 0.8501 0.8457 0.8570 0.3028 0.8100 0.5771 0.7667 0.2326 0.6668 0.7889 0.8412 0.2439 0.8404 0.5227 0.8047 0.1927 0.7703 0.2912 0.8542 0.7000 0.7990 0.2990 0.5873 0.1782 0.8480 0.8020 0.7845 0.8484 0.8554 0.8480 0.4974 0.8487 0.6633 0.6681 0.6694 0.7494 0.7398 0.5667 0.5477 0.8532 0.8538 0.8525 0.8571 0.7432 0.8513 0.8558 0.8341 0.8262 0.7352 0.4850 0.6413 0.5495 0.4443 0.6766 0.3989 0.5596 0.8541 0.7285 0.3671 0.0443 0.0955 0.0434 0.1036 0.2601 0.0475 0.8564 0.8138 0.8247 0.8506 0.8415 0.8464 0.8571 0.8370 0.8315 0.8107 0.1792 0.6672 0.5664 0.3914 0.5461 0.3060 0.4230 0.3004 0.2312
298.150
1.00000
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
6 6 6 6 6 6 6 6 7 6 7 8 7 6 8 6 1 6 8 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 14.00307 12.00000 14.00307 15.99491 14.00307 12.00000 15.99491 12.00000 1.00783 12.00000 15.99491 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
5290.6140 27586.7189 28777.6304
0.99998 0.00581 0.00229 -0.00588 0.99957 0.02877 -0.00212 -0.02878 0.99958
1
0.01637 0.00314 0.00301
0.34112 0.06542 0.06271
8.95 17.61 19.35 36.21 44.04 50.07 76.29 78.06 100.30 115.35 130.89 134.06 158.40 210.19 273.07 278.06 285.63 324.87 335.46 367.11 370.47 390.37 406.58 423.78 454.06 490.11 496.76 517.21 562.76 583.58 595.97 628.03 637.53 653.92 655.77 746.31 782.14 798.36 807.60 819.75 888.04 919.31 956.56 981.47 1005.78 1073.02 1105.88 1134.07 1158.17 1159.60 1186.83 1219.23 1237.80 1255.64 1261.00 1339.08 1353.73 1377.33 1381.55 1402.39 1431.36 1462.68 1464.30 1501.71 1503.20 1536.66 1560.49 1569.23 1575.93 1586.25 1591.21 1603.04 1613.59 1661.51 1680.95 1682.60 1687.31 1688.12 1732.04 1735.85 1758.72 1766.00 1796.66 1800.24 1846.03 1860.64 1882.71 1890.79 1899.62 1903.98 1913.53 1919.65 2010.87 2052.95 2069.73 2106.69 2137.14 2139.56 2181.00 2192.53 2234.44 2241.23 2252.22 2253.48 2257.19 2259.24 2269.64 2270.52 2344.11 2347.61 2349.41 2350.90 2356.04 2358.87 2361.07 2364.54 2373.03 2377.36 2409.45 2426.60 2467.63 2527.38 2548.06 2556.16 2620.86 2622.12 2670.08 2919.18 4595.71 4605.03 4608.83 4614.15 4632.83 4642.16 4675.32 4680.43 4684.42 4694.56 4696.73 4715.87 4731.85 4736.82 4738.21 4768.61 4772.06 4822.51 4838.19 4839.45 4848.14 4861.41 4895.99 4897.75 5587.59
0.468422
0.494552
0.495496
0.404940
-1235.119351
-1235.093221
-1235.092277
-1235.182833
3.037263D-04
MUNgauss
RevisionA2.0
retrievium
01-Aug-2020
DUDE Cc1ccc(cc1)c2nc(no2)NC(=O)[C@H](C)Oc3cc(ccc3C(C)C)C C21800585
RHF
6-31G(d)
(6D,10F)
C1
379.189592
|X|Y|Z|
44.511508 36.326634 118.740489
57.689765
21
|36.858105|
|12.617509|36.858105|
|7.543233|13.716054|36.858105|
|5.011387|7.894553|13.765387|36.858105|
|4.428614|6.823397|7.937295|13.723670|36.858105|
|5.021814|7.894932|6.885195|7.927571|13.683004|36.858105|
|7.560332|13.664484|7.964291|6.884677|7.939007|13.817451|36.858105|
|3.303802|4.475591|5.084282|7.680422|13.006920|7.713384|5.099079|36.858105|
|2.876804|3.707544|3.915527|5.156205|7.713584|6.469089|4.407863|14.816556|53.358707|
|2.446439|3.032959|3.287630|4.245271|5.439190|4.493651|3.401184|9.265824|19.007512|36.858105|
|2.435487|3.013545|3.420358|4.546283|5.332800|4.103137|3.222373|8.740277|11.584194|14.858165|53.358707|
|2.923666|3.784844|4.537148|6.766612|7.962131|5.220786|3.975961|14.591019|12.000414|9.171602|18.651326|73.516695|
|2.125250|2.548775|2.683311|3.270369|4.012248|3.613158|2.864224|5.676927|11.061431|13.853170|10.909908|9.864299|53.358707|
|1.860669|2.180472|2.308426|2.750851|3.192464|2.884703|2.386865|4.212271|7.085595|7.721496|8.697747|7.892050|18.834260|36.858105|
|1.802604|2.102944|2.266848|2.709028|3.039155|2.680223|2.251210|3.964071|6.150159|6.632772|9.077902|7.976098|11.465128|16.054457|73.516695|
|1.677426|1.928365|1.998914|2.309721|2.654922|2.501655|2.119974|3.292705|5.468249|5.057547|5.794855|5.908032|10.660347|12.424914|14.138306|36.858105|
|1.719891|1.977049|2.019802|2.317796|2.706737|2.613016|2.206484|3.318179|5.673381|4.937596|5.400916|5.720168|10.398521|8.852950|10.507768|17.552562|0.500000|
|1.599722|1.823966|1.885785|2.156034|2.447368|2.321392|1.993896|2.963767|4.784938|4.240332|5.047848|5.323585|7.921713|7.640375|10.816731|12.502577|0.246615|36.858105|
|1.526457|1.732613|1.800144|2.054458|2.304852|2.171907|1.878092|2.781292|4.411200|3.958698|4.860630|5.086748|7.279225|7.876334|12.105045|13.658338|0.259032|8.112797|73.516695|
|1.519450|1.720189|1.785325|2.029758|2.268013|2.142471|1.861067|2.710157|4.251548|3.735502|4.635213|4.944034|6.532176|6.331046|10.255266|7.989154|0.200679|5.219666|24.655212|36.858105|
|1.535036|1.731903|1.771985|1.995134|2.250983|2.174508|1.894315|2.644857|4.199580|3.510530|4.227907|4.671033|6.041032|5.127741|7.883451|6.390511|0.197149|4.425475|14.192964|13.711273|36.858105|
|1.496351|1.675318|1.710011|1.906208|2.126025|2.063830|1.821234|2.444450|3.783308|3.069630|3.789795|4.314190|4.938910|3.967212|6.435240|4.428915|0.133251|3.356768|9.248884|7.879677|13.759080|36.858105|
|1.445147|1.612306|1.663582|1.853697|2.030422|1.941923|1.726833|2.324544|3.497974|2.869648|3.683995|4.201948|4.450852|3.642412|6.280165|3.832621|0.108071|2.996874|8.206461|6.917101|8.020786|13.711048|36.858105|
|1.430443|1.600779|1.672096|1.878234|2.039722|1.916613|1.699554|2.364468|3.522825|2.983686|3.935640|4.388321|4.631846|4.003494|7.286779|4.112195|0.108783|3.214460|9.337804|8.051793|6.960423|7.918505|13.794530|36.858105|
|1.463929|1.649583|1.729865|1.962977|2.148268|2.002882|1.757617|2.542438|3.845577|3.377210|4.429403|4.763753|5.482916|5.176230|9.590340|5.484666|0.135028|4.094267|14.224733|13.702008|7.854488|6.719503|7.833291|13.671351|36.858105|
|1.414961|1.590690|1.686525|1.916359|2.062141|1.896250|1.673525|2.436649|3.595929|3.199297|4.395538|4.696462|5.020454|4.852467|10.092405|4.844875|0.112803|3.986497|11.806057|7.465511|4.970516|4.371668|4.977627|7.489563|12.506478|36.858105|
|1.270125|1.410059|1.485578|1.661566|1.769308|1.647315|1.475958|2.039500|2.977694|2.557412|3.504923|3.883344|3.935159|3.595351|7.108212|3.786270|0.091655|3.371400|8.968115|5.430503|4.079104|3.750309|4.289761|5.974139|7.566512|12.403132|36.858105|
|1.463527|1.648593|1.772878|2.025469|2.142770|1.935333|1.712452|2.528844|3.619498|3.227941|4.672251|5.021628|4.762148|4.360420|9.624326|3.920127|0.094113|3.304399|8.297590|5.170198|3.930937|3.694281|4.336613|6.191834|7.499345|12.419374|7.520494|36.858105|
|1.485534|1.649333|1.658734|1.822799|2.036415|2.022408|1.804805|2.284177|3.522772|2.735178|3.349871|3.939243|4.274849|3.237878|5.207218|3.571580|0.111548|2.860481|6.901204|5.005089|7.553140|12.608511|7.540716|5.017995|4.383463|3.246156|2.912573|2.876180|36.858105|
|17.538052|8.863894|6.033304|4.362558|3.980149|4.547764|6.537948|3.061080|3.693444|2.321530|3.129206|4.832880|2.773976|1.792170|3.082885|1.625252|0.046492|1.538649|2.647105|1.494921|1.520905|1.495885|1.446305|1.422230|1.443382|1.386914|1.247597|1.434825|1.496646|0.500000|
|17.561331|8.847909|5.754623|4.245720|3.966826|4.659303|6.912960|3.052798|3.714782|2.322235|3.107267|4.777956|2.784551|1.793700|3.071008|1.634340|0.046702|1.572781|2.637059|1.468367|1.486885|1.443717|1.386639|1.370183|1.406678|1.359116|1.225398|1.394486|1.438453|0.302206|0.500000|
|17.586601|8.837621|7.211625|4.738835|3.960802|4.175812|5.582934|3.046867|3.584268|2.293838|3.167628|4.960694|2.715255|1.768530|3.078706|1.591763|0.044972|1.524940|2.590865|1.449086|1.453649|1.418095|1.379600|1.374028|1.406319|1.370458|1.234402|1.425914|1.400352|0.301807|0.301486|0.500000|
|6.985979|8.914510|17.716672|8.953225|5.652727|4.958301|5.652959|4.135881|4.473989|2.881523|4.165084|7.004250|3.260448|2.108142|3.729530|1.836341|0.051176|1.742233|2.974537|1.661862|1.641341|1.591521|1.562070|1.577322|1.626029|1.598993|1.418571|1.692635|1.541397|0.158062|0.147325|0.220283|0.500000|
|4.088542|5.630286|8.922636|17.743005|8.913564|5.640960|4.960065|7.072815|6.516286|4.268905|6.707190|13.574107|4.442016|2.808971|5.048796|2.323223|0.063709|2.169725|3.704590|2.057024|1.991924|1.901801|1.872194|1.922384|2.015893|1.996547|1.724885|2.144409|1.795733|0.101293|0.098077|0.112753|0.216130|0.500000|
|4.093389|5.624096|4.960444|5.647652|8.919949|17.744145|8.922607|7.145958|9.844519|4.764997|5.535698|8.543979|5.396553|3.084383|4.953456|2.713635|0.080411|2.503471|4.126667|2.283661|2.349785|2.212226|2.045545|1.999375|2.097003|1.958850|1.698474|1.968191|2.184585|0.106570|0.110058|0.096076|0.107650|0.124196|0.500000|
|7.021916|8.899149|5.655008|4.957225|5.649767|8.963789|17.706575|4.147110|5.214141|3.018592|3.831139|5.903565|3.584838|2.216261|3.688811|2.010927|0.058686|1.900660|3.178866|1.773993|1.824206|1.759869|1.658001|1.618434|1.667061|1.578830|1.403289|1.601236|1.766322|0.181040|0.201791|0.141147|0.124147|0.107630|0.215690|0.500000|
|2.134638|2.548247|2.615094|3.121104|3.898891|3.702451|2.929867|5.233871|10.709677|9.567182|8.117592|8.396815|26.063098|9.272520|10.824541|7.527294|0.243850|5.702014|9.020013|4.606826|4.573406|3.712956|3.218819|3.228792|3.732706|3.316360|2.680279|3.082154|3.319653|0.057101|0.057570|0.055110|0.064423|0.084253|0.117670|0.076142|0.500000|
|1.697370|1.946302|2.003561|2.296741|2.639560|2.518491|2.146089|3.205730|5.257246|4.558702|5.278999|5.645559|8.380694|6.947500|9.689704|8.799407|0.212446|17.559831|10.259055|4.226223|3.799423|2.994735|2.673944|2.812556|3.435500|3.342172|2.857669|2.910708|2.638276|0.045053|0.046591|0.044789|0.051077|0.063678|0.076083|0.056823|0.173585|0.500000|
|1.492596|1.683063|1.724064|1.942037|2.188270|2.110194|1.838738|2.581003|4.112381|3.486482|4.195877|4.582306|6.198388|5.544308|8.268436|8.891702|0.214116|17.591311|13.111350|4.941901|4.371315|3.319956|2.923517|3.082418|3.848047|3.682802|3.274284|3.000196|2.873515|0.040052|0.040944|0.039520|0.044425|0.053992|0.063351|0.049199|0.129641|0.300043|0.500000|
|1.547327|1.758875|1.838181|2.103371|2.344596|2.190278|1.895956|2.830328|4.419041|3.975878|5.004915|5.240693|6.960380|7.000371|11.528353|8.879674|0.174134|17.598601|13.037360|4.835910|3.915584|3.074239|2.852256|3.157600|4.077229|4.284104|3.639767|3.554037|2.598388|0.041245|0.042144|0.041281|0.047569|0.059602|0.064485|0.049923|0.131006|0.300014|0.300424|0.500000|
|1.555763|1.754852|1.777146|1.992971|2.273540|2.231952|1.940390|2.658555|4.302550|3.513047|4.112207|4.593075|6.172913|5.000401|7.322661|6.724699|0.240080|4.761654|13.020143|8.938356|17.711952|8.937390|5.679020|4.997764|5.622614|4.069840|3.463764|3.312432|7.003606|0.042754|0.042126|0.040725|0.045493|0.054702|0.067987|0.052297|0.137583|0.115364|0.134991|0.111255|0.500000|
|1.402446|1.553008|1.598343|1.764126|1.914180|1.839964|1.654414|2.153424|3.189856|2.562403|3.326521|3.881991|3.856622|3.065250|5.338275|3.162229|0.089666|2.565318|6.509080|4.973623|5.674981|8.902086|17.698862|8.948104|5.608932|4.077255|3.694105|3.773110|6.977398|0.039213|0.037322|0.037244|0.041882|0.049436|0.053533|0.044272|0.077822|0.064731|0.069832|0.068268|0.124400|0.500000|
|1.378563|1.534399|1.611011|1.800901|1.926920|1.801646|1.612141|2.208617|3.220987|2.706615|3.665115|4.146814|4.064352|3.455161|6.499594|3.441483|0.090311|2.810992|7.518692|5.694756|4.997738|5.654726|8.996904|17.720182|8.932778|6.977307|6.090004|6.651128|4.103099|0.038125|0.036586|0.036982|0.042541|0.051568|0.051656|0.042576|0.078081|0.069281|0.074839|0.078259|0.108293|0.218089|0.500000|
|1.449737|1.637053|1.738133|1.986914|2.150418|1.969934|1.727532|2.572083|3.830450|3.482917|4.771005|4.980235|5.605850|5.790019|12.619365|5.812664|0.126261|4.887304|14.302895|7.335772|4.782503|3.968599|4.194722|5.618299|9.021757|17.656965|8.938503|8.992379|3.031047|0.039234|0.038799|0.038988|0.045636|0.057545|0.056671|0.045179|0.101019|0.110092|0.121326|0.153728|0.113967|0.096512|0.141254|0.500000|
|1.232471|1.361800|1.432140|1.591992|1.686671|1.576398|1.421305|1.923480|2.788139|2.356800|3.234223|3.646075|3.565990|3.146806|6.114907|3.271398|0.081905|2.892865|7.460063|4.787200|3.849101|3.761783|4.545119|6.399032|6.782837|8.727159|17.532174|6.768479|2.949108|0.033783|0.032974|0.033297|0.038099|0.045849|0.045042|0.037620|0.068146|0.069646|0.078623|0.084713|0.090079|0.112291|0.201864|0.173635|0.500000|
|1.236724|1.369468|1.449110|1.617948|1.707237|1.582447|1.424061|1.958681|2.825477|2.422375|3.377108|3.763888|3.659585|3.309161|6.687576|3.400514|0.081948|3.163190|7.607845|4.321259|3.370197|3.106563|3.473679|4.550461|5.501291|8.781191|17.534335|6.900899|2.504438|0.033645|0.033158|0.033538|0.038633|0.046929|0.045035|0.037543|0.068818|0.075514|0.084857|0.097520|0.082203|0.085655|0.131910|0.214501|0.301522|0.500000|
|1.236633|1.369503|1.432142|1.594779|1.708446|1.606678|1.441229|1.961942|2.894044|2.462014|3.307602|3.682893|3.853557|3.512391|6.666059|3.928839|0.095718|3.573956|9.651985|5.631924|4.278972|3.826942|4.176411|5.426549|6.925196|8.750949|17.552716|5.471339|2.990788|0.033739|0.033296|0.033300|0.037891|0.045641|0.046330|0.038270|0.074221|0.082725|0.099800|0.106186|0.102670|0.099172|0.143761|0.213395|0.301514|0.301162|0.500000|
|1.416440|1.589035|1.716909|1.954640|2.042523|1.838273|1.637414|2.389858|3.370512|2.984838|4.409257|4.795161|4.320052|3.902929|8.733710|3.514304|0.084028|3.122721|7.216932|4.198766|3.291206|3.076446|3.496621|4.639784|5.484516|8.817701|6.884621|17.541385|2.482321|0.038425|0.037540|0.038553|0.045851|0.057919|0.051573|0.042488|0.077700|0.077143|0.078871|0.095912|0.079700|0.086814|0.138449|0.217362|0.167707|0.207521|0.141003|0.500000|
|1.414458|1.582383|1.696509|1.918997|2.015187|1.833113|1.637180|2.335834|3.313878|2.871767|4.129442|4.586782|4.164815|3.635307|7.572787|3.347278|0.083364|2.841235|7.011856|4.566292|3.693596|3.675937|4.563382|6.605073|6.667671|8.705189|6.793784|17.535594|2.892474|0.038752|0.037365|0.038325|0.045192|0.056279|0.051648|0.042671|0.076547|0.070520|0.073160|0.083099|0.085975|0.114443|0.228881|0.173923|0.199690|0.169917|0.138779|0.302293|0.500000|
|1.595135|1.816742|1.970520|2.286302|2.430134|2.160475|1.889430|2.929076|4.179513|3.835705|5.699397|5.942335|5.553242|5.071434|11.782781|4.195790|0.100726|3.438228|8.367692|5.178414|4.011726|3.740351|4.270680|5.745504|6.871337|8.777196|5.476353|17.587723|2.932952|0.043356|0.042003|0.043093|0.051996|0.067713|0.060835|0.048660|0.096909|0.085553|0.084532|0.101450|0.094646|0.103060|0.161644|0.214649|0.138879|0.140960|0.122566|0.301799|0.300546|0.500000|
|1.471991|1.631239|1.627924|1.782488|2.003875|2.013549|1.797997|2.239857|3.492323|2.682457|3.238924|3.818735|4.250463|3.189311|5.025953|3.650705|0.117963|2.974843|6.894273|4.719153|7.169742|8.830089|5.599502|4.189706|3.929235|3.002251|2.725945|2.626572|17.569407|0.041099|0.039855|0.038434|0.041908|0.048479|0.061031|0.049229|0.094009|0.076621|0.084734|0.073696|0.218273|0.141393|0.096612|0.079957|0.075356|0.065807|0.079285|0.064018|0.072137|0.074295|0.500000|
|1.586742|1.767095|1.770436|1.944735|2.184054|2.181616|1.943376|2.436114|3.753938|2.859250|3.484403|4.153744|4.369402|3.191379|5.125411|3.371617|0.105722|2.704015|6.243068|4.390664|6.126824|8.841658|6.387066|4.489998|3.937050|3.003595|2.652281|2.760578|17.528067|0.044650|0.042512|0.041356|0.045506|0.052899|0.065640|0.052861|0.094758|0.070650|0.074114|0.068338|0.161798|0.173839|0.105285|0.078419|0.074515|0.064356|0.074209|0.066379|0.077330|0.079932|0.301921|0.500000|
|1.386796|1.525330|1.534074|1.671066|1.842422|1.829892|1.654126|2.039043|3.086749|2.385789|2.979461|3.542174|3.651338|2.783040|4.586885|3.039176|0.092219|2.517759|5.953733|4.217063|5.704925|8.838987|6.981774|4.677894|3.928521|3.004947|2.794067|2.690396|17.563590|0.038926|0.037317|0.036463|0.039878|0.045869|0.054389|0.045090|0.077705|0.064611|0.070804|0.064617|0.145702|0.205712|0.111186|0.076922|0.080416|0.066968|0.079781|0.065080|0.076665|0.074881|0.301753|0.302275|0.500000|
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