Version2.4 2021-04-30T08:09:25Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 27-Oct-2018 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE c1ccc(cc1)[C@H]2C[C@@H]2Nc3nc4ccccc4o3 C44416909 RHF 6-31G(d) (6D,7F) c1ccc(cc1)[C@H]2C[C@@H]2Nc3nc4ccccc4o3 C01[X(C16H14N2O1)] 93 C1 313 c1ccc(cc1)[C@H]1C[C@@H]1Nc1nc2c(o1)cccc2 c1ccc(cc1)[C@H]1C[C@@H]1Nc1nc2c(o1)cccc2 C1[C@H](Nc2oc3ccccc3n2)[C@H]1c4ccccc4 InChIKey=KTYZYSQZAIABOO-OCCSQVGLSA-N InChI=1S/C16H14N2O/c1-2-6-11(7-3-1)12-10-14(12)18-16-17-13-8-4-5-9-15(13)19-16/h1-9,12,14H,10H2,(H,17,18)/t12-,14+/m1/s1 InChI=1/C16H14N2O/c1-2-6-11(7-3-1)12-10-14(12)18-16-17-13-8-4-5-9-15(13)19-16/h1-9,12,14H,10H2,(H,17,18)/t12-,14+/m1/s1/f/h18H c1ccc(cc1)[C@H]2C[C@@H]2Nc3nc4ccccc4o3 C01[X(C16H14N2O1)] 93 C01 313 c1ccc(cc1)[C@H]1C[C@@H]1Nc1nc2c(o1)cccc2 [CH]1[CH][CH][C]([CH][CH]1)[C@H]1C[C@@H]1NC1=N[C]2[C]([CH][CH][CH][CH]2)O1 [CH]1[CH][CH][C]([CH][CH]1)[C@H]2C[C@@H]2NC3=N[C]4[CH][CH][CH][CH][C]4O3 InChIKey=KTYZYSQZAIABOO-OCCSQVGLSA-N InChI=1S/C16H14N2O/c1-2-6-11(7-3-1)12-10-14(12)18-16-17-13-8-4-5-9-15(13)19-16/h1-9,12,14H,10H2,(H,17,18)/t12-,14+/m1/s1 InChI=1/C16H14N2O/c1-2-6-11(7-3-1)12-10-14(12)18-16-17-13-8-4-5-9-15(13)19-16/h1-9,12,14H,10H2,(H,17,18)/t12-,14+/m1/s1/f/h18H 1261.4725396149 -797.7875067 1-A 8069.4659 66 247 313 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -20.63806 -15.59595 -15.53950 -11.37471 -11.28633 -11.28005 -11.25693 -11.24853 -11.24782 -11.23841 -11.23640 -11.23584 -11.23495 -11.23322 -11.23205 -11.23097 -11.22948 -11.22842 -11.22729 -1.50056 -1.28027 -1.23263 -1.17291 -1.14756 -1.12838 -1.02436 -1.01914 -1.01788 -0.99854 -0.87473 -0.87332 -0.84914 -0.83134 -0.82605 -0.79806 -0.78861 -0.72890 -0.71889 -0.70900 -0.68704 -0.67833 -0.67290 -0.65212 -0.63329 -0.61518 -0.61261 -0.60409 -0.58921 -0.58584 -0.57000 -0.54400 -0.52356 -0.52075 -0.51062 -0.50760 -0.49947 -0.49239 -0.49134 -0.45083 -0.44272 -0.43975 -0.40322 -0.33798 -0.32784 -0.32007 -0.28962 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| 0.13702 0.13989 0.14341 0.16466 0.22786 0.23256 0.23979 0.24461 0.25307 0.26743 0.29408 0.29651 0.30680 0.30857 0.32138 0.32674 0.33225 0.33396 0.35149 0.35843 0.36922 0.38609 0.39435 0.40509 0.41384 0.43223 0.44859 0.45278 0.46785 0.47966 0.49092 0.50376 0.51585 0.52162 0.52726 0.55142 0.57334 0.60361 0.64414 0.67573 0.70840 0.71764 0.72564 0.73185 0.73441 0.73759 0.75063 0.75676 0.76586 0.77888 0.78446 0.78979 0.80338 0.80749 0.81771 0.82503 0.82766 0.83054 0.83661 0.83754 0.84190 0.84759 0.85231 0.85670 0.86430 0.87510 0.89125 0.89759 0.90156 0.91308 0.91796 0.92047 0.94250 0.94977 0.96680 0.97992 1.01920 1.02205 1.02532 1.08080 1.08569 1.09061 1.09980 1.10739 1.11148 1.11381 1.11498 1.12659 1.12976 1.15019 1.15623 1.16162 1.16980 1.17258 1.19014 1.19206 1.19677 1.20401 1.20894 1.21498 1.21893 1.22981 1.23680 1.24054 1.26813 1.27650 1.29933 1.30995 1.31873 1.33051 1.36626 1.39766 1.41372 1.41801 1.42689 1.44738 1.46291 1.47153 1.49948 1.51272 1.53840 1.57722 1.58986 1.60824 1.61145 1.64130 1.65129 1.68098 1.69517 1.70319 1.71419 1.72543 1.73593 1.75124 1.76002 1.76673 1.77280 1.77516 1.78031 1.78480 1.79319 1.83709 1.85420 1.89619 1.93331 1.99042 2.03291 2.04482 2.09718 2.11731 2.12136 2.13208 2.13739 2.14680 2.16317 2.18451 2.19592 2.20628 2.21867 2.22473 2.24477 2.24650 2.29795 2.30204 2.31009 2.32478 2.33924 2.35194 2.37250 2.40945 2.42433 2.43089 2.43663 2.45213 2.46134 2.46631 2.47858 2.50041 2.50773 2.52974 2.55242 2.58493 2.59244 2.60504 2.60667 2.62227 2.62919 2.64626 2.64716 2.68036 2.69704 2.71688 2.78194 2.80104 2.82129 2.83410 2.85626 2.88994 2.90459 2.92504 2.93814 2.95893 2.97088 2.98840 2.99287 3.00795 3.02685 3.05733 3.06605 3.09280 3.10136 3.11414 3.13236 3.14047 3.17061 3.17456 3.19690 3.21655 3.22918 3.27312 3.30295 3.33537 3.48717 3.57771 3.59809 3.62876 3.83037 3.91189 4.47019 4.51326 4.52738 4.52989 4.54382 4.55760 4.55880 4.66484 4.69707 4.74776 4.75680 4.77869 4.83339 4.89956 4.93889 4.94352 5.09889 5.15809 5.26573
11.60937
-1.8743 1.1988 -0.0529 2.2255 |XX|YY|ZZ|XY|XZ|YZ| -100.2901 -105.3861 -113.1523 6.4828 -2.1987 1.8751
|XX|YY|ZZ|XY|XZ|YZ| 5.9861 0.8900 -6.8761 6.4828 -2.1987 1.8751
|XXX|YYY|ZZZ|XYY|XXY|XXZ|XZZ|YZZ|YYZ|XYZ| 10.7509 11.3545 -5.8151 -8.1449 5.4292 22.2799 -3.3530 0.5799 -1.9737 -22.2770
|XXXX|YYYY|ZZZZ|XXXY|XXXZ|YYYX|YYYZ|ZZZX|ZZZY|XXYY|XXZZ|YYZZ|XXYZ|YYXZ|ZZXY| -9166.1915 -722.1093 -339.9858 100.1742 -75.9166 51.2326 1.7445 -6.8137 4.1047 -1713.5387 -1873.3949 -178.3804 41.6365 -17.2241 -12.9693
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25.1633 139.3229 310.8780 48.5086 232.9548 50.2203 68.0772 0.7385 0.7498 0.7483 0.6558 0.7363 0.7093 0.7186 0.3653 0.7500 0.5298 0.4203 0.6534 0.3683 0.7458 0.7029 0.7055 0.4062 0.7469 0.5598 0.7498 0.7388 0.6394 0.7465 0.7487 0.7382 0.6745 0.1908 0.4634 0.1708 0.7238 0.6247 0.5335 0.1131 0.7495 0.7499 0.7500 0.7215 0.7496 0.7232 0.7490 0.2204 0.0410 0.7098 0.7496 0.1878 0.2024 0.6167 0.2644 0.6511 0.7452 0.3780 0.7184 0.6126 0.7175 0.3687 0.4060 0.7498 0.5178 0.2112 0.3209 0.6444 0.1311 0.7422 0.3540 0.2510 0.4517 0.2223 0.4095 0.2423 0.7351 0.4820 0.3954 0.3179 0.3004 0.2554 0.4183 0.5344 0.5203 0.3681 0.3054 0.1375 0.1478 0.3727 0.7467 0.7074 0.4990 0.7471 0.5062 0.1120 0.3365 0.1331 0.7100 0.1640 0.8496 0.8570 0.8560 0.7921 0.8481 0.8300 0.8362 0.5351 0.8571 0.6926 0.5918 0.7904 0.5383 0.8544 0.8255 0.8273 0.5777 0.8551 0.7178 0.8570 0.8498 0.7801 0.8549 0.8563 0.8494 0.8056 0.3205 0.6334 0.2918 0.8397 0.7690 0.6958 0.2032 0.8568 0.8571 0.8571 0.8383 0.8569 0.8394 0.8565 0.3612 0.0787 0.8303 0.8569 0.3162 0.3367 0.7629 0.4182 0.7887 0.8540 0.5487 0.8361 0.7597 0.8355 0.5388 0.5775 0.8570 0.6823 0.3487 0.4859 0.7838 0.2318 0.8520 0.5229 0.4013 0.6223 0.3637 0.5811 0.3901 0.8473 0.6505 0.5667 0.4824 0.4620 0.4069 0.5899 0.6966 0.6845 0.5381 0.4679 0.2417 0.2575 0.5431 0.8550 0.8287 0.6658 0.8552 0.6721 0.2015 0.5035 0.2350 0.8304 0.2818
298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 6 6 6 6 6 6 6 1 6 6 1 7 6 7 6 6 6 6 6 6 8 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 1.00783 12.00000 12.00000 1.00783 14.00307 12.00000 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 15.99491 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
1100.2019 13651.7804 14210.5988 1.00000 0.00188 -0.00055 -0.00188 0.99992 0.01236 0.00057 -0.01236 0.99992 1 0.07873 0.00634 0.00610 1.64037 0.13220 0.12700 35.27 49.41 57.11 105.54 143.24 233.24 271.35 314.93 401.55 424.54 504.79 551.74 616.39 655.31 695.28 701.07 787.23 827.84 847.96 899.73 919.90 973.37 978.66 995.87 1119.04 1138.81 1192.65 1194.75 1197.64 1218.93 1232.47 1337.68 1355.35 1370.86 1400.48 1407.23 1448.33 1490.78 1511.98 1518.92 1564.45 1567.62 1579.45 1583.06 1588.63 1604.66 1616.56 1637.95 1691.75 1713.06 1740.59 1744.99 1774.51 1777.73 1791.32 1852.45 1873.85 1884.51 1900.51 1920.79 1945.74 1956.41 2051.52 2068.24 2111.32 2158.37 2235.02 2259.08 2304.26 2327.82 2355.35 2362.63 2385.24 2416.79 2560.80 2566.38 2608.51 2614.78 2667.40 4766.98 4788.49 4806.60 4822.45 4828.81 4838.29 4844.99 4857.25 4863.48 4875.13 4886.90 4893.08 4911.69 5536.83 0.286616 0.300351 0.301295 0.243200 -797.500891 -797.487156 -797.486212 -797.544307 1.948516D-04
MUNgauss RevisionA2.1 retrievium 30-Apr-2021 DUDE c1ccc(cc1)[C@H]2C[C@@H]2Nc3nc4ccccc4o3 C44416909 RHF 6-31G(d) (6D,10F) C1 250.110613 |X|Y|Z| 15.690183 23.666098 85.224381
31.630508 19 6 7 8 16 2 1
|36.858105| |13.767163|36.858105| |7.934190|13.747167|36.858105| |6.803485|7.880665|13.700936|36.858105| |7.924826|6.893700|7.978573|13.676071|36.858105| |13.744584|7.971263|6.905124|7.888048|13.766040|36.858105| |4.434735|5.046231|7.652392|12.732965|7.511724|5.009318|36.858105| |3.960318|4.763444|7.285372|8.799471|5.536689|4.159607|17.705812|0.500000| |3.602576|3.807714|4.986190|7.226848|6.056674|4.228264|12.683082|0.242889|36.858105| |3.619452|3.837305|5.036947|7.264026|6.037530|4.232065|12.673607|0.243293|12.795303|36.858105| |3.761704|3.795069|4.713225|6.810753|6.620749|4.606703|8.626709|0.172933|8.653031|17.672684|0.500000| |2.958301|3.195580|4.055562|5.035681|4.227577|3.279704|7.620107|0.203204|7.578041|13.309967|0.248128|53.358707| |2.489856|2.622126|3.165539|3.799248|3.421517|2.763599|5.125450|0.137007|5.789893|7.796172|0.183985|19.158345|36.858105| |2.188676|2.307693|2.717950|3.114857|2.835006|2.379101|3.938783|0.109560|4.195823|5.252272|0.132742|11.042373|14.916553|53.358707| |1.964415|2.036458|2.347408|2.683699|2.521317|2.147771|3.284271|0.089679|3.670986|4.237564|0.111351|7.560530|9.074395|18.634403|36.858105| |1.724072|1.780093|2.012896|2.249007|2.136315|1.864392|2.655821|0.073208|2.904894|3.243858|0.086930|5.437478|5.498298|10.234316|13.770590|36.858105| |1.604014|1.638813|1.831746|2.046322|1.977364|1.741180|2.375302|0.064781|2.647368|2.848393|0.077362|4.504671|4.324888|6.964666|8.040747|13.722410|36.858105| |1.653894|1.675138|1.871538|2.119172|2.074181|1.816371|2.461286|0.066025|2.838115|2.969257|0.081135|4.520799|4.312127|6.284632|6.902395|7.841693|13.680637|36.858105| |1.861277|1.882015|2.129003|2.467447|2.418190|2.073742|2.929978|0.077193|3.529133|3.661616|0.099571|5.511837|5.467848|7.252117|7.814500|6.704451|7.861859|13.703091|36.858105| |2.051994|2.100871|2.424386|2.843083|2.721416|2.286398|3.506792|0.092664|4.215341|4.642469|0.122925|7.594213|8.912858|11.500028|13.766276|7.970365|7.042763|8.146915|13.892505|36.858105| |2.397444|2.466447|2.922445|3.565748|3.361008|2.714828|4.663214|0.119159|6.001492|6.880151|0.173362|11.298437|14.231999|11.649226|8.615585|5.413197|4.698458|5.203246|7.709538|13.907378|73.516695| |17.718518|8.904832|5.640543|4.915899|5.638517|8.900031|3.546998|0.090231|3.004831|3.017304|0.087408|3.463056|2.192033|2.665189|1.776680|1.578856|1.478165|1.521624|1.695475|1.848566|3.772708|0.500000| |8.915006|17.712306|8.929458|5.626267|4.962392|5.656100|4.121123|0.113687|3.220635|3.246428|0.088351|3.843499|2.357567|2.879065|1.873833|1.657193|1.527286|1.551125|1.723293|1.912907|3.926125|0.214414|0.500000| |5.650972|8.938577|17.702947|8.915604|5.659502|4.967570|7.122146|0.225622|4.678598|4.734631|0.117602|5.561449|3.172197|3.760191|2.359929|2.029499|1.833022|1.854983|2.094798|2.399181|5.098139|0.124215|0.216351|0.500000| |5.654342|4.962515|5.652147|8.872293|17.711077|8.973286|6.890923|0.138885|6.627738|6.529441|0.217290|5.993134|3.673258|4.067827|2.702505|2.270706|2.118760|2.256194|2.674650|2.994754|6.672485|0.124387|0.107679|0.124021|0.500000| |8.911603|5.657973|4.968247|5.629001|8.940452|17.711698|4.083757|0.095716|3.695542|3.690878|0.114241|3.985256|2.547053|3.014891|2.034824|1.783042|1.682883|1.765538|2.007720|2.179575|4.530832|0.214504|0.124187|0.107764|0.217506|0.500000| |3.078405|3.301155|4.218041|5.435203|4.577820|3.466847|8.608537|0.216741|17.735610|8.657898|0.171967|9.640194|5.879524|5.887422|3.846071|3.038956|2.775167|2.984501|3.725538|4.448035|11.076009|0.073070|0.080172|0.116044|0.134851|0.085783|0.500000| |3.705254|3.723611|4.610642|6.686353|6.584971|4.561084|8.560403|0.171979|17.721118|8.636139|0.213054|7.607545|4.728967|4.888155|3.290566|2.670054|2.498817|2.732216|3.401512|3.868776|9.336355|0.086268|0.086778|0.115115|0.222536|0.113753|0.292375|0.500000| |2.947648|3.243925|4.105303|4.814357|3.971916|3.178702|6.701885|0.193754|5.791118|9.153990|0.200816|26.009304|9.702786|10.359933|5.007187|3.783973|3.086119|3.001993|3.499893|4.649732|10.758189|0.070737|0.080697|0.117914|0.110602|0.078383|0.150851|0.125640|0.500000| |1.652837|1.715686|1.930673|2.122744|2.004543|1.767472|2.477557|0.069223|2.630402|2.957338|0.079248|4.974235|4.739366|9.045641|8.886803|17.738093|8.841762|5.591492|4.865458|5.650721|7.777464|0.042220|0.044707|0.054478|0.058433|0.046871|0.076009|0.066940|0.100131|0.500000| |1.474014|1.504357|1.665643|1.838035|1.781498|1.588536|2.099844|0.057579|2.304563|2.460482|0.067130|3.830226|3.511396|5.590546|5.692216|8.939787|17.716779|8.933263|5.625498|5.039690|6.603359|0.037985|0.039199|0.046392|0.052662|0.042808|0.066860|0.060847|0.074258|0.213746|0.500000| |1.544068|1.555031|1.719616|1.933642|1.910616|1.692500|2.207322|0.059156|2.535097|2.601366|0.071598|3.849754|3.501509|4.987119|4.968130|5.614138|8.911606|17.725267|8.927796|5.736086|7.399219|0.039714|0.040140|0.047227|0.057689|0.046032|0.073815|0.068955|0.071662|0.123527|0.216535|0.500000| |1.885648|1.888515|2.124969|2.480988|2.471613|2.120220|2.912406|0.075612|3.605320|3.581742|0.098364|5.090248|4.720895|5.901335|5.586539|4.865779|5.591752|8.808057|17.740699|8.885713|12.085804|0.047759|0.047856|0.057549|0.076959|0.057456|0.105379|0.099993|0.089095|0.106066|0.123491|0.212521|0.500000|
796.953482 -4384.839085 1638.382137 -109.756686 -2059.260152 1261.472630 -797.787522 2.001047 40A1CFFFFFFFFFFC 42C16B71624B8801 4250E44EEAF3E8BB 4185EE2000000002 B7A16C2614EA07FF 4301351F95830770