Version2.0 2020-07-31T00:13:37Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 21-Jul-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE c1ccc2c(c1)CC[C@@H](C2=O)[C@]3(c4ccccc4N(C3=O)Cc5cccs5)O C09926033 RHF 6-31G(d) (6D,7F) c1ccc2c(c1)CC[C@@H](C2=O)[C@]3(c4ccccc4N(C3=O)Cc5cccs5)O C01[X(C23H19N1O3S1)] 135 C1 462 O=C1c2ccccc2CC[C@@H]1[C@]1(O)C(=O)N(c2c1cccc2)Cc1cccs1 O=C1c2ccccc2CC[C@@H]1[C@]1(O)C(=O)N(c2c1cccc2)Cc1cccs1 O[C@@]1([C@H]2CCc3ccccc3C2=O)C(=O)N(Cc4sccc4)c5ccccc15 InChIKey=OGDSGZXUUYNANL-CVDCTZTESA-N InChI=1S/C23H19NO3S/c25-21-17-8-2-1-6-15(17)11-12-19(21)23(27)18-9-3-4-10-20(18)24(22(23)26)14-16-7-5-13-28-16/h1-10,13,19,27H,11-12,14H2/t19-,23-/m0/s1 InChI=1/C23H19NO3S/c25-21-17-8-2-1-6-15(17)11-12-19(21)23(27)18-9-3-4-10-20(18)24(22(23)26)14-16-7-5-13-28-16/h1-10,13,19,27H,11-12,14H2/t19-,23-/m0/s1 c1ccc2c(c1)CC[C@@H](C2=O)[C@]3(c4ccccc4N(C3=O)Cc5cccs5)O C01[X(C23H19N1O3S1)] 135 C01 462 O=C1c2ccccc2CC[C@@H]1[C@]1(O)C(=O)N(c2c1cccc2)Cc1cccs1 O=C1N(CC2=[CH][CH]=CS2)[C]2[C]([CH][CH][CH][CH]2)[C@]1(O)[C@H]1CC[C]2[C]([CH][CH][CH][CH]2)C1=O O[C@@]1([C]2[CH][CH][CH][CH][C]2N(Cc3sccc3)C1=O)[C@H]4CC[C]5[CH][CH][CH][CH][C]5C4=O InChIKey=OGDSGZXUUYNANL-CVDCTZTESA-N InChI=1S/C23H19NO3S/c25-21-17-8-2-1-6-15(17)11-12-19(21)23(27)18-9-3-4-10-20(18)24(22(23)26)14-16-7-5-13-28-16/h1-10,13,19,27H,11-12,14H2/t19-,23-/m0/s1 InChI=1/C23H19NO3S/c25-21-17-8-2-1-6-15(17)11-12-19(21)23(27)18-9-3-4-10-20(18)24(22(23)26)14-16-7-5-13-28-16/h1-10,13,19,27H,11-12,14H2/t19-,23-/m0/s1 2739.3164132157 -1558.605756 1-A 11176.7379 102 360 462 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -91.96014 -20.57895 -20.55797 -20.53854 -15.60563 -11.35149 -11.33636 -11.31277 -11.28481 -11.28180 -11.25827 -11.25635 -11.25153 -11.24970 -11.24711 -11.24639 -11.24268 -11.24244 -11.23946 -11.23601 -11.23594 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10.69807
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|XX|YY|ZZ|XY|XZ|YZ| 12.3662 2.7427 -15.1089 5.0491 -1.4692 3.7124
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4095.0059 6.5750 5.1609 6.3420 6.4143 5.1400 5.3980 6.6755 6.6685 4.5504 4.4410 4.6764 5.1173 3.7655 5.5231 7.6593 3.3605 2.8763 3.0419 2.4149 2.7308 2.6280 6.0103 3.8400 4.5617 5.0693 4.3181 3.2845 4.4940 8.0939 3.7954 4.2204 4.0850 4.9682 3.6819 4.4388 4.4679 5.5986 5.4444 3.5832 5.9346 4.9917 4.9949 3.9887 7.4694 1.2026 5.0796 1.9492 3.2309 1.4310 1.9409 5.5604 3.6108 4.3151 2.5320 1.8890 1.4644 1.5665 1.4642 3.3036 2.3900 1.4432 1.4097 2.7144 1.4355 1.3628 2.5368 2.4516 2.4689 1.3952 1.9549 2.9728 2.2342 2.2801 2.5156 2.1805 1.7638 2.8460 2.3380 1.9556 2.0628 2.1733 1.4346 1.7287 2.1045 1.7623 1.7743 2.5203 1.7053 1.5348 1.4295 1.5150 1.4136 1.3255 1.6923 1.9153 1.7591 1.5553 2.1720 3.3668 1.8075 1.4770 2.2582 1.1428 1.5217 1.6369 4.9367 1.2129 1.9353 3.0988 6.1786 5.3475 6.3344 5.4953 6.5274 12.9020 12.3462 1.0755 1.0782 1.0708 1.0899 1.0698 1.0948 1.1017 1.0882 1.0878 1.0918 1.0922 1.0960 1.0961 1.0910 1.0958 1.0947 1.0958 1.0997 1.0671 0.0022 0.0021 0.0058 0.0097 0.0117 0.0164 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MUNgauss RevisionA2.0 retrievium 31-Jul-2020 DUDE c1ccc2c(c1)CC[C@@H](C2=O)[C@]3(c4ccccc4N(C3=O)Cc5cccs5)O C09926033 RHF 6-31G(d) (6D,10F) C1 389.108565 |X|Y|Z| 53.305883 36.045274 83.880581
54.420388 25 6 7 16 23 1 1
|36.858105| |13.700072|36.858105| |7.974924|13.832280|36.858105| |6.888426|7.915873|13.653165|36.858105| |7.900029|6.806387|7.871411|13.670743|36.858105| |13.797485|7.919853|6.890299|7.956084|13.682882|36.858105| |5.015493|4.417491|4.995875|7.529427|12.586150|7.547468|36.858105| |3.873106|3.731912|4.484863|6.641360|7.522638|5.006055|12.470936|36.858105| |3.705106|3.840569|4.975662|7.440443|6.553498|4.435134|7.607851|12.382900|36.858105| |3.636970|3.715767|4.661219|6.626450|6.185953|4.354424|7.226546|8.938427|17.477642|0.500000| |4.475334|5.072119|7.678305|12.771225|7.580308|5.045387|6.473625|7.655948|12.548308|0.251719|36.858105| |3.833591|4.567836|6.813206|8.106290|5.302620|4.020078|4.613526|5.409694|8.001532|0.178659|15.902478|73.516695| |2.885617|3.032320|3.784497|4.869609|4.317015|3.281796|4.881041|7.354871|12.378492|0.249929|7.462150|12.111194|36.858105| 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|2.165466|2.413650|2.877625|2.997549|2.555926|2.214368|2.490211|2.942008|3.421029|0.083282|3.697061|8.082810|4.056245|4.279443|3.430278|3.343925|3.963937|5.485221|5.873179|10.475057|5.466655|8.863439|12.620659|36.858105| |2.415104|2.774706|3.380565|3.399973|2.791951|2.421640|2.620436|3.023388|3.579918|0.087251|4.174143|9.762508|3.985515|4.216006|3.450037|3.348166|3.868542|5.051659|5.412273|8.692586|5.053070|8.181601|7.390700|14.165646|36.858105| |2.218577|2.559295|3.004820|2.897395|2.426309|2.174439|2.250764|2.504798|2.868477|0.071987|3.330897|7.388606|3.074909|3.252808|2.824379|2.824604|3.247146|3.950692|3.944427|5.903923|3.663175|6.172507|5.022908|8.213552|13.237566|36.858105| |1.932277|2.177905|2.494007|2.443601|2.109538|1.908643|1.998026|2.226439|2.496368|0.063192|2.777925|5.893374|2.725396|2.879526|2.529276|2.566744|2.987858|3.622629|3.513608|5.286043|3.253534|5.569466|4.816256|7.670461|8.213909|14.192702|36.858105| |1.844298|2.035218|2.338889|2.380186|2.088491|1.863999|2.037116|2.332440|2.607909|0.065441|2.776345|5.779539|2.986005|3.148100|2.695698|2.722149|3.228729|4.117141|4.017314|6.373430|3.718989|6.353412|6.773985|10.950092|7.455666|7.472845|11.017975|388.023441| |2.573211|2.610527|3.097870|3.894530|3.770919|2.971290|4.607590|6.868916|8.113459|0.200285|5.116755|8.129585|13.522040|7.907586|5.997766|4.312667|3.853346|4.228969|5.787631|7.923939|7.899672|11.317705|4.200687|3.330463|3.169136|2.558342|2.344157|18.534497|73.516695| |17.710668|8.900669|5.663045|4.959499|5.633173|8.947194|4.094616|3.243391|3.078853|0.084724|3.572583|5.621510|2.486495|2.267861|2.177362|1.950779|1.834309|1.883799|2.085346|2.890734|2.355087|4.239017|1.927606|1.944952|2.151891|2.010604|1.772247|12.000209|4.021600|0.500000| |8.885266|17.724333|8.931954|5.631550|4.917868|5.637970|3.536170|3.099557|3.220466|0.087089|4.129465|7.015017|2.658682|2.515264|2.399485|2.187715|2.093703|2.164349|2.369106|3.260707|2.575430|4.534322|2.185345|2.291725|2.652743|2.518286|2.146055|14.007180|4.104127|0.214351|0.500000| |5.652046|8.913852|17.750680|8.947113|5.633942|4.963888|4.089599|3.942731|4.604636|0.119221|7.198985|13.683989|3.739276|3.586291|3.292463|2.936915|2.829502|2.999421|3.382997|4.629164|3.637299|6.138307|2.983621|3.176771|3.889910|3.480490|2.801758|18.205378|5.331904|0.124123|0.214056|0.500000| |8.941268|5.639482|4.960061|5.652014|8.914068|17.704408|7.018088|4.582843|3.878145|0.107303|4.100410|5.956906|2.969025|2.566960|2.439600|2.109111|1.945632|2.004471|2.281382|3.185507|2.712151|4.939417|2.071850|2.009109|2.160539|1.953532|1.740559|12.194402|4.959617|0.216224|0.124090|0.107693|0.500000| |4.731373|3.983984|4.230826|5.702684|8.922816|7.116189|17.556943|8.839378|5.521282|0.144381|4.904634|6.725756|4.031063|3.170931|2.895811|2.400491|2.198780|2.307775|2.736053|3.915613|3.568048|6.671998|2.471639|2.284462|2.379992|2.075383|1.864999|13.547656|7.075115|0.112156|0.090685|0.097683|0.212103|0.500000| |4.530626|3.989485|4.402349|6.148685|8.940937|6.470439|17.488792|8.859490|6.786253|0.211797|5.529846|7.311614|4.572463|3.687116|3.517911|2.823422|2.485476|2.536103|3.005845|4.081807|3.649235|6.331485|2.495269|2.299963|2.407345|2.086396|1.864688|13.531080|7.993857|0.106004|0.090782|0.102565|0.176775|0.304070|0.500000| |3.774543|3.680530|4.400903|6.196011|6.660286|4.723886|8.819491|17.583314|8.818536|0.174559|7.020228|9.503542|6.557102|4.380404|3.579669|2.878142|2.705967|3.000468|3.817954|5.936919|6.276264|12.896595|3.572905|3.144445|3.215705|2.648757|2.355969|17.630785|10.597401|0.088445|0.085721|0.108906|0.119973|0.215687|0.173693|0.500000| |3.257063|3.107260|3.594127|4.871840|5.510500|4.104282|8.851987|17.642757|8.835399|0.211260|5.557918|7.713479|6.914572|4.599197|3.953113|3.072260|2.771046|2.961329|3.723944|5.369079|5.364091|9.641590|3.170759|2.732727|2.732387|2.285420|2.071211|15.691663|14.330110|0.078318|0.073663|0.090078|0.109866|0.210000|0.218142|0.303590|0.500000| |2.561506|2.689361|3.206160|3.774946|3.439673|2.818358|3.686968|4.238606|5.904592|0.206534|4.789470|8.125307|6.532469|8.926026|17.706516|8.873692|5.638177|4.907884|5.638638|5.865614|4.437375|6.339733|3.282460|2.930471|2.975976|2.495045|2.242953|16.790394|10.537922|0.062778|0.067276|0.089233|0.071993|0.085860|0.109948|0.100105|0.117028|0.500000| |2.063125|2.212911|2.566474|2.777387|2.495288|2.164578|2.538436|2.805354|3.547466|0.108549|3.329455|6.226824|4.009388|5.667377|8.886173|17.727311|8.925488|5.616730|4.974901|4.972602|3.341372|4.920141|3.030698|2.836781|2.863328|2.496918|2.290726|17.018782|6.508972|0.051819|0.057598|0.074612|0.055628|0.061978|0.073478|0.071095|0.076812|0.213999|0.500000| |1.863069|2.032328|2.359565|2.480625|2.188768|1.918853|2.187767|2.459746|3.031844|0.085500|2.991589|5.973386|3.582882|4.978791|5.643166|8.945190|17.715557|8.935299|5.696430|5.618036|3.387460|4.999422|3.679481|3.566976|3.485573|3.066814|2.885992|21.898860|5.655775|0.047057|0.053799|0.070668|0.049162|0.054470|0.060963|0.065308|0.066594|0.124073|0.215826|0.500000| |1.958471|2.153757|2.547060|2.697615|2.339216|2.022695|2.336042|2.731740|3.355527|0.087932|3.373453|7.092771|4.225627|5.610718|4.911080|5.614488|8.863306|17.747936|8.878877|9.199634|4.618378|6.647315|6.598084|6.331940|5.468216|4.387156|4.191332|35.368968|6.351036|0.049094|0.056720|0.077154|0.051472|0.058488|0.062812|0.075506|0.072986|0.106798|0.123778|0.215028|0.500000| |2.149373|2.309020|2.720510|2.994477|2.667565|2.275667|2.738892|3.416095|3.772594|0.088786|3.719035|7.412994|4.767308|4.441406|3.402634|3.125898|3.483478|4.631581|5.680777|12.747080|7.589212|13.957086|17.625582|8.913859|6.055061|4.435656|4.333420|42.320788|7.347562|0.053594|0.059601|0.079196|0.058289|0.070797|0.069345|0.105183|0.090738|0.082584|0.073846|0.085206|0.133845|0.500000| |1.937100|2.088569|2.446597|2.654551|2.361693|2.034015|2.421654|2.945777|3.389631|0.083760|3.297425|6.664624|4.422841|4.750230|3.744855|3.651462|4.395038|6.367566|6.881744|12.549575|5.950179|9.215932|17.547051|8.908463|5.677327|4.322478|4.407742|46.585164|6.943942|0.048625|0.054470|0.072102|0.052280|0.062022|0.063254|0.085820|0.079751|0.087555|0.084813|0.107990|0.204461|0.302845|0.500000| |2.766954|3.242612|4.133945|4.177685|3.278495|2.779061|3.013864|3.494683|4.305340|0.102976|5.377917|13.994490|4.650548|4.866480|3.892787|3.646225|4.057075|5.181641|5.966477|9.328680|5.771794|9.031311|6.569500|8.933283|17.763574|8.573603|5.724947|37.695834|6.245301|0.067254|0.084726|0.135767|0.067667|0.074557|0.076242|0.102650|0.085407|0.093247|0.085748|0.098627|0.143185|0.153934|0.139430|0.500000| |2.304418|2.706556|3.149592|2.927364|2.434096|2.213553|2.211595|2.403980|2.739147|0.069564|3.257533|7.186109|2.835958|2.987820|2.659152|2.661670|2.989319|3.477765|3.469063|5.018685|3.252339|5.513671|4.011888|5.725024|8.583452|17.743298|8.930217|37.748603|4.212044|0.058211|0.075399|0.103686|0.054946|0.056677|0.057064|0.070150|0.060517|0.066251|0.066392|0.079148|0.103912|0.101039|0.097716|0.201462|0.500000| |1.786852|2.003850|2.250520|2.183663|1.909966|1.753083|1.807789|1.985514|2.195274|0.056228|2.426106|5.032795|2.363975|2.489172|2.235041|2.286213|2.632572|3.081202|2.955130|4.347026|2.752198|4.760692|3.834554|5.399737|5.673355|8.765830|17.789446|55.284570|3.683086|0.045978|0.055439|0.069756|0.044684|0.047227|0.047114|0.058127|0.051612|0.055743|0.057620|0.071959|0.097976|0.098627|0.100851|0.122368|0.203651|0.500000| |2.295693|2.344921|2.750707|3.328470|3.190472|2.595621|3.749037|5.128808|5.984867|0.155015|4.272957|7.175527|9.800632|7.798290|6.074145|4.550904|4.140867|4.566381|6.125174|8.108879|7.131504|10.109772|4.371234|3.370303|3.115281|2.525875|2.352379|18.990804|35.711885|0.056733|0.058490|0.075260|0.068077|0.092440|0.102838|0.130323|0.162039|0.159067|0.106380|0.094667|0.106799|0.117596|0.117851|0.093537|0.064373|0.057815|0.500000|
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